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The map label for this gene is glpR [H]

Identifier: 94986271

GI number: 94986271

Start: 2287455

End: 2288267

Strand: Reverse

Name: glpR [H]

Synonym: Dgeo_2172

Alternate gene names: 94986271

Gene position: 2288267-2287455 (Counterclockwise)

Preceding gene: 94986275

Following gene: 94986270

Centisome position: 92.75

GC content: 69.5

Gene sequence:

>813_bases
ATGACTGCCCCGCTTGCAGAGGAACGCCTCAGCCGCATCCTCGACCTGCTGGCTCGCCACGGGACGGTGCGCACCACAGC
GATCACGGAACACCTGGGGGTGAGCGGTGCGACGGCGCGGCGGGACCTCGATGTGTTGGCGCGGCGTGGCCTGATCCGCA
AGGTGCATGGGGGCGCGGCGCTTGTCAGCCAGGATCAGCAGTACCGTGACCGCCAGCAGACCGAACAGGGGGGCAAAGCC
CGCCTAGCCGAGGCCGCGCTCACCCTGCTGCGCCCCGGCCAGACGGTCTATCTCGATGCGGGCACCACGGCCCGGCATGT
GGCGGAGGCGTTGCGGCGCTTGCCGGCCCTCACCCGGACCCTGCGCGTCGTGACGCACGCCATCGACGTGGCCTACGAAC
TCAACGGCGAGTGTCCACTGTATGTGGTCGGCGGTGAGGTGTACGGCTCCACCTACAGCCTGACCGGCCCCGACGCGCTC
GCAACGGTGGAGCGCTATGCCTACGATGTTTTTCTGGTGGGATGCACCAGCATCGACCCGGAGCGCGGCCTGACGAACAG
CAACCTGATCGAGGCGCAGCAGAAGGCGGCCATCCTGCGCCGAGCTCGCCGCAGCATCCTGATCGCCGACCACAGCAAGT
GGGGCCACAGCGGCTTTGTGACCTTTGCGAGCCTGGGGGATGTCCGTGCCTGGGTGACCGACTGGGCGCCCCCCGGTGCC
CGGCAGACCTTCGAGGCAGCGGGCGTGCAAGTGGTAGAGGCGCAGCCCGCAGCAGCGGAGGAGCGGGTGGCTCGGGTTCC
GGCGCTCCCCTGA

Upstream 100 bases:

>100_bases
TGCTCGCTGGAGGACATGGCTTGGTTGGAGAGCTGGCTGATTGGGTTCTGTTGAGCAGTTTTGAGCATTTTTTCTGGGCG
CATGAGGTACCATCAAACAG

Downstream 100 bases:

>100_bases
CCCTCCCCAGCTCCAGGCTGGTGGCTGAGTACTGGCGGTTGGGTACTGGCGGCTTCTGCAGGGCCGATGCTTTAAGCCTT
GCTCAAGCCGCCTCATGACG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTAPLAEERLSRILDLLARHGTVRTTAITEHLGVSGATARRDLDVLARRGLIRKVHGGAALVSQDQQYRDRQQTEQGGKA
RLAEAALTLLRPGQTVYLDAGTTARHVAEALRRLPALTRTLRVVTHAIDVAYELNGECPLYVVGGEVYGSTYSLTGPDAL
ATVERYAYDVFLVGCTSIDPERGLTNSNLIEAQQKAAILRRARRSILIADHSKWGHSGFVTFASLGDVRAWVTDWAPPGA
RQTFEAAGVQVVEAQPAAAEERVARVPALP

Sequences:

>Translated_270_residues
MTAPLAEERLSRILDLLARHGTVRTTAITEHLGVSGATARRDLDVLARRGLIRKVHGGAALVSQDQQYRDRQQTEQGGKA
RLAEAALTLLRPGQTVYLDAGTTARHVAEALRRLPALTRTLRVVTHAIDVAYELNGECPLYVVGGEVYGSTYSLTGPDAL
ATVERYAYDVFLVGCTSIDPERGLTNSNLIEAQQKAAILRRARRSILIADHSKWGHSGFVTFASLGDVRAWVTDWAPPGA
RQTFEAAGVQVVEAQPAAAEERVARVPALP
>Mature_269_residues
TAPLAEERLSRILDLLARHGTVRTTAITEHLGVSGATARRDLDVLARRGLIRKVHGGAALVSQDQQYRDRQQTEQGGKAR
LAEAALTLLRPGQTVYLDAGTTARHVAEALRRLPALTRTLRVVTHAIDVAYELNGECPLYVVGGEVYGSTYSLTGPDALA
TVERYAYDVFLVGCTSIDPERGLTNSNLIEAQQKAAILRRARRSILIADHSKWGHSGFVTFASLGDVRAWVTDWAPPGAR
QTFEAAGVQVVEAQPAAAEERVARVPALP

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=235, Percent_Identity=33.1914893617021, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87082344, Length=257, Percent_Identity=29.5719844357977, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=30.1310043668122, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=27.8225806451613, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=27.5590551181102, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788069, Length=237, Percent_Identity=26.1603375527426, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790753, Length=254, Percent_Identity=28.740157480315, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787540, Length=208, Percent_Identity=25.9615384615385, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI226510968, Length=236, Percent_Identity=28.3898305084746, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1790635, Length=251, Percent_Identity=25.8964143426295, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787063, Length=242, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29238; Mature: 29106

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPLAEERLSRILDLLARHGTVRTTAITEHLGVSGATARRDLDVLARRGLIRKVHGGAA
CCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHCCCHH
LVSQDQQYRDRQQTEQGGKARLAEAALTLLRPGQTVYLDAGTTARHVAEALRRLPALTRT
HHCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LRVVTHAIDVAYELNGECPLYVVGGEVYGSTYSLTGPDALATVERYAYDVFLVGCTSIDP
HHHHHHHHHHHEEECCCCCEEEECCEEECCEEECCCCHHHHHHHHHHEEEEEEEECCCCC
ERGLTNSNLIEAQQKAAILRRARRSILIADHSKWGHSGFVTFASLGDVRAWVTDWAPPGA
CCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEHHCCHHHHHHCCCCCCC
RQTFEAAGVQVVEAQPAAAEERVARVPALP
CHHHHHCCEEEEECCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TAPLAEERLSRILDLLARHGTVRTTAITEHLGVSGATARRDLDVLARRGLIRKVHGGAA
CCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHCCCHH
LVSQDQQYRDRQQTEQGGKARLAEAALTLLRPGQTVYLDAGTTARHVAEALRRLPALTRT
HHCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LRVVTHAIDVAYELNGECPLYVVGGEVYGSTYSLTGPDALATVERYAYDVFLVGCTSIDP
HHHHHHHHHHHEEECCCCCEEEECCEEECCEEECCCCHHHHHHHHHHEEEEEEEECCCCC
ERGLTNSNLIEAQQKAAILRRARRSILIADHSKWGHSGFVTFASLGDVRAWVTDWAPPGA
CCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEHHCCHHHHHHCCCCCCC
RQTFEAAGVQVVEAQPAAAEERVARVPALP
CHHHHHCCEEEEECCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]