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The map label for this gene is 94985425

Identifier: 94985425

GI number: 94985425

Start: 1407608

End: 1408543

Strand: Reverse

Name: 94985425

Synonym: Dgeo_1324

Alternate gene names: NA

Gene position: 1408543-1407608 (Counterclockwise)

Preceding gene: 94985426

Following gene: 94985424

Centisome position: 57.09

GC content: 72.01

Gene sequence:

>936_bases
ATGAGCGCGCCGCCTGCACCCGCCGCTGTCTTCGTGGGCCGCTTTCAGCCGCCACACGCGGCGCACGTGGCGACGGTGCA
GCACGCGCTGGTCCACGCCTCCCGGGTACTGGTGCTGCTGGGAAGCGCCAATCTCGCCCGCAGCATCCGCAATCCCTTCA
GCGCCCCCGAACGTGCGGCGATGTTCGGAGCCGCTCTGCGCGAAACCGGGGTGCGGCGGGGCCGTGTCCTCTTCCGCCCG
CTCCCCGACCGCTTCAATGCCGAGCTGTGGGCGGCGGACGTGCGCGCTGCGGCAGCGGAGGTCTTCGGCCCGGAGACGCC
CGTTCAGCTCGTCGGCTTTGAAAAGGATGCGAGCACCGCCTACCTGCGCTGGTTTCCTGCCTGGGAACGCCTGCCCGCGC
CCGAACTGCCGGGCTTGAATGCGACCGACCTGCGCGCGGCCTGGCTGACCGGGCGGCCCCTGCCGGAGGGCGTACCGCCA
CCCGTGCGTGCCTTTTTGGCCCGCTTTGCGGTGACCCCCGCCTTTATCCGCCTGCAAGCGGAATGGGCGGCGGTGGAGGC
GGCCCGTGCGGTCCTTCCGCCCGGCGTTCACCTGCACGAGGAACGCTGGTTACACGTCGCGCAGGGGCAGGTCTGGCTGC
ACACGCGCCAGGATGACATCGGGCGCGGGCTGTGGGAGCTGCCGGGCCGTGTTCTTCCGCCCGGTGAGCTGCCCGCCACC
CCCGCCGACGCGCTGTTTGACCACCCTGCCCGCGCCCTGGTCGCGCCCACCGCCGCGCACGTGTGGTTGGGTCCGCCGCC
CGCCTCCTTTGTCGCCCGGCCTGTCTCCCTGCAGCGCGCCCTGGCCCTGCCGCGCCGTTTCTTTGAAGACCATCACGTCA
TCCTGACGCGGCTGTGGGTTCGGGAGTCAGCGGGCAGGTCGGTCCCTCCAGCCTGA

Upstream 100 bases:

>100_bases
GCCGTCCCCTCAATCCCCATATCTACCGCGTCAGCCTGGGAGATGACGTGGCCGGATTGCGCGACCGTGTGGCAGAGGAG
CTGCGTGCGCACGTGGGGAG

Downstream 100 bases:

>100_bases
GGCATTGGGCCAAGGGTTGCTCTCTGCCATATTATGTTTTAAACTAAAAAAATAGAGGAATTTCGAGAAAGCCCGTTCCC
GGTATGAGGCTTCCCGCCCC

Product: bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase

Products: NA

Alternate protein names: Nicotinamide-nucleotide adenylyltransferase; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; NMN adenylyltransferase; ADP compounds hydrolase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSAPPAPAAVFVGRFQPPHAAHVATVQHALVHASRVLVLLGSANLARSIRNPFSAPERAAMFGAALRETGVRRGRVLFRP
LPDRFNAELWAADVRAAAAEVFGPETPVQLVGFEKDASTAYLRWFPAWERLPAPELPGLNATDLRAAWLTGRPLPEGVPP
PVRAFLARFAVTPAFIRLQAEWAAVEAARAVLPPGVHLHEERWLHVAQGQVWLHTRQDDIGRGLWELPGRVLPPGELPAT
PADALFDHPARALVAPTAAHVWLGPPPASFVARPVSLQRALALPRRFFEDHHVILTRLWVRESAGRSVPPA

Sequences:

>Translated_311_residues
MSAPPAPAAVFVGRFQPPHAAHVATVQHALVHASRVLVLLGSANLARSIRNPFSAPERAAMFGAALRETGVRRGRVLFRP
LPDRFNAELWAADVRAAAAEVFGPETPVQLVGFEKDASTAYLRWFPAWERLPAPELPGLNATDLRAAWLTGRPLPEGVPP
PVRAFLARFAVTPAFIRLQAEWAAVEAARAVLPPGVHLHEERWLHVAQGQVWLHTRQDDIGRGLWELPGRVLPPGELPAT
PADALFDHPARALVAPTAAHVWLGPPPASFVARPVSLQRALALPRRFFEDHHVILTRLWVRESAGRSVPPA
>Mature_310_residues
SAPPAPAAVFVGRFQPPHAAHVATVQHALVHASRVLVLLGSANLARSIRNPFSAPERAAMFGAALRETGVRRGRVLFRPL
PDRFNAELWAADVRAAAAEVFGPETPVQLVGFEKDASTAYLRWFPAWERLPAPELPGLNATDLRAAWLTGRPLPEGVPPP
VRAFLARFAVTPAFIRLQAEWAAVEAARAVLPPGVHLHEERWLHVAQGQVWLHTRQDDIGRGLWELPGRVLPPGELPATP
ADALFDHPARALVAPTAAHVWLGPPPASFVARPVSLQRALALPRRFFEDHHVILTRLWVRESAGRSVPPA

Specific function: The Nudix hydrolase domain is active on ADP-ribose, (2')-phospho-ADP-ribose, IDP-ribose and NADPH [H]

COG id: COG1056

COG function: function code H; Nicotinamide mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00293 NUDIX [H]

EC number: =2.7.7.1 [H]

Molecular weight: Translated: 33945; Mature: 33814

Theoretical pI: Translated: 11.67; Mature: 11.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPPAPAAVFVGRFQPPHAAHVATVQHALVHASRVLVLLGSANLARSIRNPFSAPERAA
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCCHHHHH
MFGAALRETGVRRGRVLFRPLPDRFNAELWAADVRAAAAEVFGPETPVQLVGFEKDASTA
HHHHHHHHCCCCCCCEEEECCCCHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCE
YLRWFPAWERLPAPELPGLNATDLRAAWLTGRPLPEGVPPPVRAFLARFAVTPAFIRLQA
EEEEECCHHCCCCCCCCCCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHEEEEH
EWAAVEAARAVLPPGVHLHEERWLHVAQGQVWLHTRQDDIGRGLWELPGRVLPPGELPAT
HHHHHHHHHHHCCCCCEECHHHEEEEECCEEEEEECCCHHHCCHHHCCCCCCCCCCCCCC
PADALFDHPARALVAPTAAHVWLGPPPASFVARPVSLQRALALPRRFFEDHHVILTRLWV
CHHHHHCCCCHHHCCCCCCEEEECCCCHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHH
RESAGRSVPPA
HHCCCCCCCCC
>Mature Secondary Structure 
SAPPAPAAVFVGRFQPPHAAHVATVQHALVHASRVLVLLGSANLARSIRNPFSAPERAA
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCCHHHHH
MFGAALRETGVRRGRVLFRPLPDRFNAELWAADVRAAAAEVFGPETPVQLVGFEKDASTA
HHHHHHHHCCCCCCCEEEECCCCHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCE
YLRWFPAWERLPAPELPGLNATDLRAAWLTGRPLPEGVPPPVRAFLARFAVTPAFIRLQA
EEEEECCHHCCCCCCCCCCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHEEEEH
EWAAVEAARAVLPPGVHLHEERWLHVAQGQVWLHTRQDDIGRGLWELPGRVLPPGELPAT
HHHHHHHHHHHCCCCCEECHHHEEEEECCEEEEEECCCHHHCCHHHCCCCCCCCCCCCCC
PADALFDHPARALVAPTAAHVWLGPPPASFVARPVSLQRALALPRRFFEDHHVILTRLWV
CHHHHHCCCCHHHCCCCCCEEEECCCCHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHH
RESAGRSVPPA
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10050763 [H]