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The map label for this gene is appC [H]

Identifier: 94985442

GI number: 94985442

Start: 1428324

End: 1429466

Strand: Reverse

Name: appC [H]

Synonym: Dgeo_1342

Alternate gene names: 94985442

Gene position: 1429466-1428324 (Counterclockwise)

Preceding gene: 94985443

Following gene: 94985441

Centisome position: 57.94

GC content: 62.82

Gene sequence:

>1143_bases
GTGAGCGCCATTTCCTCCAAGGCCCCCGCCCAGTCCCGCAGTACCTCGCAGTCGCAGTGGGCTGTTGTCTGGCGGCAGTT
TCTCAAGCACCCCCTTGCGCGCGTTGGGCTGTTGATCCTCGGCGTGCTGTACCTGCTCGCCATCTTCGCGGGCTTCATCG
CGCCCTACGGCGGCAACCAGTACACCACCGACGCGGCCACCCGCGTCTCATGGGCTCCCCCCACCCCCATTCACATCCGC
AACGCGCAGGGACAGCTCACCCGGCCTTTTATCTACGGCGTCAAGCGAGAGGTGGACTTCACCACCTTCCGGGACAAATA
CGTCGAAGACAAGAGCCAGGTGTATCCCATTCACTTCTTTGTTCGGCGGCCCAGTGCGCGCTACAACCTGTTCGGCCTGA
TTCCGACGGATCTCAAGCTCTTTGGCGTGGACGAGCCGGCCCGGCTCTTTCTCTGGGGCAGCGACAACCTGGGGCGTGAC
CAGTTCAGCCGCATCATGTACGGCGGACAAATCAGCCTCTCGATCGGCTTGATTGCCACTGTTGTTTCGCTGGTGATCGG
ACTCATCTTGGGCGGGATTGCCGGGTATTTCCGAGGCTGGGCCGACACCTTGATTATGCGGACCGTCGAGGTCCTCGTCT
CCATCCCGGACCTGTTCCTGCTGCTCACGCTGCGCGCGCTGCTGCCCATCGACATCAACCCGATCTTTAGCTTTTACCTG
ATCACGGTGATTCTGGCGGCGATCGGCTGGGGCGGGATTGCGCGTGTGGTTCGCAGCCAGCTCCTCAGCACCCGCGAACT
CGATTACGTCCAGGCGGCCACGGCGCTGGGCGCTTCGGACGCCCGCATCATTGGCCAGCACATGCTGCCGGCCACCGCCA
GCTACATCATCGTGATCGCGACCCTCTTGATTCCTGGGTACATCCTGCTGGAAAGCGGTCTGTCGTTCCTGGGGGTCGGT
GTGGTCGAGCCCTATGCCTCATGGGGCAAACTGCTGCAACAGGCCTACGAGGGGGGATTTGAGTCGATCAGCGGACGCCC
TTGGGTGCTGATCCCGGGCCTGTTTATCACGCTGGCCGTGCTGGCCTGGCAGTTTGTGGGGGACGGTCTGCGGGATGCCT
TTGATCCCCGCCGCCGCCGTTAA

Upstream 100 bases:

>100_bases
TGGTGCTGTACGTGATCGGCAACCTGATTTCGGACGTGCTGCTCGCCGCCGTAGATCCCCGCATCCGCTACAGCTGAGGC
TGGAAGAAACGAGGTTGAAC

Downstream 100 bases:

>100_bases
CCGCAGACGGTGGTCCATGTGTCTGTGGGGCGCAGCCTGACCTGTATGATGAAGCGCGTGTCCGACAAAGAGTCGCAGAT
GGAGGAAAAATGACCCACCA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSAISSKAPAQSRSTSQSQWAVVWRQFLKHPLARVGLLILGVLYLLAIFAGFIAPYGGNQYTTDAATRVSWAPPTPIHIR
NAQGQLTRPFIYGVKREVDFTTFRDKYVEDKSQVYPIHFFVRRPSARYNLFGLIPTDLKLFGVDEPARLFLWGSDNLGRD
QFSRIMYGGQISLSIGLIATVVSLVIGLILGGIAGYFRGWADTLIMRTVEVLVSIPDLFLLLTLRALLPIDINPIFSFYL
ITVILAAIGWGGIARVVRSQLLSTRELDYVQAATALGASDARIIGQHMLPATASYIIVIATLLIPGYILLESGLSFLGVG
VVEPYASWGKLLQQAYEGGFESISGRPWVLIPGLFITLAVLAWQFVGDGLRDAFDPRRRR

