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The map label for this gene is gmhB [H]

Identifier: 162139702

GI number: 162139702

Start: 16962

End: 17489

Strand: Reverse

Name: gmhB [H]

Synonym: PSEEN0015

Alternate gene names: 162139702

Gene position: 17489-16962 (Counterclockwise)

Preceding gene: 104779330

Following gene: 104779328

Centisome position: 0.3

GC content: 61.93

Gene sequence:

>528_bases
TTGAAACTGCTGATTCTTGATCGAGACGGAGTGATCAACCACGACTCCGACGCCTACATCAAGTCGCTGGAGGAGTGGGT
TCCCATTCCCGGCTCGATCGAGGCCATCGCGCAGTTGAGCAAGGCGGGCTGGACGGTGGCTGTTGCCACCAACCAGTCCG
GCATTGCCCGTGGCTACTACCCGCTGGAAACCCTCGAGGCCATGCATGCGCGCCTGCGCGCGCTGGTGGCCGAGCTGGGC
GGCGAGGTTGGCTTGATCGTGCATTGCCCGCACGGCCCGGATGAAGGCTGCGATTGCCGCAAGCCCAAGCCCGGCATGCT
GCGGGCAATCGCCGAGCACTACCAGGTACCGCTGGCCGGCGTATGGTTCGTCGGCGACAGCAAAGGTGACCTGGAGGCGG
CCCTGGCCGTCGATGCACAACCCGTGTTGGTAAAAACCGGCAAGGGCGAAAGGACCCTGGAAAAAGGCGTCCCGGAAACT
ACACTGATTTTCGACGATCTGGCAGCCATCGCCAGAGAACTTATTTAA

Upstream 100 bases:

>100_bases
GCCGAGGACGCCAAGGTACGCGCCAACCGTTATGCCCTGCTCAGCCGCCTGCGCGGCCTGTTCCTGGGCGTGGCCGATAT
CTCGCTGCTGGGGTAAGTCG

Downstream 100 bases:

>100_bases
ATGAGTGCGCCAGGAACGGCGCACTTTTCATTAGGCGGGCACGCCCCGCAACGGTACATGCCACTATGTCGATCCTGCAG
GCGATCAGAATCTTTCTTTT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MKLLILDRDGVINHDSDAYIKSLEEWVPIPGSIEAIAQLSKAGWTVAVATNQSGIARGYYPLETLEAMHARLRALVAELG
GEVGLIVHCPHGPDEGCDCRKPKPGMLRAIAEHYQVPLAGVWFVGDSKGDLEAALAVDAQPVLVKTGKGERTLEKGVPET
TLIFDDLAAIARELI

Sequences:

>Translated_175_residues
MKLLILDRDGVINHDSDAYIKSLEEWVPIPGSIEAIAQLSKAGWTVAVATNQSGIARGYYPLETLEAMHARLRALVAELG
GEVGLIVHCPHGPDEGCDCRKPKPGMLRAIAEHYQVPLAGVWFVGDSKGDLEAALAVDAQPVLVKTGKGERTLEKGVPET
TLIFDDLAAIARELI
>Mature_175_residues
MKLLILDRDGVINHDSDAYIKSLEEWVPIPGSIEAIAQLSKAGWTVAVATNQSGIARGYYPLETLEAMHARLRALVAELG
GEVGLIVHCPHGPDEGCDCRKPKPGMLRAIAEHYQVPLAGVWFVGDSKGDLEAALAVDAQPVLVKTGKGERTLEKGVPET
TLIFDDLAAIARELI

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=153, Percent_Identity=37.2549019607843, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI87082027, Length=135, Percent_Identity=28.1481481481481, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 18803; Mature: 18803

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLILDRDGVINHDSDAYIKSLEEWVPIPGSIEAIAQLSKAGWTVAVATNQSGIARGYY
CEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCC
PLETLEAMHARLRALVAELGGEVGLIVHCPHGPDEGCDCRKPKPGMLRAIAEHYQVPLAG
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEE
VWFVGDSKGDLEAALAVDAQPVLVKTGKGERTLEKGVPETTLIFDDLAAIARELI
EEEEECCCCCCEEEEEECCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLLILDRDGVINHDSDAYIKSLEEWVPIPGSIEAIAQLSKAGWTVAVATNQSGIARGYY
CEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCC
PLETLEAMHARLRALVAELGGEVGLIVHCPHGPDEGCDCRKPKPGMLRAIAEHYQVPLAG
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEE
VWFVGDSKGDLEAALAVDAQPVLVKTGKGERTLEKGVPETTLIFDDLAAIARELI
EEEEECCCCCCEEEEEECCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 12101286 [H]