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The map label for this gene is pntAB [H]

Identifier: 104779422

GI number: 104779422

Start: 109283

End: 109588

Strand: Reverse

Name: pntAB [H]

Synonym: PSEEN0115

Alternate gene names: 104779422

Gene position: 109588-109283 (Counterclockwise)

Preceding gene: 104779423

Following gene: 104779421

Centisome position: 1.86

GC content: 62.42

Gene sequence:

>306_bases
ATGCTGATTTCCCACGGCATCTACAACCTGATCATCTTCGTGCTGGCCATCTACGTGGGCTACCACGTGGTGTGGAACGT
CACCCCGGCCCTGCACACGCCGTTGATGGCGGTCACCAACGCCATTTCCGCGATCGTCATCGTCGGCGCCATGCTGGCCG
CCGCGCTGACCGTCACCCCGGCCGGCAAGGTGATGGGCACCCTGGCCGTGGCGCTGGCCGCGGTCAACGTGTTCGGTGGC
TTCCTGGTCACCCGCCGCATGCTGGAAATGTTCAAGAAGAAAACCAAGAACGAGGCGCAGAAGTAA

Upstream 100 bases:

>100_bases
TGGTCATCAACCTCGAAGACGACATCGTCGCCGCGTGCCTGATGTGCCGCGACGGCCAGGTCGTGCGCAAGAACGGCTGA
GGAGCACGACAATGGAAGAC

Downstream 100 bases:

>100_bases
GCATGAGCATGAATCTGGTAACGCTTCTGTACCTGGTCGCCTCGATCTGCTTCATCCAGGCGCTCAAGGGCCTCTCGCAC
CCGACCACCTCACGCCGCGG

Product: pyridine proton-translocating NAD(P) transhydrogenase

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MLISHGIYNLIIFVLAIYVGYHVVWNVTPALHTPLMAVTNAISAIVIVGAMLAAALTVTPAGKVMGTLAVALAAVNVFGG
FLVTRRMLEMFKKKTKNEAQK

Sequences:

>Translated_101_residues
MLISHGIYNLIIFVLAIYVGYHVVWNVTPALHTPLMAVTNAISAIVIVGAMLAAALTVTPAGKVMGTLAVALAAVNVFGG
FLVTRRMLEMFKKKTKNEAQK
>Mature_101_residues
MLISHGIYNLIIFVLAIYVGYHVVWNVTPALHTPLMAVTNAISAIVIVGAMLAAALTVTPAGKVMGTLAVALAAVNVFGG
FLVTRRMLEMFKKKTKNEAQK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=86, Percent_Identity=52.3255813953488, Blast_Score=90, Evalue=4e-19,
Organism=Homo sapiens, GI122939153, Length=86, Percent_Identity=52.3255813953488, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787887, Length=84, Percent_Identity=55.952380952381, Blast_Score=92, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17550456, Length=86, Percent_Identity=52.3255813953488, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 10797; Mature: 10797

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISHGIYNLIIFVLAIYVGYHVVWNVTPALHTPLMAVTNAISAIVIVGAMLAAALTVTP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGKVMGTLAVALAAVNVFGGFLVTRRMLEMFKKKTKNEAQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLISHGIYNLIIFVLAIYVGYHVVWNVTPALHTPLMAVTNAISAIVIVGAMLAAALTVTP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGKVMGTLAVALAAVNVFGGFLVTRRMLEMFKKKTKNEAQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]