Sequences:

>Translated_380_residues
MSAISSKAPAQSRSTSQSQWAVVWRQFLKHPLARVGLLILGVLYLLAIFAGFIAPYGGNQYTTDAATRVSWAPPTPIHIR
NAQGQLTRPFIYGVKREVDFTTFRDKYVEDKSQVYPIHFFVRRPSARYNLFGLIPTDLKLFGVDEPARLFLWGSDNLGRD
QFSRIMYGGQISLSIGLIATVVSLVIGLILGGIAGYFRGWADTLIMRTVEVLVSIPDLFLLLTLRALLPIDINPIFSFYL
ITVILAAIGWGGIARVVRSQLLSTRELDYVQAATALGASDARIIGQHMLPATASYIIVIATLLIPGYILLESGLSFLGVG
VVEPYASWGKLLQQAYEGGFESISGRPWVLIPGLFITLAVLAWQFVGDGLRDAFDPRRRR
>Mature_379_residues
SAISSKAPAQSRSTSQSQWAVVWRQFLKHPLARVGLLILGVLYLLAIFAGFIAPYGGNQYTTDAATRVSWAPPTPIHIRN
AQGQLTRPFIYGVKREVDFTTFRDKYVEDKSQVYPIHFFVRRPSARYNLFGLIPTDLKLFGVDEPARLFLWGSDNLGRDQ
FSRIMYGGQISLSIGLIATVVSLVIGLILGGIAGYFRGWADTLIMRTVEVLVSIPDLFLLLTLRALLPIDINPIFSFYLI
TVILAAIGWGGIARVVRSQLLSTRELDYVQAATALGASDARIIGQHMLPATASYIIVIATLLIPGYILLESGLSFLGVGV
VEPYASWGKLLQQAYEGGFESISGRPWVLIPGLFITLAVLAWQFVGDGLRDAFDPRRRR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=280, Percent_Identity=35, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787498, Length=229, Percent_Identity=38.4279475982533, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787760, Length=240, Percent_Identity=33.75, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788505, Length=235, Percent_Identity=35.3191489361702, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1789889, Length=242, Percent_Identity=32.6446280991736, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789964, Length=232, Percent_Identity=36.6379310344828, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787549, Length=225, Percent_Identity=30.2222222222222, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 41980; Mature: 41848

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAISSKAPAQSRSTSQSQWAVVWRQFLKHPLARVGLLILGVLYLLAIFAGFIAPYGGNQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YTTDAATRVSWAPPTPIHIRNAQGQLTRPFIYGVKREVDFTTFRDKYVEDKSQVYPIHFF
EECCHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEE
VRRPSARYNLFGLIPTDLKLFGVDEPARLFLWGSDNLGRDQFSRIMYGGQISLSIGLIAT
EECCCCCEEEEEECCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCEEEEHHHHHHH
VVSLVIGLILGGIAGYFRGWADTLIMRTVEVLVSIPDLFLLLTLRALLPIDINPIFSFYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ITVILAAIGWGGIARVVRSQLLSTRELDYVQAATALGASDARIIGQHMLPATASYIIVIA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
TLLIPGYILLESGLSFLGVGVVEPYASWGKLLQQAYEGGFESISGRPWVLIPGLFITLAV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEECHHHHHHHH
LAWQFVGDGLRDAFDPRRRR
HHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
SAISSKAPAQSRSTSQSQWAVVWRQFLKHPLARVGLLILGVLYLLAIFAGFIAPYGGNQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YTTDAATRVSWAPPTPIHIRNAQGQLTRPFIYGVKREVDFTTFRDKYVEDKSQVYPIHFF
EECCHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEE
VRRPSARYNLFGLIPTDLKLFGVDEPARLFLWGSDNLGRDQFSRIMYGGQISLSIGLIAT
EECCCCCEEEEEECCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCEEEEHHHHHHH
VVSLVIGLILGGIAGYFRGWADTLIMRTVEVLVSIPDLFLLLTLRALLPIDINPIFSFYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ITVILAAIGWGGIARVVRSQLLSTRELDYVQAATALGASDARIIGQHMLPATASYIIVIA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
TLLIPGYILLESGLSFLGVGVVEPYASWGKLLQQAYEGGFESISGRPWVLIPGLFITLAV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEECHHHHHHHH
LAWQFVGDGLRDAFDPRRRR
HHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]