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The map label for this gene is tsf

Identifier: 94985152

GI number: 94985152

Start: 1119792

End: 1120601

Strand: Reverse

Name: tsf

Synonym: Dgeo_1048

Alternate gene names: 94985152

Gene position: 1120601-1119792 (Counterclockwise)

Preceding gene: 94985153

Following gene: 94985151

Centisome position: 45.42

GC content: 63.7

Gene sequence:

>810_bases
ATGATGGAATCGATCAAGAAGCTGCGCGAGCTGACCGGCGCGGGCATGATGGACGTGAAAAAGGCCCTGGCGGATGCCGG
GAACGACGAAGAAAAAGCGATTGCGCTGCTGCGCGAACGCGGCATTGTCAAGGCCGCCAAGAAGGCCGACCGCGAGGCGA
AGGAAGGGCTGGTGCGCTTCGTCGTGGACGGCAACAGGGCCGCGATGGTCGAGGTGAACAGCGAAACTGACTTTGTCGCG
CGCAACTCTGACTTCCAGGCACTCGTCGAACAGGTTGCGCAAGCGGCGCTGCGAGCCGGGACCAACAACGTTGAAGAGCT
GCGCAACTTCACGCTGGACAATGGCGAGACCGTTGGCAACGCTGTGGCGGCGGCGGCGGGCAAGATCGGCGAGAACCTGG
TGCTCAACCGCGTGGCCTACATTGACGCTGGCGAGGGCGAGCACGTGGCCGGGTACGTGCACTCCAACGGCAAGATCGGC
GTGCTGGTGGACCTCCTCGGCGGCACCGAGGCCCAGGCCAAGGATGTGGCGCTGCACGTGGCGGCCGAGCGGCCTCAGTA
CCTCAACCGCGACGAGGTGAACGCCGCAGACCTCGAAAAGGAGCGCGAGATCCTCACCAACAAGGCGCTGAACGAGGGCA
AGCCCCAACAGATCGTGGACAAGATCGTCCAGGGGCAGATCGGCAAGTTCTACGAGGAGCGCGTGCTGCCCGAGCAGAAG
TTCGTGAAGGACAACAGCGTGACCGTGGGACAGTACCTGGGGAACGCTCAGGTCAAGCGCTTCGTGCGCTTTGAGGTCGG
CGCGCAATGA

Upstream 100 bases:

>100_bases
GCCGCAGCTAAGCTCCCCCCGTTCCACCTTTCGGGGGCGTCCGGCGAAGTTCGGTCTGCCCCCATTTCAAGCCCCAATCC
ACCTTCTGGAGGTACACACC

Downstream 100 bases:

>100_bases
CCCACGCGGGGCGGCTCAGGGAAGCCGCCCCTTTCCTGGGCCGCTGCCCCTCTCTCCCTCGCCCGGCGGCCTCTTGGCGC
CGGGTCTTTTCTTGCCGCTC

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MMESIKKLRELTGAGMMDVKKALADAGNDEEKAIALLRERGIVKAAKKADREAKEGLVRFVVDGNRAAMVEVNSETDFVA
RNSDFQALVEQVAQAALRAGTNNVEELRNFTLDNGETVGNAVAAAAGKIGENLVLNRVAYIDAGEGEHVAGYVHSNGKIG
VLVDLLGGTEAQAKDVALHVAAERPQYLNRDEVNAADLEKEREILTNKALNEGKPQQIVDKIVQGQIGKFYEERVLPEQK
FVKDNSVTVGQYLGNAQVKRFVRFEVGAQ

Sequences:

>Translated_269_residues
MMESIKKLRELTGAGMMDVKKALADAGNDEEKAIALLRERGIVKAAKKADREAKEGLVRFVVDGNRAAMVEVNSETDFVA
RNSDFQALVEQVAQAALRAGTNNVEELRNFTLDNGETVGNAVAAAAGKIGENLVLNRVAYIDAGEGEHVAGYVHSNGKIG
VLVDLLGGTEAQAKDVALHVAAERPQYLNRDEVNAADLEKEREILTNKALNEGKPQQIVDKIVQGQIGKFYEERVLPEQK
FVKDNSVTVGQYLGNAQVKRFVRFEVGAQ
>Mature_269_residues
MMESIKKLRELTGAGMMDVKKALADAGNDEEKAIALLRERGIVKAAKKADREAKEGLVRFVVDGNRAAMVEVNSETDFVA
RNSDFQALVEQVAQAALRAGTNNVEELRNFTLDNGETVGNAVAAAAGKIGENLVLNRVAYIDAGEGEHVAGYVHSNGKIG
VLVDLLGGTEAQAKDVALHVAAERPQYLNRDEVNAADLEKEREILTNKALNEGKPQQIVDKIVQGQIGKFYEERVLPEQK
FVKDNSVTVGQYLGNAQVKRFVRFEVGAQ

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=283, Percent_Identity=32.8621908127208, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI291084500, Length=304, Percent_Identity=30.5921052631579, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI291084498, Length=95, Percent_Identity=48.4210526315789, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI291084502, Length=95, Percent_Identity=48.4210526315789, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1786366, Length=266, Percent_Identity=42.4812030075188, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17561440, Length=299, Percent_Identity=30.1003344481605, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19921466, Length=293, Percent_Identity=30.3754266211604, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_DEIGD (Q1IZI7)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_604516.1
- ProteinModelPortal:   Q1IZI7
- SMR:   Q1IZI7
- STRING:   Q1IZI7
- GeneID:   4057833
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_1048
- NMPDR:   fig|68909.1.peg.524
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q1IZI7
- ProtClustDB:   PRK09377
- BioCyc:   DGEO319795:DGEO_1048-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 29231; Mature: 29231

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMESIKKLRELTGAGMMDVKKALADAGNDEEKAIALLRERGIVKAAKKADREAKEGLVRF
CHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEE
VVDGNRAAMVEVNSETDFVARNSDFQALVEQVAQAALRAGTNNVEELRNFTLDNGETVGN
EEECCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHH
AVAAAAGKIGENLVLNRVAYIDAGEGEHVAGYVHSNGKIGVLVDLLGGTEAQAKDVALHV
HHHHHHHHHCCHHHHHHEEEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHEEEEE
AAERPQYLNRDEVNAADLEKEREILTNKALNEGKPQQIVDKIVQGQIGKFYEERVLPEQK
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
FVKDNSVTVGQYLGNAQVKRFVRFEVGAQ
HHCCCCEEHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MMESIKKLRELTGAGMMDVKKALADAGNDEEKAIALLRERGIVKAAKKADREAKEGLVRF
CHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEE
VVDGNRAAMVEVNSETDFVARNSDFQALVEQVAQAALRAGTNNVEELRNFTLDNGETVGN
EEECCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHH
AVAAAAGKIGENLVLNRVAYIDAGEGEHVAGYVHSNGKIGVLVDLLGGTEAQAKDVALHV
HHHHHHHHHCCHHHHHHEEEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHEEEEE
AAERPQYLNRDEVNAADLEKEREILTNKALNEGKPQQIVDKIVQGQIGKFYEERVLPEQK
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
FVKDNSVTVGQYLGNAQVKRFVRFEVGAQ
HHCCCCEEHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA