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The map label for this gene is msrB [H]

Identifier: 94986171

GI number: 94986171

Start: 2180959

End: 2181417

Strand: Reverse

Name: msrB [H]

Synonym: Dgeo_2072

Alternate gene names: 94986171

Gene position: 2181417-2180959 (Counterclockwise)

Preceding gene: 94986173

Following gene: 94986168

Centisome position: 88.42

GC content: 64.05

Gene sequence:

>459_bases
ATGACTCGTGACTTTGTCAAGCCCAGCGAGGCCGAACTGCGCCAGAAGCTCACGCCTGAGCAGTACCGCGTGACCCAGCA
GGAGGGCACCGAACGCGCCTTTACCGGTGAGTACTGGGACCACGATGAACCCGGCATCTACGTGGATGTGGTATCCGGCG
AACCCCTGTTCAGCTCGCTGGATAAGTACGACGCGGGCTGTGGCTGGCCGTCCTTCACCCGACCCATTCCAGGCGTCACC
CTCACCGAACGGACCGATCACAAGATCGGGTATCCCCGCACCGAGGTCCGTTCCGGCCTGGCCGACTCGCACCTCGGCCA
CGTGTTTCCCGACGGCCCCAGCGAGGCAGGCGGCCTGCGCTACTGCATCAACTCGGCGGCGCTGCGCTTTGTGCCGCTGG
AGCGCCTGGAAGAGGAAGGCTACGGCGAGTACCGGAAACTGTTTGAACAGCAGGACTGA

Upstream 100 bases:

>100_bases
TTTGTTTAGCTTTGTTTTTTAAAGCAACGAGAAGAGCACATTTGCCGGGGAGGCGGGCGAACTCCTATTCCGCTGCCGGG
TCCCCGCCTACACTCGCTGT

Downstream 100 bases:

>100_bases
AGGGAGGGACCACGCCGGTGGTGGCATGTGATCCCACCCCTCGGCAGATCAGCAATCCGGCGTGTGCTGGTCATTAGAAA
TCGGGAGAGGGGCCGCCTCC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MTRDFVKPSEAELRQKLTPEQYRVTQQEGTERAFTGEYWDHDEPGIYVDVVSGEPLFSSLDKYDAGCGWPSFTRPIPGVT
LTERTDHKIGYPRTEVRSGLADSHLGHVFPDGPSEAGGLRYCINSAALRFVPLERLEEEGYGEYRKLFEQQD

Sequences:

>Translated_152_residues
MTRDFVKPSEAELRQKLTPEQYRVTQQEGTERAFTGEYWDHDEPGIYVDVVSGEPLFSSLDKYDAGCGWPSFTRPIPGVT
LTERTDHKIGYPRTEVRSGLADSHLGHVFPDGPSEAGGLRYCINSAALRFVPLERLEEEGYGEYRKLFEQQD
>Mature_151_residues
TRDFVKPSEAELRQKLTPEQYRVTQQEGTERAFTGEYWDHDEPGIYVDVVSGEPLFSSLDKYDAGCGWPSFTRPIPGVTL
TERTDHKIGYPRTEVRSGLADSHLGHVFPDGPSEAGGLRYCINSAALRFVPLERLEEEGYGEYRKLFEQQD

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=126, Percent_Identity=52.3809523809524, Blast_Score=129, Evalue=9e-31,
Organism=Homo sapiens, GI301336162, Length=126, Percent_Identity=52.3809523809524, Blast_Score=129, Evalue=9e-31,
Organism=Homo sapiens, GI73089054, Length=126, Percent_Identity=52.3809523809524, Blast_Score=129, Evalue=9e-31,
Organism=Homo sapiens, GI37620216, Length=126, Percent_Identity=52.3809523809524, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI117606353, Length=131, Percent_Identity=45.0381679389313, Blast_Score=111, Evalue=3e-25,
Organism=Escherichia coli, GI1788077, Length=132, Percent_Identity=47.7272727272727, Blast_Score=124, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17553450, Length=122, Percent_Identity=45.0819672131148, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115532676, Length=122, Percent_Identity=45.0819672131148, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319816, Length=127, Percent_Identity=34.6456692913386, Blast_Score=78, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221378664, Length=127, Percent_Identity=49.6062992125984, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24645799, Length=127, Percent_Identity=49.6062992125984, Blast_Score=119, Evalue=8e-28,
Organism=Drosophila melanogaster, GI45553335, Length=127, Percent_Identity=49.6062992125984, Blast_Score=119, Evalue=9e-28,
Organism=Drosophila melanogaster, GI21356369, Length=127, Percent_Identity=49.6062992125984, Blast_Score=119, Evalue=9e-28,
Organism=Drosophila melanogaster, GI221378662, Length=134, Percent_Identity=47.0149253731343, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24645804, Length=138, Percent_Identity=46.3768115942029, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24645801, Length=138, Percent_Identity=46.3768115942029, Blast_Score=116, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 17275; Mature: 17144

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRDFVKPSEAELRQKLTPEQYRVTQQEGTERAFTGEYWDHDEPGIYVDVVSGEPLFSSL
CCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHH
DKYDAGCGWPSFTRPIPGVTLTERTDHKIGYPRTEVRSGLADSHLGHVFPDGPSEAGGLR
HHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHH
YCINSAALRFVPLERLEEEGYGEYRKLFEQQD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure 
TRDFVKPSEAELRQKLTPEQYRVTQQEGTERAFTGEYWDHDEPGIYVDVVSGEPLFSSL
CCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHH
DKYDAGCGWPSFTRPIPGVTLTERTDHKIGYPRTEVRSGLADSHLGHVFPDGPSEAGGLR
HHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHH
YCINSAALRFVPLERLEEEGYGEYRKLFEQQD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]