BacMap

Definition	Deinococcus geothermalis DSM 11300, complete genome.
Accession	NC_008025
Length	2,467,205

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The map label for this gene is ftsH [H]

Identifier: 94986174

GI number: 94986174

Start: 2183992

End: 2185857

Strand: Reverse

Name: ftsH [H]

Synonym: Dgeo_2075

Alternate gene names: 94986174

Gene position: 2185857-2183992 (Counterclockwise)

Preceding gene: 94986179

Following gene: 94986173

Centisome position: 88.6

GC content: 67.42

Gene sequence:

>1866_bases
ATGAAACGCGCCTCGTGGGGCTGGGGCTTGGCCGCCGCTGTGGTCTTGCTGCTGCTCCTGATCAACGTGGCGAGCCCGCG
TGGGCACAGCGGGGAACTGTCCCTGAATGACTTCACGAATGCCCTGCAGACCCGGCAGGTGCAGAGTGCGACTGTGCAGT
TCCAGAACAACACCGCGCTGCTCACCGGCACCCTGAAGAGTGGCGAGCCCTACACCACGCGCACGCTCGCCTCCGATCCC
GCCATCCAGATGGACCGGCTCCAAGCGGCCGGAGTGGACGTCACCTACGCACCTGCCGCTCGGCTGAACTTCCTCACTTT
GCTGAGCGGGCTGCTGACCCTGCTGCTGATTGTGGGCCTGTTGCTGCTGCTGTTTCGCCAGCGAGGGGCGGGCAGCACTG
ACGCGGCGGGGACGTTTGGGAAATCGCGGGCGGCGGTGATCAGCGAGGGACAGGTGAAACTCACCTTCCAGGACGTGGCG
GGCTGCGACGAAGCCAAGCAGGACCTGCAGGAAGTCGTCGACTTCCTGCGTCATCCCGAGCGCTACCACCAGCTCGGCGC
CCGCATTCCCCACGGCGTTCTTCTCGTCGGCCCCCCCGGCTCCGGCAAGACCCTCCTTGCCAAAGCGGTCGCTGGTGAAG
CCAAAGTCCCCTACTTCTCCATCAGTGGCAGTGACTTCGTCGAAATGTTCGTCGGCGTCGGCGCGGCCCGCGTCCGCGAC
CTGTTTGAACAGGCCAGAAAGAGTGCGCCCTGCATCGTCTTCATCGACGAGATCGATGCCGTGGGCCGCAAACGCGGCGT
CAATCTCCAAGGCGGCAATGACGAACGCGAACAGACCCTCAACCAGTTGCTGGTCGAGATGGACGGCTTCTCCTCTGGCC
AGGAGGTGATCATCCTGGCCGCCACCAACCGCCCCGACGTGTTGGACGCCGCCTTGCTGCGTCCGGGCCGCTTCGACCGC
CAGGTGGTGGTGGACGCCCCCGACGTGCGGGGGCGCGAGATGATCCTCAGGATTCATGCCCGCAAAAAACCCCTGGACGC
CTCGGTGGACCTGGGCTTGATTGCCCGCCGGACAGCTGGGATGGTGGGAGCAGAGCTGGAAAACCTCTTGAACGAGGCGG
CGCTGGGGGCCGCGCGGGCGGGACGGTCCCGGATTGTGATGCGCGATGTGGAGGAGGCGCGCGACCGGGTGCTGATGGGC
CCGGAGCGCCGCTCGCTGGTGGTGCGGGAAGCCGACCGCAAGGTTACCGCCTACCACGAGGTCGGCCATGCCCTCGCCGC
CCAGCTCCTCCCGCACGCCGACAAGGCGCACAAGCTGACCATCGTCCCGCGGGGACGTTCGCTGGGGTCGGCGCTCTACA
CGCCGGAAGACCGGATGCACCTCACGCGCGCTGCGCTGCTCGACCGCATCTGCGTGGCGCTGGCCGGGCACGCCGCCGAG
GAGGTCGTGTACGGCGAGGTCACGACCGGTGCACAGAATGACTTCCAGCAGGCGACCCACCTCGCCCGCCGCATGGTGAC
CGAGTGGGGCATGAGCGAGGTGGGTCAGCTCGCGCTCGCCCAGGAGAGTGGCAGCTATCTGGGCTACGGTCCCCAGCAGG
GCAGCTACAGCGATCACACCGCCGAGCGCATCGACGCCGAACTCGCGCGCATCCTCAACGGGCAGTACGAGCGGGCAGTT
GCGCTGCTCACCGAGCACGTCCACGTCCTGCACCGCCTGACCGACGCGCTGATGGCACGCGAATCCCTGACGGGTGAGGA
CGTGCAGACAGTTTTGGCGGGAGGAACACTGGAGGAAACTCCTGCTGCCCCCGAGGGCGACGAGGGTGCCGCTCCGCAGG
CCGGCCTGACCCCTACCCCGGCGTGA

