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The map label for this gene is fprA [H]

Identifier: 94985119

GI number: 94985119

Start: 1087266

End: 1088660

Strand: Reverse

Name: fprA [H]

Synonym: Dgeo_1014

Alternate gene names: 94985119

Gene position: 1088660-1087266 (Counterclockwise)

Preceding gene: 94985120

Following gene: 94985118

Centisome position: 44.13

GC content: 66.59

Gene sequence:

>1395_bases
ATGACGACCTCCTCTGTGCAGCACTTCACCCCCGAACGGCCCCTGCGCGTTGCCGTGATCGGCAGCGGTCCCAGCGGCGT
CTTCGCCACCGAGGCCCTGCTCAAGCAGACTGACATCCCCGTTCAGGTCGATGTGTTTGACCGCCTTCCTACCCCCTACG
GCCTGGTGCGCTACGGCGTCGCCCCTGACCACCTCACCATCAAGAGCGTGACCAAGGGTTTTGAGAAGACCCTCTCCGAC
CCGCGCGTCCGCTTCCTGGGCAACGTCGAGTTTGGGACCGATCTGACGTATGACGAGGCCCGCCGCCACTACGACGCCAT
CATCTATACCGTGGGGGCCAGCAGTGACCGCCGCCTGGGCATTCCCGGCGAAGATCTGCGAGGCTCCATGAGCGCAACCG
AGTTCGTGGCTTGGTACAACGGCCACCCCGACGCCGCCGCCCGCGAGATGGTGCTGAATGCGACCGGTGTCGCGGTGGTC
GGCGTGGGCAACGTGGCGCTGGATGTGAGCCGCATTCTGGCCAAGACCGTAGAGGAATTGCGGGAGAGTGATATCGCCGC
CCATGCATTGACGGCGCTGGAACAAAGCCCCGTGCGGGACGTGTGGGTGCTGGGCCGCCGCGGACCGCTGCAGGCCAAGT
TCACCACCAAGGAGCTGCGCGAGTTTGGGGAGCTGGAGGGGGCAGACCCCGTCGTGAACCCCGAGGAGATCGCGGTGAGT
GCGGCGGAAGAGGCCCAGGTCACCGACAATGTGGTGAAGAAGAATCTGGAAGTGCTGCGTGACTTTGCCGGGCGCACGCC
GGAAGGCAAGCCCCGGCGCGTGCATCTGCGGTTCCTGGTCTCGCCGGTCGAGATTCTGGACGACGGTCAGGGGCACGTGG
GCGGGCTGAAGGTGGAAAGAAACCGCCTGGATGAGAACGGCAACGCGGTGGGGACGGGCGAGTATGAGGTGCTGCCCGTC
CAGATGGTGCTGCGCTCGGTGGGCTACAAGGGTGTGGGGCTGCCCGGTGTCCCCTTCGATGAACAGCGCGGTGTGATTCC
CAACACGGAAGGCCGGGTGGAAGGCCGGACGGGCGAGTACACCGCCGGCTGGATCAAGCGCGGCCCTAGCGGCGTGATCG
GCACCAACCGCAAGGATGCAGTCGACACCGTGGCGCAGCTGCTGGCCGATGCGCAAGCCGGCGCGCTCCCCCACGCAAGT
CAGCCCAGCCGCGAGGCGGTGGATACGCTGCTGAGACAAAAGGGCGTGGAGGTGTACACCTTCGCGGACTGGCAGGCGCT
TGACGCCCATGAAGTCGCCCAGGGCCGGGCGCAGGGACGCCCCCGCGCCAAGGTCGTCCACAAGCACGAGATGTTGCAGC
ACCGCCAGCGGGAGATGCAGCAGGCCGAAGGCTGA

Upstream 100 bases:

>100_bases
TTGTTGTGGGCAGTTATGGTGGACGCGGCGACCGAATCCTGAGCGCATTCGTCCAGATTCAAACGACCAGGTTTCCGGTC
CTGCCCGCTAGACTCGCCTT

Downstream 100 bases:

>100_bases
AGTCGGCCGGGGCAGAGCGCAGCGGGCAGGGAGAAGCGCCGAGCCGCTGCGCTCTGCCATACTCGCCCCCATGCAGAGCA
AGCAGGCCCCAGATACGGAG

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTTSSVQHFTPERPLRVAVIGSGPSGVFATEALLKQTDIPVQVDVFDRLPTPYGLVRYGVAPDHLTIKSVTKGFEKTLSD
PRVRFLGNVEFGTDLTYDEARRHYDAIIYTVGASSDRRLGIPGEDLRGSMSATEFVAWYNGHPDAAAREMVLNATGVAVV
GVGNVALDVSRILAKTVEELRESDIAAHALTALEQSPVRDVWVLGRRGPLQAKFTTKELREFGELEGADPVVNPEEIAVS
AAEEAQVTDNVVKKNLEVLRDFAGRTPEGKPRRVHLRFLVSPVEILDDGQGHVGGLKVERNRLDENGNAVGTGEYEVLPV
QMVLRSVGYKGVGLPGVPFDEQRGVIPNTEGRVEGRTGEYTAGWIKRGPSGVIGTNRKDAVDTVAQLLADAQAGALPHAS
QPSREAVDTLLRQKGVEVYTFADWQALDAHEVAQGRAQGRPRAKVVHKHEMLQHRQREMQQAEG

Sequences:

>Translated_464_residues
MTTSSVQHFTPERPLRVAVIGSGPSGVFATEALLKQTDIPVQVDVFDRLPTPYGLVRYGVAPDHLTIKSVTKGFEKTLSD
PRVRFLGNVEFGTDLTYDEARRHYDAIIYTVGASSDRRLGIPGEDLRGSMSATEFVAWYNGHPDAAAREMVLNATGVAVV
GVGNVALDVSRILAKTVEELRESDIAAHALTALEQSPVRDVWVLGRRGPLQAKFTTKELREFGELEGADPVVNPEEIAVS
AAEEAQVTDNVVKKNLEVLRDFAGRTPEGKPRRVHLRFLVSPVEILDDGQGHVGGLKVERNRLDENGNAVGTGEYEVLPV
QMVLRSVGYKGVGLPGVPFDEQRGVIPNTEGRVEGRTGEYTAGWIKRGPSGVIGTNRKDAVDTVAQLLADAQAGALPHAS
QPSREAVDTLLRQKGVEVYTFADWQALDAHEVAQGRAQGRPRAKVVHKHEMLQHRQREMQQAEG
>Mature_463_residues
TTSSVQHFTPERPLRVAVIGSGPSGVFATEALLKQTDIPVQVDVFDRLPTPYGLVRYGVAPDHLTIKSVTKGFEKTLSDP
RVRFLGNVEFGTDLTYDEARRHYDAIIYTVGASSDRRLGIPGEDLRGSMSATEFVAWYNGHPDAAAREMVLNATGVAVVG
VGNVALDVSRILAKTVEELRESDIAAHALTALEQSPVRDVWVLGRRGPLQAKFTTKELREFGELEGADPVVNPEEIAVSA
AEEAQVTDNVVKKNLEVLRDFAGRTPEGKPRRVHLRFLVSPVEILDDGQGHVGGLKVERNRLDENGNAVGTGEYEVLPVQ
MVLRSVGYKGVGLPGVPFDEQRGVIPNTEGRVEGRTGEYTAGWIKRGPSGVIGTNRKDAVDTVAQLLADAQAGALPHASQ
PSREAVDTLLRQKGVEVYTFADWQALDAHEVAQGRAQGRPRAKVVHKHEMLQHRQREMQQAEG

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=466, Percent_Identity=42.7038626609442, Blast_Score=343, Evalue=3e-94,
Organism=Homo sapiens, GI111118983, Length=472, Percent_Identity=42.1610169491525, Blast_Score=337, Evalue=2e-92,
Organism=Escherichia coli, GI87082180, Length=164, Percent_Identity=31.0975609756098, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788811, Length=350, Percent_Identity=25.1428571428571, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17543860, Length=452, Percent_Identity=34.2920353982301, Blast_Score=244, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6320584, Length=498, Percent_Identity=30.5220883534137, Blast_Score=235, Evalue=1e-62,
Organism=Drosophila melanogaster, GI17137178, Length=460, Percent_Identity=37.8260869565217, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24665547, Length=156, Percent_Identity=31.4102564102564, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665543, Length=156, Percent_Identity=31.4102564102564, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574881, Length=156, Percent_Identity=31.4102564102564, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24665539, Length=156, Percent_Identity=31.4102564102564, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 50561; Mature: 50429

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSSVQHFTPERPLRVAVIGSGPSGVFATEALLKQTDIPVQVDVFDRLPTPYGLVRYGV
CCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEHHHCCCCCHHHEEECC
APDHLTIKSVTKGFEKTLSDPRVRFLGNVEFGTDLTYDEARRHYDAIIYTVGASSDRRLG
CCCCEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHEEEEEEEECCCCCCCCC
IPGEDLRGSMSATEFVAWYNGHPDAAAREMVLNATGVAVVGVGNVALDVSRILAKTVEEL
CCCHHHCCCCCHHHEEEEECCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH
RESDIAAHALTALEQSPVRDVWVLGRRGPLQAKFTTKELREFGELEGADPVVNPEEIAVS
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECHHHHHHHHCCCCCCCCCCHHHHEEE
AAEEAQVTDNVVKKNLEVLRDFAGRTPEGKPRRVHLRFLVSPVEILDDGQGHVGGLKVER
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECHHHHHCCCCCCCCCEEEEH
NRLDENGNAVGTGEYEVLPVQMVLRSVGYKGVGLPGVPFDEQRGVIPNTEGRVEGRTGEY
HHCCCCCCEEECCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TAGWIKRGPSGVIGTNRKDAVDTVAQLLADAQAGALPHASQPSREAVDTLLRQKGVEVYT
CCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEE
FADWQALDAHEVAQGRAQGRPRAKVVHKHEMLQHRQREMQQAEG
ECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTSSVQHFTPERPLRVAVIGSGPSGVFATEALLKQTDIPVQVDVFDRLPTPYGLVRYGV
CCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEHHHCCCCCHHHEEECC
APDHLTIKSVTKGFEKTLSDPRVRFLGNVEFGTDLTYDEARRHYDAIIYTVGASSDRRLG
CCCCEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHEEEEEEEECCCCCCCCC
IPGEDLRGSMSATEFVAWYNGHPDAAAREMVLNATGVAVVGVGNVALDVSRILAKTVEEL
CCCHHHCCCCCHHHEEEEECCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH
RESDIAAHALTALEQSPVRDVWVLGRRGPLQAKFTTKELREFGELEGADPVVNPEEIAVS
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECHHHHHHHHCCCCCCCCCCHHHHEEE
AAEEAQVTDNVVKKNLEVLRDFAGRTPEGKPRRVHLRFLVSPVEILDDGQGHVGGLKVER
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECHHHHHCCCCCCCCCEEEEH
NRLDENGNAVGTGEYEVLPVQMVLRSVGYKGVGLPGVPFDEQRGVIPNTEGRVEGRTGEY
HHCCCCCCEEECCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TAGWIKRGPSGVIGTNRKDAVDTVAQLLADAQAGALPHASQPSREAVDTLLRQKGVEVYT
CCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEE
FADWQALDAHEVAQGRAQGRPRAKVVHKHEMLQHRQREMQQAEG
ECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]