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The map label for this gene is 99079947

Identifier: 99079947

GI number: 99079947

Start: 112632

End: 113774

Strand: Reverse

Name: 99079947

Synonym: TM1040_0106

Alternate gene names: NA

Gene position: 113774-112632 (Counterclockwise)

Preceding gene: 99079948

Following gene: 99079938

Centisome position: 3.55

GC content: 62.2

Gene sequence:

>1143_bases
ATGACTATTCACTGGTGCGGCACCGGCCTCTCCGCCATTCCCGGCCTGCGTCGCCTGCTCGAAGCGGGTCACGACGTCGC
CGTCTGGAACCGCACACCCGAAAAAGCCGCCGAGGCTGTTGGGGATCTGACCACCAACATCCACAAATTCTCCATTGCAC
GCCTCTCGGAGCTTCTGAGCCCGGCGGACGTCGTGGTCTCCATGCTGCCCGGCGACTGGCATGTGGAACTCGCCGAGCTC
GCAATTTCCAAGGGGGCGCATTTTGTGTCCTCCTCCTACATCTCGCCGGAGATGCGCGCCCTCGACCAAAAGGCCAAAGA
CGCCGGAGTCGCGCTGGTCAATGAGGTCGGGCTTGATCCGGGCATCGATCACCTGATGGCCCATGCCCTCGTGGCTGAAT
ACGCGGAATCTCCGGCCTTCGACGCGGACAATGAGATCAGCTTTCTGTCCTATTGCGGCGGCATCCCAAAGATCCCGAAC
CCATTTCGCTACAAGTTCAGCTGGTCGCCCCTCGGCGTGCTGAAGGCCCTGCGCTCGCCCTCGCGCTCGATCCGCGATTT
TGAGGTTCTGGACGTGGCGCGCCCCTGGGATGCGATCTCGAGCTATGACGCGCCGCTTGCGACGCCCGAAACCTTTGAGG
TTTATCCCAACCGCGACAGTCTGCCGTTCATGGAGCAGTATCACTTCGACAAGGACTGGAAGGTCAAAACCTTCGTGCGC
GGCACCCTACGTCTGAATGGCTGGACCGAGGCCTGGGCGGATGTCTTCAAAGAAGTCGAAACGCTTGAAGGCCCCGAAGG
CGATGCTCGCCTCAAGGAAATGTCCGATCAGTTCTGGGACGAAAACGCCTATGACGAAGGCGAGCCGGATCGCGTGGTGC
TCTGTGTGGACCTCAAGGCGGAAAAAGACGGCCAGACCAAGTGGCACAAGACCTATGTGATGGACGCATGGGGCGACGAG
CGCGGAAGCGCCATGGCGCGTCTGGTGTCCTATCCGGTGTCCTACGCCATTGAGGCCGCGATGAACGGCAAGATCGCACC
CGGCGTCAGCGCCGCGCCCAGCGATCCGGCGCTGGTGGACAGCTGGATGGGGCGCATCGGCGCACTGGCGCAGCACCTTC
AGGTGGTGTCCCACCGCTCCTGA

Upstream 100 bases:

>100_bases
CCCTGTCCGATCTGGATGCGGGCGTCTGGGGCCGGGCCAAGGCGGTCTTTGACGAACATGTGGCGGGCTGAAAAGCCTGC
CCAGATCAAGGAGAACAACT

Downstream 100 bases:

>100_bases
AGCCGCGCCCCTACTGCGCAAACACTATCAATAGCCTCGCCAGCACCCGCTGGCGGGGCTTTTTGTATGCAACCGCAATT
CGTTAGCGGCCCATCACATC

Product: saccharopine dehydrogenase (NADP+, L-glutamate forming)

Products: NA

Alternate protein names: Saccharopine Reductase; Oxidoreductase; Saccharopine Dehydrogenase-Like Protein; Lysine Oxoglutarate Reductase/Saccharopine Dehydrogenase

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTIHWCGTGLSAIPGLRRLLEAGHDVAVWNRTPEKAAEAVGDLTTNIHKFSIARLSELLSPADVVVSMLPGDWHVELAEL
AISKGAHFVSSSYISPEMRALDQKAKDAGVALVNEVGLDPGIDHLMAHALVAEYAESPAFDADNEISFLSYCGGIPKIPN
PFRYKFSWSPLGVLKALRSPSRSIRDFEVLDVARPWDAISSYDAPLATPETFEVYPNRDSLPFMEQYHFDKDWKVKTFVR
GTLRLNGWTEAWADVFKEVETLEGPEGDARLKEMSDQFWDENAYDEGEPDRVVLCVDLKAEKDGQTKWHKTYVMDAWGDE
RGSAMARLVSYPVSYAIEAAMNGKIAPGVSAAPSDPALVDSWMGRIGALAQHLQVVSHRS

Sequences:

>Translated_380_residues
MTIHWCGTGLSAIPGLRRLLEAGHDVAVWNRTPEKAAEAVGDLTTNIHKFSIARLSELLSPADVVVSMLPGDWHVELAEL
AISKGAHFVSSSYISPEMRALDQKAKDAGVALVNEVGLDPGIDHLMAHALVAEYAESPAFDADNEISFLSYCGGIPKIPN
PFRYKFSWSPLGVLKALRSPSRSIRDFEVLDVARPWDAISSYDAPLATPETFEVYPNRDSLPFMEQYHFDKDWKVKTFVR
GTLRLNGWTEAWADVFKEVETLEGPEGDARLKEMSDQFWDENAYDEGEPDRVVLCVDLKAEKDGQTKWHKTYVMDAWGDE
RGSAMARLVSYPVSYAIEAAMNGKIAPGVSAAPSDPALVDSWMGRIGALAQHLQVVSHRS
>Mature_379_residues
TIHWCGTGLSAIPGLRRLLEAGHDVAVWNRTPEKAAEAVGDLTTNIHKFSIARLSELLSPADVVVSMLPGDWHVELAELA
ISKGAHFVSSSYISPEMRALDQKAKDAGVALVNEVGLDPGIDHLMAHALVAEYAESPAFDADNEISFLSYCGGIPKIPNP
FRYKFSWSPLGVLKALRSPSRSIRDFEVLDVARPWDAISSYDAPLATPETFEVYPNRDSLPFMEQYHFDKDWKVKTFVRG
TLRLNGWTEAWADVFKEVETLEGPEGDARLKEMSDQFWDENAYDEGEPDRVVLCVDLKAEKDGQTKWHKTYVMDAWGDER
GSAMARLVSYPVSYAIEAAMNGKIAPGVSAAPSDPALVDSWMGRIGALAQHLQVVSHRS

Specific function: Unknown

COG id: COG1748

COG function: function code E; Saccharopine dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI13027640, Length=384, Percent_Identity=28.3854166666667, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17541738, Length=356, Percent_Identity=30.8988764044944, Blast_Score=147, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6324378, Length=261, Percent_Identity=35.632183908046, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI23397395, Length=205, Percent_Identity=39.0243902439024, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42034; Mature: 41903

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIHWCGTGLSAIPGLRRLLEAGHDVAVWNRTPEKAAEAVGDLTTNIHKFSIARLSELLS
CEEEEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PADVVVSMLPGDWHVELAELAISKGAHFVSSSYISPEMRALDQKAKDAGVALVNEVGLDP
HHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GIDHLMAHALVAEYAESPAFDADNEISFLSYCGGIPKIPNPFRYKFSWSPLGVLKALRSP
CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHCC
SRSIRDFEVLDVARPWDAISSYDAPLATPETFEVYPNRDSLPFMEQYHFDKDWKVKTFVR
CHHCCCCHHHCCCCCHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHCCCCCCEEEEEEE
GTLRLNGWTEAWADVFKEVETLEGPEGDARLKEMSDQFWDENAYDEGEPDRVVLCVDLKA
EEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECC
EKDGQTKWHKTYVMDAWGDERGSAMARLVSYPVSYAIEAAMNGKIAPGVSAAPSDPALVD
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
SWMGRIGALAQHLQVVSHRS
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIHWCGTGLSAIPGLRRLLEAGHDVAVWNRTPEKAAEAVGDLTTNIHKFSIARLSELLS
EEEEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PADVVVSMLPGDWHVELAELAISKGAHFVSSSYISPEMRALDQKAKDAGVALVNEVGLDP
HHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GIDHLMAHALVAEYAESPAFDADNEISFLSYCGGIPKIPNPFRYKFSWSPLGVLKALRSP
CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHCC
SRSIRDFEVLDVARPWDAISSYDAPLATPETFEVYPNRDSLPFMEQYHFDKDWKVKTFVR
CHHCCCCHHHCCCCCHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHCCCCCCEEEEEEE
GTLRLNGWTEAWADVFKEVETLEGPEGDARLKEMSDQFWDENAYDEGEPDRVVLCVDLKA
EEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECC
EKDGQTKWHKTYVMDAWGDERGSAMARLVSYPVSYAIEAAMNGKIAPGVSAAPSDPALVD
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
SWMGRIGALAQHLQVVSHRS
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA