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The map label for this gene is hdtS [H]

Identifier: 104779328

GI number: 104779328

Start: 16126

End: 16896

Strand: Reverse

Name: hdtS [H]

Synonym: PSEEN0014

Alternate gene names: 104779328

Gene position: 16896-16126 (Counterclockwise)

Preceding gene: 162139702

Following gene: 104779325

Centisome position: 0.29

GC content: 63.94

Gene sequence:

>771_bases
ATGTCGATCCTGCAGGCGATCAGAATCTTTCTTTTTTACCTGCTGTTGGGCACCAGTTCGCTGCTGTGGTGCTCGCTGAG
CTTCTTCGTCGCGCCTTTCCTGCCGTTCCCCAAGCGCTACAAGTTCATCAACGTGTACTGGTGCCGCTGCGCGCTGTTCC
TGGTGAAGACGATCCTCGGGATCGACTACAAGATCACCGGCGCCGAACATGTGCCTGATGTGCCGTGCGTGATCCTGTCG
AACCACCAGAGCACCTGGGAGACGTTCTTCCTTTCGGCGTACTTCTCGCCGCTGAGCCAGGTACTCAAGCGCGAGCTGCT
GTACGTGCCGTTCTTCGGCTGGGCCATGGCCATGCTGCGACCGATCGCCATCGACCGGAAGAACCCGAAAGAGGCCTTGC
GCCAGGTTGCCAGCCAGGGTGACGAGTTGCTCAAACAGGGCACCTGGGTGCTGATCTTCCCCGAAGGCACCCGCGTGCCC
CACGGCCAGATGGGCAAGTTCTCCCGCGGTGGCACCGCGCTCGCAGTGAATGCCGGCCTGCCGGTGCTGCCGATCGCCCA
CAACGCCGGCAAGTTCTGGCCCCGTGAAGGCTGGGGCAAGCGCCCGGGCACCATCGAGGTGGTAATTGGCGCGCCGATGT
ACCCGGAAGGGACGGGGCCACGGGCCATTGCCGAGCTCAACGACCGCGCCCAGGCGTGGAACGAGGCAGCCCAGCGGGCC
ATGGGTTCGCTGCCGCCGGTGGCGGAAAATCCGGAACAGCAGCACGCCTGA

Upstream 100 bases:

>100_bases
ACGATCTGGCAGCCATCGCCAGAGAACTTATTTAAATGAGTGCGCCAGGAACGGCGCACTTTTCATTAGGCGGGCACGCC
CCGCAACGGTACATGCCACT

Downstream 100 bases:

>100_bases
CGTTCTGTGGATAAGTTGTTAGCAATTTTGGGATTACGTGTGTCATAACATAGCTAACCTGTTGAATTAGCTATTTATTT
CTCTGTATGACGTTTTTCTG

Product: N-acylhomoserine lactone synthase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSILQAIRIFLFYLLLGTSSLLWCSLSFFVAPFLPFPKRYKFINVYWCRCALFLVKTILGIDYKITGAEHVPDVPCVILS
NHQSTWETFFLSAYFSPLSQVLKRELLYVPFFGWAMAMLRPIAIDRKNPKEALRQVASQGDELLKQGTWVLIFPEGTRVP
HGQMGKFSRGGTALAVNAGLPVLPIAHNAGKFWPREGWGKRPGTIEVVIGAPMYPEGTGPRAIAELNDRAQAWNEAAQRA
MGSLPPVAENPEQQHA

Sequences:

>Translated_256_residues
MSILQAIRIFLFYLLLGTSSLLWCSLSFFVAPFLPFPKRYKFINVYWCRCALFLVKTILGIDYKITGAEHVPDVPCVILS
NHQSTWETFFLSAYFSPLSQVLKRELLYVPFFGWAMAMLRPIAIDRKNPKEALRQVASQGDELLKQGTWVLIFPEGTRVP
HGQMGKFSRGGTALAVNAGLPVLPIAHNAGKFWPREGWGKRPGTIEVVIGAPMYPEGTGPRAIAELNDRAQAWNEAAQRA
MGSLPPVAENPEQQHA
>Mature_255_residues
SILQAIRIFLFYLLLGTSSLLWCSLSFFVAPFLPFPKRYKFINVYWCRCALFLVKTILGIDYKITGAEHVPDVPCVILSN
HQSTWETFFLSAYFSPLSQVLKRELLYVPFFGWAMAMLRPIAIDRKNPKEALRQVASQGDELLKQGTWVLIFPEGTRVPH
GQMGKFSRGGTALAVNAGLPVLPIAHNAGKFWPREGWGKRPGTIEVVIGAPMYPEGTGPRAIAELNDRAQAWNEAAQRAM
GSLPPVAENPEQQHA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=191, Percent_Identity=32.4607329842932, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI15100175, Length=191, Percent_Identity=32.4607329842932, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI6041665, Length=205, Percent_Identity=25.8536585365854, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564032, Length=200, Percent_Identity=26.5, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320151, Length=255, Percent_Identity=28.6274509803922, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24641614, Length=194, Percent_Identity=27.8350515463918, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641612, Length=194, Percent_Identity=27.8350515463918, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281364648, Length=229, Percent_Identity=26.2008733624454, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582856, Length=229, Percent_Identity=26.2008733624454, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582854, Length=229, Percent_Identity=26.2008733624454, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28616; Mature: 28485

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILQAIRIFLFYLLLGTSSLLWCSLSFFVAPFLPFPKRYKFINVYWCRCALFLVKTILG
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
IDYKITGAEHVPDVPCVILSNHQSTWETFFLSAYFSPLSQVLKRELLYVPFFGWAMAMLR
CCEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
PIAIDRKNPKEALRQVASQGDELLKQGTWVLIFPEGTRVPHGQMGKFSRGGTALAVNAGL
HHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCC
PVLPIAHNAGKFWPREGWGKRPGTIEVVIGAPMYPEGTGPRAIAELNDRAQAWNEAAQRA
CEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MGSLPPVAENPEQQHA
HCCCCCCCCCCHHCCC
>Mature Secondary Structure 
SILQAIRIFLFYLLLGTSSLLWCSLSFFVAPFLPFPKRYKFINVYWCRCALFLVKTILG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
IDYKITGAEHVPDVPCVILSNHQSTWETFFLSAYFSPLSQVLKRELLYVPFFGWAMAMLR
CCEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
PIAIDRKNPKEALRQVASQGDELLKQGTWVLIFPEGTRVPHGQMGKFSRGGTALAVNAGL
HHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCC
PVLPIAHNAGKFWPREGWGKRPGTIEVVIGAPMYPEGTGPRAIAELNDRAQAWNEAAQRA
CEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MGSLPPVAENPEQQHA
HCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]