| Definition | Deinococcus geothermalis DSM 11300, complete genome. |
|---|---|
| Accession | NC_008025 |
| Length | 2,467,205 |
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The map label for this gene is pbpA [H]
Identifier: 94985172
GI number: 94985172
Start: 1138373
End: 1140721
Strand: Reverse
Name: pbpA [H]
Synonym: Dgeo_1068
Alternate gene names: 94985172
Gene position: 1140721-1138373 (Counterclockwise)
Preceding gene: 94985173
Following gene: 94985171
Centisome position: 46.24
GC content: 64.88
Gene sequence:
>2349_bases TTGTTTCTGAGGTTTCTGAAATTCACCACGTCGCTGCTGCTGGCGGGGGGCGTGGCCGCCGCTGGGGTGGGAGCCACGTA CGTCACCAAATGGACACGTGAGCTGCCCGACTACCGCGAACTCGATAACCTGAGCCTGGGCGCCGAGACGCGGGTCTTCG CGCGCGACGGCACACCGCTAGGCACCCTGGTGCCCAGGATCGGGGATCAAGCGATCAGCCGCACACTGGTACGCCTGGAC GAGATTAGCCCCTTTATGACGGCGGCGCTGATCTCCAACGAGGACCGTCACTTCTTTGAGCACTACGGCCTAGATCCCTA CGGCATCGCCCGGCAGTTCCGCCGGGTGGCGCAGGGCGAGGACGTGCAGGGGGGATCGACCCTCACCAACCAGCTCGTCA AAAACACACTGCTCCTCAAAGAGTACAACCAGGCCAGGACGCCCGACCGCAAAGTCAAGGAATGGCTGCTCTCGGTGCAG GTCGAGCGTGCCTTTACCAAGGAAGAAATCCTGCGCGACTATCTCAACGCGATCTACTGGGGGGACGGCGGGCCGGTGGA ACTGTACGGCATCTACTCGGCGGCGCAGGCCTACTTCCGCAAGACGCCCAAACAGCTCTCGCTGGCCGAAAGTGTCTACC TGACGGTGCTGGTGCCCAATCCCAGCCGCTACTTCAACTACCCGGCGATGCGGCCCCTGATGAAAGTCCTCCTCAAGCGC ATGGTGGAAGATGGCTGGGTGACGCAAGCCCAGGCTGACGCCGCGTGGCACGAGAAGCTGCAGCCGCGCGGCTGGCAGGT CAAGTACGACGCACAGGGGAACGTGGTGAGCGCCAAGCTGGTCGACCGCTCGGCCAAGGAACTCAAGGCGGTGACCACCA CCCGCGCCCCGCACTTTATGGGTCAGGTCGAACAGGAGCTGGTCCGCCGCTTCGGGCGCGACAAGGTGTATGGCTCGGGC GGCCTGCGGGTGTACACCACGCTCGACCCCAAGATTCAAAACGCGGTGGAGACGGCCAGCCGTGAGGCGCGGGGCCTGCC GCCGGGCGCTACGCTGGGTGCGGTTGTGATCGACCCCTACACCGCAGAAGTGCTGGGCATGATCGGGCAAAAGATCGTGC CAGGACAGCCGCTGCCCGATTGGAACAACGCCGCGCAGGGTCAGCGACAGGTGGGCTCGACCATCAAGCCGCTGCTGTAC ACCACCGCGCTCTCGACCGGCCTCGATCAGGCCCACCGCGAGGACGATAAGCCGATTGCCTTTCCCTGCGATACCTGCAA GGGAGGTGTCTACAAGCCGCAGAACTTCGAGGGCCACACCACCTACCGCAGCATGACCATCCGCGAGGCGCTGGACCGCT CGCTCAACCTGGTGACTGTGCGACTGGCGGACCGAATCGGCCTCCAGACCTTTTTCACCAAGCTGCGCGAGCTGGGCATT CCGCCGAACGACGGAACCGGCTTGGCAGCGGCGCTGGGGGCAATCGAGACGACGCCGGTCAAGATGGCAGCAGCCTATGC CCCCTTTGTGAATGGCGGCCTATACCGCGCGCCCCGCTACATCACTCGGGTGACGAATGCGCGCGGCGAGGTGCTGTACG ACGCGGCCAATGACCTTACCCAAGCCAAGCGTGTCTGGACGCCGCAGGTTGCCTTCCTGGGCCTGGATATGATTCGGGGG GTGGTCAACGACCTCACGGCCCGTCAGGGGGGATTGGCCTGGCCCGCCAAGTTCGGTCAATGGCCGGTGGCGGGCAAGAC CGGCACGAGTAACGGCCCCAAGGACTTCTGGTTCGTGGGCACCACGCCCCTCTATACCGGCGCGGTGTGGGTCGGCAAGC AGCAGGGCGGCGAAATGCCCACCAACTACTACAGCGGCTTGGTGAACGCCCCGATCTGGCGGCGAATGATGGAGATCGCG CACGCCGGAAAGACGCCCACCCAGTTCGTGCAGCCTCCCGGCATTGTGTACGCCGACGCGCCCGATCAGAACTGGTTGCC CGGTGTGAAGATCGCCATGCTTGATCCCCGTTACCAAGACAGCTCCAAGACACCGCTGGAGACGGACAGCGCAGCCCAGC CGGTCTATCAGGAAACGACCTGGACACCCGGCCCGGCGGATCCCCGCACTCAGCTGGTCAGCCTAGACCGCACCACTGGC CGCTTGGCGACCGAGTTCACACCGCCAGAAAACATCGTCCAGCGCCGCATCGCCATCGAGGATCTGCCTGCCTATGCGCC CGATCCCAACCCGCAACCCCTGCTCGACCAGCAGCCGGATCCCCAGGCGCTCAAGGCAATCCGTACCCCCAGCACCGCCC CCGCACCAAACACCCAGAGTGCGCCCTGA
Upstream 100 bases:
>100_bases CCGCTGAGCGGCAAGAACCTGCGCGGGCGCATCAACCAGCTGATCGAGGCGCGGCGCCGGTGAAGCCGGAGCAAGGCCGC ACCACAAAGGAGAACACCGC
Downstream 100 bases:
>100_bases CGCCTCACTCTTCCGCAGCCCCCGCCAGGAGCGGCGGGGGTTCTTTGGGTGGACTCAGGACGTTGGGAGGCGGACGCGGA CCTTCTCACGCGGCTGTCAC
Product: peptidoglycan glycosyltransferase
Products: NA
Alternate protein names: PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 782; Mature: 782
Protein sequence:
>782_residues MFLRFLKFTTSLLLAGGVAAAGVGATYVTKWTRELPDYRELDNLSLGAETRVFARDGTPLGTLVPRIGDQAISRTLVRLD EISPFMTAALISNEDRHFFEHYGLDPYGIARQFRRVAQGEDVQGGSTLTNQLVKNTLLLKEYNQARTPDRKVKEWLLSVQ VERAFTKEEILRDYLNAIYWGDGGPVELYGIYSAAQAYFRKTPKQLSLAESVYLTVLVPNPSRYFNYPAMRPLMKVLLKR MVEDGWVTQAQADAAWHEKLQPRGWQVKYDAQGNVVSAKLVDRSAKELKAVTTTRAPHFMGQVEQELVRRFGRDKVYGSG GLRVYTTLDPKIQNAVETASREARGLPPGATLGAVVIDPYTAEVLGMIGQKIVPGQPLPDWNNAAQGQRQVGSTIKPLLY TTALSTGLDQAHREDDKPIAFPCDTCKGGVYKPQNFEGHTTYRSMTIREALDRSLNLVTVRLADRIGLQTFFTKLRELGI PPNDGTGLAAALGAIETTPVKMAAAYAPFVNGGLYRAPRYITRVTNARGEVLYDAANDLTQAKRVWTPQVAFLGLDMIRG VVNDLTARQGGLAWPAKFGQWPVAGKTGTSNGPKDFWFVGTTPLYTGAVWVGKQQGGEMPTNYYSGLVNAPIWRRMMEIA HAGKTPTQFVQPPGIVYADAPDQNWLPGVKIAMLDPRYQDSSKTPLETDSAAQPVYQETTWTPGPADPRTQLVSLDRTTG RLATEFTPPENIVQRRIAIEDLPAYAPDPNPQPLLDQQPDPQALKAIRTPSTAPAPNTQSAP
Sequences:
>Translated_782_residues MFLRFLKFTTSLLLAGGVAAAGVGATYVTKWTRELPDYRELDNLSLGAETRVFARDGTPLGTLVPRIGDQAISRTLVRLD EISPFMTAALISNEDRHFFEHYGLDPYGIARQFRRVAQGEDVQGGSTLTNQLVKNTLLLKEYNQARTPDRKVKEWLLSVQ VERAFTKEEILRDYLNAIYWGDGGPVELYGIYSAAQAYFRKTPKQLSLAESVYLTVLVPNPSRYFNYPAMRPLMKVLLKR MVEDGWVTQAQADAAWHEKLQPRGWQVKYDAQGNVVSAKLVDRSAKELKAVTTTRAPHFMGQVEQELVRRFGRDKVYGSG GLRVYTTLDPKIQNAVETASREARGLPPGATLGAVVIDPYTAEVLGMIGQKIVPGQPLPDWNNAAQGQRQVGSTIKPLLY TTALSTGLDQAHREDDKPIAFPCDTCKGGVYKPQNFEGHTTYRSMTIREALDRSLNLVTVRLADRIGLQTFFTKLRELGI PPNDGTGLAAALGAIETTPVKMAAAYAPFVNGGLYRAPRYITRVTNARGEVLYDAANDLTQAKRVWTPQVAFLGLDMIRG VVNDLTARQGGLAWPAKFGQWPVAGKTGTSNGPKDFWFVGTTPLYTGAVWVGKQQGGEMPTNYYSGLVNAPIWRRMMEIA HAGKTPTQFVQPPGIVYADAPDQNWLPGVKIAMLDPRYQDSSKTPLETDSAAQPVYQETTWTPGPADPRTQLVSLDRTTG RLATEFTPPENIVQRRIAIEDLPAYAPDPNPQPLLDQQPDPQALKAIRTPSTAPAPNTQSAP >Mature_782_residues