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The map label for this gene is recQ [H]

Identifier: 94985328

GI number: 94985328

Start: 1306355

End: 1306942

Strand: Reverse

Name: recQ [H]

Synonym: Dgeo_1226

Alternate gene names: 94985328

Gene position: 1306942-1306355 (Counterclockwise)

Preceding gene: 94985329

Following gene: 94985327

Centisome position: 52.97

GC content: 68.71

Gene sequence:

>588_bases
ATGGTGTACGGCCTGTCGCGCCGATCGGTGGAGGAGACAGCGAGCTGGCTTCAGGCGCAGGGGGTGGACGCGCTGCCCTA
CCATGCGGGCCTCGCGCCGCGTGAGCGCAACCTGGCGCAGGACCGCTTTCTGAGCGAGGAAGGGCTGATCGTGGTGGCGA
CGGTGGCGTTCGGTATAGGCATCGATAAGCCCAATGTGCGCTTCGTGGCGCACCTCGCCCTCCCCAAGAGCCTGGAGGGC
TACTCCCAGGAGACGCCCAAAGCCCGTGCCCTCCTGCGGGAGGACACCTTCGCTCCCAAACCCGCCCGGCGGGAACGCGC
CCGCGCTCCCCGCAAGGGAGGCGCCCTGGTGGACCATCAGGACCGCCCCCTCTTCGAGGCCCTGCGCCAGTGGCGGCTCG
CGAAGGCGCGTGAGCAGGCGGTCCCGCCCTACGTGATCTTTAACGACGCGACCCTGAAGATCATCGCGGAGCTGCGTCCC
GGCAGCCTGCCCACGCTGGACACCGTCAGTGGCGTTGAGACACACAAACTGGAGCAGTATGGCGAGGACGTGCTGGCGGT
GGTCCGGACGCACTCCGGGAGACGGTGA

Upstream 100 bases:

>100_bases
CTTCGACCGCCCCAACATTCAGTACCGCGTGACGCAGAAGACGGGCCCCAAGACCTAGCTCCTCGACTTCATCCGCGCCG
AACACCCGGGCGAGGCAGGC

Downstream 100 bases:

>100_bases
CAGGCCCCCTGCCTAGGACGGACGGCGCAGGCAGGGGAGAGCAAGAGGGGAACTTGACGGCCGCGAGAGTTGTAATTACT
CTGATTACAGGTTGGTGACG

Product: HRDC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MVYGLSRRSVEETASWLQAQGVDALPYHAGLAPRERNLAQDRFLSEEGLIVVATVAFGIGIDKPNVRFVAHLALPKSLEG
YSQETPKARALLREDTFAPKPARRERARAPRKGGALVDHQDRPLFEALRQWRLAKAREQAVPPYVIFNDATLKIIAELRP
GSLPTLDTVSGVETHKLEQYGEDVLAVVRTHSGRR

Sequences:

>Translated_195_residues
MVYGLSRRSVEETASWLQAQGVDALPYHAGLAPRERNLAQDRFLSEEGLIVVATVAFGIGIDKPNVRFVAHLALPKSLEG
YSQETPKARALLREDTFAPKPARRERARAPRKGGALVDHQDRPLFEALRQWRLAKAREQAVPPYVIFNDATLKIIAELRP
GSLPTLDTVSGVETHKLEQYGEDVLAVVRTHSGRR
>Mature_195_residues
MVYGLSRRSVEETASWLQAQGVDALPYHAGLAPRERNLAQDRFLSEEGLIVVATVAFGIGIDKPNVRFVAHLALPKSLEG
YSQETPKARALLREDTFAPKPARRERARAPRKGGALVDHQDRPLFEALRQWRLAKAREQAVPPYVIFNDATLKIIAELRP
GSLPTLDTVSGVETHKLEQYGEDVLAVVRTHSGRR

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=89, Percent_Identity=49.438202247191, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI51242947, Length=88, Percent_Identity=46.5909090909091, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI51242943, Length=88, Percent_Identity=46.5909090909091, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI148612816, Length=88, Percent_Identity=46.5909090909091, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI14591902, Length=88, Percent_Identity=43.1818181818182, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI14591904, Length=88, Percent_Identity=43.1818181818182, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI284005309, Length=80, Percent_Identity=45, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI48994977, Length=88, Percent_Identity=51.1363636363636, Blast_Score=95, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71987993, Length=88, Percent_Identity=48.8636363636364, Blast_Score=90, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71987997, Length=88, Percent_Identity=48.8636363636364, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25145561, Length=88, Percent_Identity=47.7272727272727, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17552866, Length=140, Percent_Identity=35.7142857142857, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI32564293, Length=88, Percent_Identity=39.7727272727273, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323844, Length=88, Percent_Identity=46.5909090909091, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646066, Length=88, Percent_Identity=48.8636363636364, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24664230, Length=88, Percent_Identity=40.9090909090909, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI62472181, Length=88, Percent_Identity=40.9090909090909, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664226, Length=88, Percent_Identity=40.9090909090909, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358123, Length=65, Percent_Identity=49.2307692307692, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21710; Mature: 21710

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYGLSRRSVEETASWLQAQGVDALPYHAGLAPRERNLAQDRFLSEEGLIVVATVAFGIG
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHCC
IDKPNVRFVAHLALPKSLEGYSQETPKARALLREDTFAPKPARRERARAPRKGGALVDHQ
CCCCCCEEEEEECCCCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCC
DRPLFEALRQWRLAKAREQAVPPYVIFNDATLKIIAELRPGSLPTLDTVSGVETHKLEQY
CCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
GEDVLAVVRTHSGRR
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MVYGLSRRSVEETASWLQAQGVDALPYHAGLAPRERNLAQDRFLSEEGLIVVATVAFGIG
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHCC
IDKPNVRFVAHLALPKSLEGYSQETPKARALLREDTFAPKPARRERARAPRKGGALVDHQ
CCCCCCEEEEEECCCCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCC
DRPLFEALRQWRLAKAREQAVPPYVIFNDATLKIIAELRPGSLPTLDTVSGVETHKLEQY
CCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
GEDVLAVVRTHSGRR
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]