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The map label for this gene is appB [H]

Identifier: 94985443

GI number: 94985443

Start: 1429490

End: 1430470

Strand: Reverse

Name: appB [H]

Synonym: Dgeo_1343

Alternate gene names: 94985443

Gene position: 1430470-1429490 (Counterclockwise)

Preceding gene: 94985444

Following gene: 94985442

Centisome position: 57.98

GC content: 60.86

Gene sequence:

>981_bases
ATGATTCCGTTTCTCCTCCGCCGGTTGTTACAGCTTATCCCGGTGTTTCTGCTGTCCACCGTGTTGGTGTTCTTTATCAT
CCAGGCTGCGCCGGGCGACTTTGCCAGCACGCTGCGCGGCAATCCAGCCATCAAGCCCGAAACTGTCGCGCAGGTGATCC
GGCGCTACCACCTCGACCAACCGGTCTACGTGCAGTACTTTGCCTGGTTGGGTAACTTCCTGCGGGGTGATCTGGGGGTG
GCCTTTACCGAAAACCGGCCCGTTTGGGAGGTGCTCGCGCCGCGGATCGGCAACAGCCTGATTCTGGTGGGCCTCAGTAC
GCTGCTGACGTATCTGATTGCTATTCCAGTCGGTGTTTACGGCGCGGTGCGGCCCTACAGCCTGGGTGACCGCCTGATCT
CCTTTGTGACCTACTTTGGGCTGGGGATTCCGTCCTTCTTTTTCATGATGCTGGTCATGTTCCTGATGGTGACCCTGAAG
CAGAAGTTCGGTTGGGACGTGCCCATCAGCGGCAAGAGCAGTTCGACGCTGGGAGACGTGCCGCAGTGGCGGTACATTCT
GGACGTTCTGATCTATGCGTTGCCGCCCAGCTTTGTCATCGCGCTGCGCTCCATCTCGTCCGAGAGCCGCCTGCTGCGGG
GACAGATGCTGGAGGTGCTCAACCAGGACTACATCCGGACATCGCGGGCCAAGGGCCTGACCCAGAATCGCACCGTGTAC
AAGCATGCCTTCCGCAACGCGGTGCTGCCGCTGGTAGCGGGCTTGGGTGGTCTGCTGACCGGCTTGATTTCGGGGGCGGG
CTTTGTTGAGGTGACCTACGGCTATCCGGGCCTCACGCCGCGCCTGCTGGAAGCGTTGTCCACGCAGGATCTGTACCTGC
TGGTGTCCACCACGTCGTTGACGGTGGTGCTGTACGTGATCGGCAACCTGATTTCGGACGTGCTGCTCGCCGCCGTAGAT
CCCCGCATCCGCTACAGCTGA

Upstream 100 bases:

>100_bases
AGACCTGGATCAAGAAGTAAAGCGGACGGTTTGTAGACCTCCGCACCGCAACGCGAGGCCGCCGGGCCTCGCGTTCGCCC
TGAAGGAGCAAGATAACCCC

Downstream 100 bases:

>100_bases
GGCTGGAAGAAACGAGGTTGAACGTGAGCGCCATTTCCTCCAAGGCCCCCGCCCAGTCCCGCAGTACCTCGCAGTCGCAG
TGGGCTGTTGTCTGGCGGCA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MIPFLLRRLLQLIPVFLLSTVLVFFIIQAAPGDFASTLRGNPAIKPETVAQVIRRYHLDQPVYVQYFAWLGNFLRGDLGV
AFTENRPVWEVLAPRIGNSLILVGLSTLLTYLIAIPVGVYGAVRPYSLGDRLISFVTYFGLGIPSFFFMMLVMFLMVTLK
QKFGWDVPISGKSSSTLGDVPQWRYILDVLIYALPPSFVIALRSISSESRLLRGQMLEVLNQDYIRTSRAKGLTQNRTVY
KHAFRNAVLPLVAGLGGLLTGLISGAGFVEVTYGYPGLTPRLLEALSTQDLYLLVSTTSLTVVLYVIGNLISDVLLAAVD
PRIRYS

