Click here to switch to the map view.

The map label for this gene is thrB [H]

Identifier: 104779387

GI number: 104779387

Start: 70201

End: 71151

Strand: Reverse

Name: thrB [H]

Synonym: PSEEN0074

Alternate gene names: 104779387

Gene position: 71151-70201 (Counterclockwise)

Preceding gene: 104779388

Following gene: 104779385

Centisome position: 1.21

GC content: 64.77

Gene sequence:

>951_bases
ATGTCAGTCTTCACCCCTGTGTCCCGGCCTGAGCTGGAAACCTTTCTGGCGCCGTACGAGCTGGGCCGTCTGCTCGACTT
CCAGGGCATTGCCGCCGGTACCGAGAACAGCAATTTCTTCGTCAGCCTGGAGCAAGGGGAGTTCGTCCTCACACTGATCG
AGCGCGGGCCGGCCGAAGACATGCCGTTCTTCATCGAGCTGCTCGATGTACTGCATGAGGCCGACATGCCGGTGCCCTAC
GCCGTGCGCGACCGCGACGGCAACGGCCTGCGCGAGCTGTGCGGCAAACCGGCGCTGTTGCAGCCACGGTTGTCCGGCAA
GCACATAAAGGCACCGAACAACCAGCACTGCGCGCAGGTTGGCGAGCTGCTGGCGCACATCCACCTGGCCACCCGCGAGC
GCATCATCGAGCGCCGTACCGACCGCGGCCTGGACTGGATGCTGGCATCTGGCATTGAGTTGCTGTCCGGCCTGAACAGC
GCGCAAGCCGAGCTGTTGAAGCCGGCACTGGATGAGATCACCGCGCACAAGGCGCAGATCCTGGCCCTGCCCAAGGCCAA
CCTGCACGCCGACCTGTTCCGTGACAACGTGATGTTCGAAGGCACCCACCTGACCGGCGTGATCGATTTCTACAACGCCT
GTTCCGGGCCGATGCTGTATGACGTGGCCATCACCGTGAACGACTGGTGCCTGGACGAACAGGGTGGCATCGACCTGCCA
CGGGCCCAGGCGCTGCTGGGTGCTTACGCGGCGTTGCGGCCATTCACCGCGGCCGAAGCCGAGCTGTGGCCGGTGATGCT
GCGGGTGGCTTGCGTGCGCTTCTGGCTGTCGCGGCTGATCGCGGCGCAGGCGTTTGCCGGGATGGATGTGATGATCCACG
ACCCGAGCGAGTTCGAGGTGCGCTTGGTGCAGCGCCAGCAGGTGGCGTTGAAGCTGCCGTTCGCGCTCTAA

Upstream 100 bases:

>100_bases
CTGATCCCCTCCTGGAAAATCTTCGAGTGGAAGTAGCGGGTACCGTTCACATCAACCAGGCACTTCCCGGCGGAAGTGCC
CGCATGGGCAATTTCTCAAC

Downstream 100 bases:

>100_bases
CGGGCGATTACAAAAACCTGTAGGAGCGGCTTTAGCCGCGATCACCCGCGAAGCGGGTGCCATACACCGTGGCGCCTGCT
TCGCGGCTGAAGCCGCTCCT

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSVFTPVSRPELETFLAPYELGRLLDFQGIAAGTENSNFFVSLEQGEFVLTLIERGPAEDMPFFIELLDVLHEADMPVPY
AVRDRDGNGLRELCGKPALLQPRLSGKHIKAPNNQHCAQVGELLAHIHLATRERIIERRTDRGLDWMLASGIELLSGLNS
AQAELLKPALDEITAHKAQILALPKANLHADLFRDNVMFEGTHLTGVIDFYNACSGPMLYDVAITVNDWCLDEQGGIDLP
RAQALLGAYAALRPFTAAEAELWPVMLRVACVRFWLSRLIAAQAFAGMDVMIHDPSEFEVRLVQRQQVALKLPFAL

Sequences:

>Translated_316_residues
MSVFTPVSRPELETFLAPYELGRLLDFQGIAAGTENSNFFVSLEQGEFVLTLIERGPAEDMPFFIELLDVLHEADMPVPY
AVRDRDGNGLRELCGKPALLQPRLSGKHIKAPNNQHCAQVGELLAHIHLATRERIIERRTDRGLDWMLASGIELLSGLNS
AQAELLKPALDEITAHKAQILALPKANLHADLFRDNVMFEGTHLTGVIDFYNACSGPMLYDVAITVNDWCLDEQGGIDLP
RAQALLGAYAALRPFTAAEAELWPVMLRVACVRFWLSRLIAAQAFAGMDVMIHDPSEFEVRLVQRQQVALKLPFAL
>Mature_315_residues
SVFTPVSRPELETFLAPYELGRLLDFQGIAAGTENSNFFVSLEQGEFVLTLIERGPAEDMPFFIELLDVLHEADMPVPYA
VRDRDGNGLRELCGKPALLQPRLSGKHIKAPNNQHCAQVGELLAHIHLATRERIIERRTDRGLDWMLASGIELLSGLNSA
QAELLKPALDEITAHKAQILALPKANLHADLFRDNVMFEGTHLTGVIDFYNACSGPMLYDVAITVNDWCLDEQGGIDLPR
AQALLGAYAALRPFTAAEAELWPVMLRVACVRFWLSRLIAAQAFAGMDVMIHDPSEFEVRLVQRQQVALKLPFAL

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 35109; Mature: 34978

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFTPVSRPELETFLAPYELGRLLDFQGIAAGTENSNFFVSLEQGEFVLTLIERGPAED
CCCCCCCCCCHHHHHHCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCC
MPFFIELLDVLHEADMPVPYAVRDRDGNGLRELCGKPALLQPRLSGKHIKAPNNQHCAQV
CHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHCCCCCEECCCCCCCEECCCCCHHHHHH
GELLAHIHLATRERIIERRTDRGLDWMLASGIELLSGLNSAQAELLKPALDEITAHKAQI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEE
LALPKANLHADLFRDNVMFEGTHLTGVIDFYNACSGPMLYDVAITVNDWCLDEQGGIDLP
EECCCCCCHHHHHHCCEEEECCHHHHHHHHHHCCCCCEEEEEEEEEECEEECCCCCCCCH
RAQALLGAYAALRPFTAAEAELWPVMLRVACVRFWLSRLIAAQAFAGMDVMIHDPSEFEV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHH
RLVQRQQVALKLPFAL
HHHHHHHHEEECCCCC
>Mature Secondary Structure 
SVFTPVSRPELETFLAPYELGRLLDFQGIAAGTENSNFFVSLEQGEFVLTLIERGPAED
CCCCCCCCCHHHHHHCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCC
MPFFIELLDVLHEADMPVPYAVRDRDGNGLRELCGKPALLQPRLSGKHIKAPNNQHCAQV
CHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHCCCCCEECCCCCCCEECCCCCHHHHHH
GELLAHIHLATRERIIERRTDRGLDWMLASGIELLSGLNSAQAELLKPALDEITAHKAQI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEE
LALPKANLHADLFRDNVMFEGTHLTGVIDFYNACSGPMLYDVAITVNDWCLDEQGGIDLP
EECCCCCCHHHHHHCCEEEECCHHHHHHHHHHCCCCCEEEEEEEEEECEEECCCCCCCCH
RAQALLGAYAALRPFTAAEAELWPVMLRVACVRFWLSRLIAAQAFAGMDVMIHDPSEFEV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHH
RLVQRQQVALKLPFAL
HHHHHHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA