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The map label for this gene is aspC [H]

Identifier: 94986168

GI number: 94986168

Start: 2174647

End: 2175774

Strand: Reverse

Name: aspC [H]

Synonym: Dgeo_2069

Alternate gene names: 94986168

Gene position: 2175774-2174647 (Counterclockwise)

Preceding gene: 94986171

Following gene: 94986167

Centisome position: 88.19

GC content: 69.06

Gene sequence:

>1128_bases
ATGCCTGAACTGCTGCCGCGTGCCCGCTCGTCCCAGGAGAGCATCTTTGCCCGTATGAGCCGCCTCGCTGCGCAGTACGG
CGCGATCAACCTGGGGCAGGGCTTCCCCTCTGACGCCCCCCCCGCTTTCTTGCTGGAGGCGGCGCGGCGAGCGGTGGGCA
CGGCAGACCAGTACGCCCCACCGGCGGGCCTCCCCGCCCTGCGGGACGCGCTGGGCGCTGACCTGGGCGTGGACGGCGCG
GACTTGGTGGTCACAACGGGCGCAACGGAAGCGCTGGGCCTTCTGGCGCAGGCCCTCTACGGCCCTGGCGACGAGGTGCT
CATGTTTGAACCCGTGTTCGACATCTACCTGCCGCAGGCGCGGCTGGCGGGGGCAACGCCCGTCACTGTTCCCCTGCGGC
TGGAGGGAGAAGGCAGCTGGTCACTGGATCTGGATGAACTGCGCGCCGCCGTCACGCCCCGCACGCGAGCGCTCCTGCTC
AACAGTCCGCACAACCCCACCGGCCGCATCTTCACGCGCGAGGAACTCGAAGCCCTGGTTGCTCTCGCCCGCCAGCACGA
CCTCTGGCTGATCTCTGACGAGGTGTACGATGAGCTGTATTTCGGGGAGCCTCCCCTCTCGCTGCGCACGCTGGCCCCCG
AGCGGACCTTCACGGTGGGCAGCGCGGGCAAAAGGCTGGAGGCCACCGGCTGGCGTGTCGGCTGGGTGGCTTGCCCACCG
GGTTTCGCGGGGAATCTGGCGGGACTGCGGCAGGTGGCCTCCTTTTGCGCGCCCACGCCCTTTCAGGCAGCGGTAGCGGC
GGCGCTTCCCATTGCCCGGGAGACCGGTTTCTATGGGGGCCTGCGCGAGGCGTACGTGGCGCGGCTTGACCTGCTGGCGG
GCGGCCTGCGTGAGCTTGGTGCCACGGTCTTTCGGCCCAGCGGCACCTACTTCCTGATGGCCTGCCGTCCCGGCTGGGAA
GCTGAAACGCTGGTGAAGAGGGCAGGTGTGGCGATGATTCCTGCTGAAGCGTTTGCGGCCAACGAAGCGCCCCCACCCGG
GCTGTTGCGCCTGGCCTTTTGCAAATCGCAGGCCGAGCTGGAAGAAGCGTTGGTGCGCCTTGCCCGCTGGGAGAAGGCCG
GAGGATGA

Upstream 100 bases:

>100_bases
GCCCAGGTCCGTGGCTGCTGGCGCTTGAGGCTGTCGCCTTCGCTCGCCTGCCTAAGCGGCCCCGCTTGCCCAGTCCACCT
GATGCGCCCAGACTGCCCCT

Downstream 100 bases:

>100_bases
ACGAAAGGACAAAGCCAGACTCGGAAGGAGTAAAGGTGTAGGTTGTCCGGTTTGACTATCCTCAACCTATGAAGAACGCT
CTGCTCGGTTTCTTGGCACT

Product: aminotransferase, class I and II

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MPELLPRARSSQESIFARMSRLAAQYGAINLGQGFPSDAPPAFLLEAARRAVGTADQYAPPAGLPALRDALGADLGVDGA
DLVVTTGATEALGLLAQALYGPGDEVLMFEPVFDIYLPQARLAGATPVTVPLRLEGEGSWSLDLDELRAAVTPRTRALLL
NSPHNPTGRIFTREELEALVALARQHDLWLISDEVYDELYFGEPPLSLRTLAPERTFTVGSAGKRLEATGWRVGWVACPP
GFAGNLAGLRQVASFCAPTPFQAAVAAALPIARETGFYGGLREAYVARLDLLAGGLRELGATVFRPSGTYFLMACRPGWE
AETLVKRAGVAMIPAEAFAANEAPPPGLLRLAFCKSQAELEEALVRLARWEKAGG

Sequences:

>Translated_375_residues
MPELLPRARSSQESIFARMSRLAAQYGAINLGQGFPSDAPPAFLLEAARRAVGTADQYAPPAGLPALRDALGADLGVDGA
DLVVTTGATEALGLLAQALYGPGDEVLMFEPVFDIYLPQARLAGATPVTVPLRLEGEGSWSLDLDELRAAVTPRTRALLL
NSPHNPTGRIFTREELEALVALARQHDLWLISDEVYDELYFGEPPLSLRTLAPERTFTVGSAGKRLEATGWRVGWVACPP
GFAGNLAGLRQVASFCAPTPFQAAVAAALPIARETGFYGGLREAYVARLDLLAGGLRELGATVFRPSGTYFLMACRPGWE
AETLVKRAGVAMIPAEAFAANEAPPPGLLRLAFCKSQAELEEALVRLARWEKAGG
>Mature_374_residues
PELLPRARSSQESIFARMSRLAAQYGAINLGQGFPSDAPPAFLLEAARRAVGTADQYAPPAGLPALRDALGADLGVDGAD
LVVTTGATEALGLLAQALYGPGDEVLMFEPVFDIYLPQARLAGATPVTVPLRLEGEGSWSLDLDELRAAVTPRTRALLLN
SPHNPTGRIFTREELEALVALARQHDLWLISDEVYDELYFGEPPLSLRTLAPERTFTVGSAGKRLEATGWRVGWVACPPG
FAGNLAGLRQVASFCAPTPFQAAVAAALPIARETGFYGGLREAYVARLDLLAGGLRELGATVFRPSGTYFLMACRPGWEA
ETLVKRAGVAMIPAEAFAANEAPPPGLLRLAFCKSQAELEEALVRLARWEKAGG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=397, Percent_Identity=33.7531486146096, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI169881279, Length=397, Percent_Identity=33.7531486146096, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI56713254, Length=406, Percent_Identity=31.2807881773399, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI56713256, Length=406, Percent_Identity=31.2807881773399, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI169881281, Length=387, Percent_Identity=29.9741602067183, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI4507369, Length=348, Percent_Identity=27.5862068965517, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI7705897, Length=357, Percent_Identity=24.0896358543417, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI33469970, Length=357, Percent_Identity=24.0896358543417, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI19263340, Length=315, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI215599424, Length=287, Percent_Identity=26.4808362369338, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1786816, Length=385, Percent_Identity=34.025974025974, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1788627, Length=256, Percent_Identity=32.03125, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1788722, Length=304, Percent_Identity=28.9473684210526, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787710, Length=241, Percent_Identity=29.8755186721992, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790797, Length=245, Percent_Identity=26.530612244898, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787909, Length=105, Percent_Identity=32.3809523809524, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=336, Percent_Identity=33.3333333333333, Blast_Score=191, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI71994472, Length=419, Percent_Identity=32.4582338902148, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71994476, Length=419, Percent_Identity=32.4582338902148, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=27.2727272727273, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322401, Length=382, Percent_Identity=34.8167539267016, Blast_Score=226, Evalue=4e-60,
Organism=Drosophila melanogaster, GI28573069, Length=414, Percent_Identity=33.5748792270531, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24646114, Length=414, Percent_Identity=33.5748792270531, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI28573067, Length=414, Percent_Identity=33.5748792270531, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI28573065, Length=414, Percent_Identity=33.5748792270531, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI18859735, Length=343, Percent_Identity=25.3644314868805, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356535, Length=336, Percent_Identity=24.1071428571429, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 39964; Mature: 39833

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELLPRARSSQESIFARMSRLAAQYGAINLGQGFPSDAPPAFLLEAARRAVGTADQYAP
CCCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHCCCHHCCC
PAGLPALRDALGADLGVDGADLVVTTGATEALGLLAQALYGPGDEVLMFEPVFDIYLPQA
CCCCHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEECCHHHHHCCCH
RLAGATPVTVPLRLEGEGSWSLDLDELRAAVTPRTRALLLNSPHNPTGRIFTREELEALV
HHCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCEEEHHHHHHHH
ALARQHDLWLISDEVYDELYFGEPPLSLRTLAPERTFTVGSAGKRLEATGWRVGWVACPP
HHHHHCCEEEECHHHHHHHHCCCCCCCEEECCCCCEEEECCCCCEEECCCEEEEEEECCC
GFAGNLAGLRQVASFCAPTPFQAAVAAALPIARETGFYGGLREAYVARLDLLAGGLRELG
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
ATVFRPSGTYFLMACRPGWEAETLVKRAGVAMIPAEAFAANEAPPPGLLRLAFCKSQAEL
CEEECCCCCEEEEEECCCCCHHHHHHHCCCEEECHHHHHCCCCCCCCHHHHHHHHCHHHH
EEALVRLARWEKAGG
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
PELLPRARSSQESIFARMSRLAAQYGAINLGQGFPSDAPPAFLLEAARRAVGTADQYAP
CCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHCCCHHCCC
PAGLPALRDALGADLGVDGADLVVTTGATEALGLLAQALYGPGDEVLMFEPVFDIYLPQA
CCCCHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEECCHHHHHCCCH
RLAGATPVTVPLRLEGEGSWSLDLDELRAAVTPRTRALLLNSPHNPTGRIFTREELEALV
HHCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCEEEHHHHHHHH
ALARQHDLWLISDEVYDELYFGEPPLSLRTLAPERTFTVGSAGKRLEATGWRVGWVACPP
HHHHHCCEEEECHHHHHHHHCCCCCCCEEECCCCCEEEECCCCCEEECCCEEEEEEECCC
GFAGNLAGLRQVASFCAPTPFQAAVAAALPIARETGFYGGLREAYVARLDLLAGGLRELG
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
ATVFRPSGTYFLMACRPGWEAETLVKRAGVAMIPAEAFAANEAPPPGLLRLAFCKSQAEL
CEEECCCCCEEEEEECCCCCHHHHHHHCCCEEECHHHHHCCCCCCCCHHHHHHHHCHHHH
EEALVRLARWEKAGG
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9367851 [H]