Sequences:

>Translated_326_residues
MIPFLLRRLLQLIPVFLLSTVLVFFIIQAAPGDFASTLRGNPAIKPETVAQVIRRYHLDQPVYVQYFAWLGNFLRGDLGV
AFTENRPVWEVLAPRIGNSLILVGLSTLLTYLIAIPVGVYGAVRPYSLGDRLISFVTYFGLGIPSFFFMMLVMFLMVTLK
QKFGWDVPISGKSSSTLGDVPQWRYILDVLIYALPPSFVIALRSISSESRLLRGQMLEVLNQDYIRTSRAKGLTQNRTVY
KHAFRNAVLPLVAGLGGLLTGLISGAGFVEVTYGYPGLTPRLLEALSTQDLYLLVSTTSLTVVLYVIGNLISDVLLAAVD
PRIRYS
>Mature_326_residues
MIPFLLRRLLQLIPVFLLSTVLVFFIIQAAPGDFASTLRGNPAIKPETVAQVIRRYHLDQPVYVQYFAWLGNFLRGDLGV
AFTENRPVWEVLAPRIGNSLILVGLSTLLTYLIAIPVGVYGAVRPYSLGDRLISFVTYFGLGIPSFFFMMLVMFLMVTLK
QKFGWDVPISGKSSSTLGDVPQWRYILDVLIYALPPSFVIALRSISSESRLLRGQMLEVLNQDYIRTSRAKGLTQNRTVY
KHAFRNAVLPLVAGLGGLLTGLISGAGFVEVTYGYPGLTPRLLEALSTQDLYLLVSTTSLTVVLYVIGNLISDVLLAAVD
PRIRYS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=344, Percent_Identity=33.4302325581395, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1789888, Length=327, Percent_Identity=33.0275229357798, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1787497, Length=327, Percent_Identity=31.4984709480122, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787053, Length=331, Percent_Identity=31.7220543806647, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1788504, Length=365, Percent_Identity=27.1232876712329, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787761, Length=301, Percent_Identity=30.2325581395349, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787550, Length=271, Percent_Identity=25.4612546125461, Blast_Score=98, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36171; Mature: 36171

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPFLLRRLLQLIPVFLLSTVLVFFIIQAAPGDFASTLRGNPAIKPETVAQVIRRYHLDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCC
PVYVQYFAWLGNFLRGDLGVAFTENRPVWEVLAPRIGNSLILVGLSTLLTYLIAIPVGVY
CHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GAVRPYSLGDRLISFVTYFGLGIPSFFFMMLVMFLMVTLKQKFGWDVPISGKSSSTLGDV
HCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PQWRYILDVLIYALPPSFVIALRSISSESRLLRGQMLEVLNQDYIRTSRAKGLTQNRTVY
HHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KHAFRNAVLPLVAGLGGLLTGLISGAGFVEVTYGYPGLTPRLLEALSTQDLYLLVSTTSL
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCEEEEEEHHHH
TVVLYVIGNLISDVLLAAVDPRIRYS
HHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIPFLLRRLLQLIPVFLLSTVLVFFIIQAAPGDFASTLRGNPAIKPETVAQVIRRYHLDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCC
PVYVQYFAWLGNFLRGDLGVAFTENRPVWEVLAPRIGNSLILVGLSTLLTYLIAIPVGVY
CHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GAVRPYSLGDRLISFVTYFGLGIPSFFFMMLVMFLMVTLKQKFGWDVPISGKSSSTLGDV
HCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PQWRYILDVLIYALPPSFVIALRSISSESRLLRGQMLEVLNQDYIRTSRAKGLTQNRTVY
HHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KHAFRNAVLPLVAGLGGLLTGLISGAGFVEVTYGYPGLTPRLLEALSTQDLYLLVSTTSL
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCEEEEEEHHHH
TVVLYVIGNLISDVLLAAVDPRIRYS
HHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]