Upstream 100 bases:

>100_bases
CTCACATCGCTACCGGAATTCCAGAGTTCGGCGTGCCGGGCGGCATAGACTGAGCCATGGCGACAACTGGAGCTGGAGGG
AACACCGGAGGGAGAGAGGG

Downstream 100 bases:

>100_bases
TGGGCAACCTAGGCTGAACGTTTCCCCATGACTTCCCGGGCGCGGCCCTTTAGGGTGAAAGGTATGTTTCGCACGCTCAG
CCTGCTGACCTCCGCGCTGC

Product: ATP-dependent metalloprotease FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MKRASWGWGLAAAVVLLLLLINVASPRGHSGELSLNDFTNALQTRQVQSATVQFQNNTALLTGTLKSGEPYTTRTLASDP
AIQMDRLQAAGVDVTYAPAARLNFLTLLSGLLTLLLIVGLLLLLFRQRGAGSTDAAGTFGKSRAAVISEGQVKLTFQDVA
GCDEAKQDLQEVVDFLRHPERYHQLGARIPHGVLLVGPPGSGKTLLAKAVAGEAKVPYFSISGSDFVEMFVGVGAARVRD
LFEQARKSAPCIVFIDEIDAVGRKRGVNLQGGNDEREQTLNQLLVEMDGFSSGQEVIILAATNRPDVLDAALLRPGRFDR
QVVVDAPDVRGREMILRIHARKKPLDASVDLGLIARRTAGMVGAELENLLNEAALGAARAGRSRIVMRDVEEARDRVLMG
PERRSLVVREADRKVTAYHEVGHALAAQLLPHADKAHKLTIVPRGRSLGSALYTPEDRMHLTRAALLDRICVALAGHAAE
EVVYGEVTTGAQNDFQQATHLARRMVTEWGMSEVGQLALAQESGSYLGYGPQQGSYSDHTAERIDAELARILNGQYERAV
ALLTEHVHVLHRLTDALMARESLTGEDVQTVLAGGTLEETPAAPEGDEGAAPQAGLTPTPA

Sequences:

>Translated_621_residues
MKRASWGWGLAAAVVLLLLLINVASPRGHSGELSLNDFTNALQTRQVQSATVQFQNNTALLTGTLKSGEPYTTRTLASDP
AIQMDRLQAAGVDVTYAPAARLNFLTLLSGLLTLLLIVGLLLLLFRQRGAGSTDAAGTFGKSRAAVISEGQVKLTFQDVA
GCDEAKQDLQEVVDFLRHPERYHQLGARIPHGVLLVGPPGSGKTLLAKAVAGEAKVPYFSISGSDFVEMFVGVGAARVRD
LFEQARKSAPCIVFIDEIDAVGRKRGVNLQGGNDEREQTLNQLLVEMDGFSSGQEVIILAATNRPDVLDAALLRPGRFDR
QVVVDAPDVRGREMILRIHARKKPLDASVDLGLIARRTAGMVGAELENLLNEAALGAARAGRSRIVMRDVEEARDRVLMG
PERRSLVVREADRKVTAYHEVGHALAAQLLPHADKAHKLTIVPRGRSLGSALYTPEDRMHLTRAALLDRICVALAGHAAE
EVVYGEVTTGAQNDFQQATHLARRMVTEWGMSEVGQLALAQESGSYLGYGPQQGSYSDHTAERIDAELARILNGQYERAV
ALLTEHVHVLHRLTDALMARESLTGEDVQTVLAGGTLEETPAAPEGDEGAAPQAGLTPTPA
>Mature_621_residues
MKRASWGWGLAAAVVLLLLLINVASPRGHSGELSLNDFTNALQTRQVQSATVQFQNNTALLTGTLKSGEPYTTRTLASDP
AIQMDRLQAAGVDVTYAPAARLNFLTLLSGLLTLLLIVGLLLLLFRQRGAGSTDAAGTFGKSRAAVISEGQVKLTFQDVA
GCDEAKQDLQEVVDFLRHPERYHQLGARIPHGVLLVGPPGSGKTLLAKAVAGEAKVPYFSISGSDFVEMFVGVGAARVRD
LFEQARKSAPCIVFIDEIDAVGRKRGVNLQGGNDEREQTLNQLLVEMDGFSSGQEVIILAATNRPDVLDAALLRPGRFDR
QVVVDAPDVRGREMILRIHARKKPLDASVDLGLIARRTAGMVGAELENLLNEAALGAARAGRSRIVMRDVEEARDRVLMG
PERRSLVVREADRKVTAYHEVGHALAAQLLPHADKAHKLTIVPRGRSLGSALYTPEDRMHLTRAALLDRICVALAGHAAE
EVVYGEVTTGAQNDFQQATHLARRMVTEWGMSEVGQLALAQESGSYLGYGPQQGSYSDHTAERIDAELARILNGQYERAV
ALLTEHVHVLHRLTDALMARESLTGEDVQTVLAGGTLEETPAAPEGDEGAAPQAGLTPTPA

Specific function: Degrades preferentially unfolded substrates in a processive, ATP-dependent manner, usually after hydrophobic residues [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane (Probable); Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=534, Percent_Identity=44.9438202247191, Blast_Score=447, Evalue=1e-125,
Organism=Homo sapiens, GI21327685, Length=499, Percent_Identity=46.4929859719439, Blast_Score=420, Evalue=1e-117,
Organism=Homo sapiens, GI7657689, Length=499, Percent_Identity=46.4929859719439, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI4507173, Length=604, Percent_Identity=37.7483443708609, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI4506209, Length=251, Percent_Identity=43.0278884462151, Blast_Score=209, Evalue=6e-54,
Organism=Homo sapiens, GI24497435, Length=257, Percent_Identity=39.6887159533074, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI6005942, Length=233, Percent_Identity=41.2017167381974, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI40806173, Length=302, Percent_Identity=41.3907284768212, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI24430151, Length=245, Percent_Identity=40, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI21361144, Length=238, Percent_Identity=40.7563025210084, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI89064750, Length=257, Percent_Identity=39.2996108949416, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI5729991, Length=257, Percent_Identity=39.2996108949416, Blast_Score=186, Evalue=6e-47,
Organism=Homo sapiens, GI24430155, Length=257, Percent_Identity=39.2996108949416, Blast_Score=186, Evalue=7e-47,
Organism=Homo sapiens, GI195539395, Length=245, Percent_Identity=39.1836734693878, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI45643125, Length=244, Percent_Identity=42.2131147540984, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI45643123, Length=244, Percent_Identity=42.2131147540984, Blast_Score=182, Evalue=8e-46,
Organism=Homo sapiens, GI157671927, Length=224, Percent_Identity=41.0714285714286, Blast_Score=176, Evalue=7e-44,
Organism=Homo sapiens, GI229577436, Length=240, Percent_Identity=38.75, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI4505725, Length=225, Percent_Identity=38.6666666666667, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI194018488, Length=230, Percent_Identity=40.4347826086956, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI5901990, Length=233, Percent_Identity=41.2017167381974, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI153792536, Length=232, Percent_Identity=37.9310344827586, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI24497618, Length=234, Percent_Identity=38.4615384615385, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI14149767, Length=238, Percent_Identity=38.655462184874, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI62177112, Length=238, Percent_Identity=38.655462184874, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI11875211, Length=240, Percent_Identity=40.8333333333333, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI40806170, Length=240, Percent_Identity=40.8333333333333, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI226371754, Length=250, Percent_Identity=36.4, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI7019569, Length=251, Percent_Identity=33.4661354581673, Blast_Score=130, Evalue=5e-30,
Organism=Homo sapiens, GI156564401, Length=212, Percent_Identity=38.2075471698113, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI17865802, Length=253, Percent_Identity=34.7826086956522, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI310125282, Length=212, Percent_Identity=37.7358490566038, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI31742536, Length=231, Percent_Identity=31.1688311688312, Blast_Score=126, Evalue=8e-29,
Organism=Homo sapiens, GI112789543, Length=231, Percent_Identity=31.1688311688312, Blast_Score=126, Evalue=8e-29,
Organism=Homo sapiens, GI310125280, Length=212, Percent_Identity=37.7358490566038, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI31377644, Length=263, Percent_Identity=31.5589353612167, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI64084766, Length=240, Percent_Identity=27.5, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI75677353, Length=194, Percent_Identity=33.5051546391753, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI116292174, Length=248, Percent_Identity=29.8387096774194, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI283436220, Length=198, Percent_Identity=31.3131313131313, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI283436222, Length=198, Percent_Identity=31.3131313131313, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI283436224, Length=198, Percent_Identity=31.3131313131313, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789568, Length=620, Percent_Identity=48.0645161290323, Blast_Score=569, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI71994521, Length=455, Percent_Identity=47.4725274725275, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17554264, Length=450, Percent_Identity=46.8888888888889, Blast_Score=373, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI115534323, Length=458, Percent_Identity=45.1965065502183, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17563248, Length=253, Percent_Identity=44.2687747035573, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17554786, Length=257, Percent_Identity=40.4669260700389, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI25144278, Length=257, Percent_Identity=40.4669260700389, Blast_Score=208, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI25144281, Length=257, Percent_Identity=40.4669260700389, Blast_Score=208, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI17532375, Length=268, Percent_Identity=39.5522388059701, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17563250, Length=245, Percent_Identity=42.4489795918367, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17505546, Length=252, Percent_Identity=42.4603174603175, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17531535, Length=268, Percent_Identity=39.1791044776119, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17508701, Length=239, Percent_Identity=41.0041841004184, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71987364, Length=245, Percent_Identity=39.5918367346939, Blast_Score=185, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI71987372, Length=245, Percent_Identity=39.5918367346939, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17508053, Length=229, Percent_Identity=42.7947598253275, Blast_Score=182, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17554784, Length=246, Percent_Identity=39.4308943089431, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI25153574, Length=248, Percent_Identity=39.5161290322581, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17537217, Length=275, Percent_Identity=38.9090909090909, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI193209502, Length=227, Percent_Identity=39.2070484581498, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI133931034, Length=281, Percent_Identity=38.0782918149466, Blast_Score=152, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI193206116, Length=281, Percent_Identity=38.0782918149466, Blast_Score=152, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI193206114, Length=281, Percent_Identity=38.0782918149466, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17562804, Length=229, Percent_Identity=37.5545851528384, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25146157, Length=245, Percent_Identity=38.7755102040816, Blast_Score=142, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17570397, Length=163, Percent_Identity=47.239263803681, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32566590, Length=163, Percent_Identity=47.239263803681, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI133901658, Length=216, Percent_Identity=37.962962962963, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI133901662, Length=209, Percent_Identity=38.2775119617225, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI86561515, Length=244, Percent_Identity=36.0655737704918, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17541226, Length=231, Percent_Identity=35.4978354978355, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17541224, Length=231, Percent_Identity=35.4978354978355, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32563584, Length=243, Percent_Identity=35.3909465020576, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17508421, Length=243, Percent_Identity=35.3909465020576, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17560432, Length=274, Percent_Identity=32.4817518248175, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71990294, Length=200, Percent_Identity=31, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323736, Length=490, Percent_Identity=46.9387755102041, Blast_Score=433, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6320854, Length=522, Percent_Identity=44.0613026819923, Blast_Score=430, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6325281, Length=517, Percent_Identity=43.5203094777563, Blast_Score=404, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6322704, Length=262, Percent_Identity=41.9847328244275, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6321390, Length=245, Percent_Identity=40.4081632653061, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320077, Length=229, Percent_Identity=41.9213973799127, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320197, Length=245, Percent_Identity=38.7755102040816, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324691, Length=239, Percent_Identity=41.0041841004184, Blast_Score=187, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6320602, Length=242, Percent_Identity=42.1487603305785, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6324833, Length=248, Percent_Identity=39.1129032258064, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322994, Length=233, Percent_Identity=40.7725321888412, Blast_Score=168, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6324000, Length=293, Percent_Identity=35.8361774744027, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6323429, Length=245, Percent_Identity=40.4081632653061, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6322651, Length=241, Percent_Identity=37.344398340249, Blast_Score=157, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6321709, Length=264, Percent_Identity=37.1212121212121, Blast_Score=157, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6321465, Length=240, Percent_Identity=37.5, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6325431, Length=271, Percent_Identity=34.3173431734317, Blast_Score=138, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6325183, Length=258, Percent_Identity=35.2713178294574, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6319554, Length=210, Percent_Identity=34.7619047619048, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320887, Length=249, Percent_Identity=33.7349397590361, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320583, Length=176, Percent_Identity=31.25, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28574878, Length=628, Percent_Identity=39.4904458598726, Blast_Score=446, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24665814, Length=628, Percent_Identity=39.4904458598726, Blast_Score=445, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24658770, Length=492, Percent_Identity=46.3414634146341, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24639391, Length=469, Percent_Identity=43.7100213219616, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI45554047, Length=189, Percent_Identity=53.4391534391534, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI17137560, Length=260, Percent_Identity=39.2307692307692, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI161076488, Length=260, Percent_Identity=39.2307692307692, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI161076486, Length=260, Percent_Identity=39.2307692307692, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI17137738, Length=251, Percent_Identity=43.0278884462151, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24651451, Length=257, Percent_Identity=40.8560311284047, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI19920408, Length=257, Percent_Identity=39.6887159533074, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24649446, Length=245, Percent_Identity=40.4081632653061, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17738151, Length=239, Percent_Identity=40.5857740585774, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI18860063, Length=240, Percent_Identity=40.4166666666667, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI19921202, Length=225, Percent_Identity=41.7777777777778, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=39.5918367346939, Blast_Score=182, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24652279, Length=206, Percent_Identity=42.2330097087379, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI281361487, Length=240, Percent_Identity=39.5833333333333, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24660075, Length=229, Percent_Identity=42.3580786026201, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI281365776, Length=229, Percent_Identity=42.3580786026201, Blast_Score=175, Evalue=7e-44,
Organism=Drosophila melanogaster, GI45552965, Length=229, Percent_Identity=42.3580786026201, Blast_Score=175, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24663015, Length=241, Percent_Identity=36.9294605809129, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24656825, Length=241, Percent_Identity=39.4190871369295, Blast_Score=169, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24656820, Length=241, Percent_Identity=39.4190871369295, Blast_Score=169, Evalue=6e-42,
Organism=Drosophila melanogaster, GI281363136, Length=254, Percent_Identity=38.9763779527559, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI78707192, Length=254, Percent_Identity=38.9763779527559, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24644145, Length=233, Percent_Identity=39.0557939914163, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21355121, Length=203, Percent_Identity=37.9310344827586, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281360144, Length=267, Percent_Identity=35.2059925093633, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281360140, Length=267, Percent_Identity=35.2059925093633, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281360136, Length=267, Percent_Identity=35.2059925093633, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24644411, Length=267, Percent_Identity=35.2059925093633, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281360142, Length=232, Percent_Identity=37.5, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI21357333, Length=232, Percent_Identity=37.5, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360146, Length=232, Percent_Identity=37.5, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281360138, Length=232, Percent_Identity=37.5, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI18859657, Length=233, Percent_Identity=37.7682403433476, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI28571849, Length=240, Percent_Identity=40, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28571847, Length=240, Percent_Identity=40, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24581396, Length=236, Percent_Identity=38.135593220339, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17864540, Length=238, Percent_Identity=34.8739495798319, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI28573010, Length=241, Percent_Identity=34.4398340248963, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI20129529, Length=241, Percent_Identity=33.6099585062241, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI20129423, Length=259, Percent_Identity=30.5019305019305, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24639486, Length=200, Percent_Identity=34.5, Blast_Score=99, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 66772; Mature: 66772

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00142 ZINC_PROTEASE ; PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRASWGWGLAAAVVLLLLLINVASPRGHSGELSLNDFTNALQTRQVQSATVQFQNNTAL
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHEEEEECCEEE
LTGTLKSGEPYTTRTLASDPAIQMDRLQAAGVDVTYAPAARLNFLTLLSGLLTLLLIVGL
EEEECCCCCCCEEEECCCCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
LLLLFRQRGAGSTDAAGTFGKSRAAVISEGQVKLTFQDVAGCDEAKQDLQEVVDFLRHPE
HHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEEEHHHCCCHHHHHHHHHHHHHHHCCH
RYHQLGARIPHGVLLVGPPGSGKTLLAKAVAGEAKVPYFSISGSDFVEMFVGVGAARVRD
HHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCHHHHHH
LFEQARKSAPCIVFIDEIDAVGRKRGVNLQGGNDEREQTLNQLLVEMDGFSSGQEVIILA
HHHHHHHCCCEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEE
ATNRPDVLDAALLRPGRFDRQVVVDAPDVRGREMILRIHARKKPLDASVDLGLIARRTAG
ECCCCCHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
MVGAELENLLNEAALGAARAGRSRIVMRDVEEARDRVLMGPERRSLVVREADRKVTAYHE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCHHHEEEECCCCHHHHHHH
VGHALAAQLLPHADKAHKLTIVPRGRSLGSALYTPEDRMHLTRAALLDRICVALAGHAAE
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
EVVYGEVTTGAQNDFQQATHLARRMVTEWGMSEVGQLALAQESGSYLGYGPQQGSYSDHT
HEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
AERIDAELARILNGQYERAVALLTEHVHVLHRLTDALMARESLTGEDVQTVLAGGTLEET
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC
PAAPEGDEGAAPQAGLTPTPA
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRASWGWGLAAAVVLLLLLINVASPRGHSGELSLNDFTNALQTRQVQSATVQFQNNTAL
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHEEEEECCEEE
LTGTLKSGEPYTTRTLASDPAIQMDRLQAAGVDVTYAPAARLNFLTLLSGLLTLLLIVGL
EEEECCCCCCCEEEECCCCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
LLLLFRQRGAGSTDAAGTFGKSRAAVISEGQVKLTFQDVAGCDEAKQDLQEVVDFLRHPE
HHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEEEHHHCCCHHHHHHHHHHHHHHHCCH
RYHQLGARIPHGVLLVGPPGSGKTLLAKAVAGEAKVPYFSISGSDFVEMFVGVGAARVRD
HHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCHHHHHH
LFEQARKSAPCIVFIDEIDAVGRKRGVNLQGGNDEREQTLNQLLVEMDGFSSGQEVIILA
HHHHHHHCCCEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEE
ATNRPDVLDAALLRPGRFDRQVVVDAPDVRGREMILRIHARKKPLDASVDLGLIARRTAG
ECCCCCHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
MVGAELENLLNEAALGAARAGRSRIVMRDVEEARDRVLMGPERRSLVVREADRKVTAYHE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCHHHEEEECCCCHHHHHHH
VGHALAAQLLPHADKAHKLTIVPRGRSLGSALYTPEDRMHLTRAALLDRICVALAGHAAE
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
EVVYGEVTTGAQNDFQQATHLARRMVTEWGMSEVGQLALAQESGSYLGYGPQQGSYSDHT
HEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
AERIDAELARILNGQYERAVALLTEHVHVLHRLTDALMARESLTGEDVQTVLAGGTLEET
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC
PAAPEGDEGAAPQAGLTPTPA
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10788805; 10377389 [H]