MFLRFLKFTTSLLLAGGVAAAGVGATYVTKWTRELPDYRELDNLSLGAETRVFARDGTPLGTLVPRIGDQAISRTLVRLD EISPFMTAALISNEDRHFFEHYGLDPYGIARQFRRVAQGEDVQGGSTLTNQLVKNTLLLKEYNQARTPDRKVKEWLLSVQ VERAFTKEEILRDYLNAIYWGDGGPVELYGIYSAAQAYFRKTPKQLSLAESVYLTVLVPNPSRYFNYPAMRPLMKVLLKR MVEDGWVTQAQADAAWHEKLQPRGWQVKYDAQGNVVSAKLVDRSAKELKAVTTTRAPHFMGQVEQELVRRFGRDKVYGSG GLRVYTTLDPKIQNAVETASREARGLPPGATLGAVVIDPYTAEVLGMIGQKIVPGQPLPDWNNAAQGQRQVGSTIKPLLY TTALSTGLDQAHREDDKPIAFPCDTCKGGVYKPQNFEGHTTYRSMTIREALDRSLNLVTVRLADRIGLQTFFTKLRELGI PPNDGTGLAAALGAIETTPVKMAAAYAPFVNGGLYRAPRYITRVTNARGEVLYDAANDLTQAKRVWTPQVAFLGLDMIRG VVNDLTARQGGLAWPAKFGQWPVAGKTGTSNGPKDFWFVGTTPLYTGAVWVGKQQGGEMPTNYYSGLVNAPIWRRMMEIA HAGKTPTQFVQPPGIVYADAPDQNWLPGVKIAMLDPRYQDSSKTPLETDSAAQPVYQETTWTPGPADPRTQLVSLDRTTG RLATEFTPPENIVQRRIAIEDLPAYAPDPNPQPLLDQQPDPQALKAIRTPSTAPAPNTQSAP
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG0744
COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)
Gene ontology:
Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786343, Length=588, Percent_Identity=31.8027210884354, Blast_Score=198, Evalue=1e-51, Organism=Escherichia coli, GI1788867, Length=573, Percent_Identity=30.1919720767888, Blast_Score=155, Evalue=8e-39, Organism=Escherichia coli, GI87082258, Length=346, Percent_Identity=33.5260115606936, Blast_Score=150, Evalue=3e-37, Organism=Escherichia coli, GI1789601, Length=149, Percent_Identity=35.5704697986577, Blast_Score=89, Evalue=9e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.1.129; 3.4.-.- [C]
Molecular weight: Translated: 86307; Mature: 86307
Theoretical pI: Translated: 9.46; Mature: 9.46
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFLRFLKFTTSLLLAGGVAAAGVGATYVTKWTRELPDYRELDNLSLGAETRVFARDGTPL CHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHCCCHHHHCCCCCCCCCEEEECCCCCH GTLVPRIGDQAISRTLVRLDEISPFMTAALISNEDRHFFEHYGLDPYGIARQFRRVAQGE HHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHCCC DVQGGSTLTNQLVKNTLLLKEYNQARTPDRKVKEWLLSVQVERAFTKEEILRDYLNAIYW CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE GDGGPVELYGIYSAAQAYFRKTPKQLSLAESVYLTVLVPNPSRYFNYPAMRPLMKVLLKR CCCCCEEEEEHHHHHHHHHHCCCHHHHHHCEEEEEEEECCCHHHCCCHHHHHHHHHHHHH MVEDGWVTQAQADAAWHEKLQPRGWQVKYDAQGNVVSAKLVDRSAKELKAVTTTRAPHFM HHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCHHHH GQVEQELVRRFGRDKVYGSGGLRVYTTLDPKIQNAVETASREARGLPPGATLGAVVIDPY HHHHHHHHHHHCCCCEECCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCH TAEVLGMIGQKIVPGQPLPDWNNAAQGQRQVGSTIKPLLYTTALSTGLDQAHREDDKPIA HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE FPCDTCKGGVYKPQNFEGHTTYRSMTIREALDRSLNLVTVRLADRIGLQTFFTKLRELGI ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCC PPNDGTGLAAALGAIETTPVKMAAAYAPFVNGGLYRAPRYITRVTNARGEVLYDAANDLT CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCCHHHHHHHCCCCCEEEHHHHHHH QAKRVWTPQVAFLGLDMIRGVVNDLTARQGGLAWPAKFGQWPVAGKTGTSNGPKDFWFVG HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEEEE TTPLYTGAVWVGKQQGGEMPTNYYSGLVNAPIWRRMMEIAHAGKTPTQFVQPPGIVYADA CCCHHCCEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCHHHCCCCCEEEECC PDQNWLPGVKIAMLDPRYQDSSKTPLETDSAAQPVYQETTWTPGPADPRTQLVSLDRTTG CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHEEEECCCCC RLATEFTPPENIVQRRIAIEDLPAYAPDPNPQPLLDQQPDPQALKAIRTPSTAPAPNTQS CEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC AP CC >Mature Secondary Structure MFLRFLKFTTSLLLAGGVAAAGVGATYVTKWTRELPDYRELDNLSLGAETRVFARDGTPL CHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHCCCHHHHCCCCCCCCCEEEECCCCCH GTLVPRIGDQAISRTLVRLDEISPFMTAALISNEDRHFFEHYGLDPYGIARQFRRVAQGE HHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHCCC DVQGGSTLTNQLVKNTLLLKEYNQARTPDRKVKEWLLSVQVERAFTKEEILRDYLNAIYW CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE GDGGPVELYGIYSAAQAYFRKTPKQLSLAESVYLTVLVPNPSRYFNYPAMRPLMKVLLKR CCCCCEEEEEHHHHHHHHHHCCCHHHHHHCEEEEEEEECCCHHHCCCHHHHHHHHHHHHH MVEDGWVTQAQADAAWHEKLQPRGWQVKYDAQGNVVSAKLVDRSAKELKAVTTTRAPHFM HHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCHHHH GQVEQELVRRFGRDKVYGSGGLRVYTTLDPKIQNAVETASREARGLPPGATLGAVVIDPY HHHHHHHHHHHCCCCEECCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCH TAEVLGMIGQKIVPGQPLPDWNNAAQGQRQVGSTIKPLLYTTALSTGLDQAHREDDKPIA HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE FPCDTCKGGVYKPQNFEGHTTYRSMTIREALDRSLNLVTVRLADRIGLQTFFTKLRELGI ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCC PPNDGTGLAAALGAIETTPVKMAAAYAPFVNGGLYRAPRYITRVTNARGEVLYDAANDLT CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCCHHHHHHHCCCCCEEEHHHHHHH QAKRVWTPQVAFLGLDMIRGVVNDLTARQGGLAWPAKFGQWPVAGKTGTSNGPKDFWFVG HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEEEE TTPLYTGAVWVGKQQGGEMPTNYYSGLVNAPIWRRMMEIAHAGKTPTQFVQPPGIVYADA CCCHHCCEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCHHHCCCCCEEEECC PDQNWLPGVKIAMLDPRYQDSSKTPLETDSAAQPVYQETTWTPGPADPRTQLVSLDRTTG CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHEEEECCCCC RLATEFTPPENIVQRRIAIEDLPAYAPDPNPQPLLDQQPDPQALKAIRTPSTAPAPNTQS CEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC AP CC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA