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The map label for this gene is prmA

Identifier: 94984946

GI number: 94984946

Start: 898840

End: 899679

Strand: Reverse

Name: prmA

Synonym: Dgeo_0839

Alternate gene names: 94984946

Gene position: 899679-898840 (Counterclockwise)

Preceding gene: 94984951

Following gene: 94984945

Centisome position: 36.47

GC content: 70.36

Gene sequence:

>840_bases
ATGCTCGTGTATCACCTGCCCGGCACCCTCGATACCCGCGAAGCCGACCTCGACCTGCTGTGGGCGGCGGGCGCCACCGG
TCTGGAGGAGCGCGGCGGCGTCATCCGCGCCTACTTCGACACCCGGACCGAGCTGCCACCCCAGGTCTCCGACGGTGAAT
GGCGCGAGGAGGCCGACCAGGACTGGCTGGCCGAGTTCAAACGAACGCTGCGCCCGGTGCGGGCGGGCCGCGTGACCATC
GTGCCGCCGTGGTTGCGGGAGGAGGTGGAGGCCGGGCAGCTCCCGCTGGTGATCGAGCCGGGAATGGCCTTTGGGACTGG
GCACCACGCGACCACCCGGCTGGCGGTGGAGGCTCTCTCGGCCCTCAATCTCGCCACCCTCGGCCCGCGAGGAACCGGGG
CGCGGGTGCTGGACGTGGGAACCGGGAGCGGCGTGCTGGCGATTGCAGCGGCGCTGCTGGGGGCCGGCTTTGCCCTCGGG
GTGGACATCGACCCGATCACCATTCCGATTGCGCGCGAGAACGCGCAGATCAACGGTATCCCGGCGAGCCGCGTGCGTTT
CGCGGAGGGCACCCTCGGGGCAGATCCCCTCACCTTCCCTGATGAGGGCGTGGACACCTACGACGTGGTGGTGGCGAACC
TCTATGCCGAACTCCATGACCTGCTGGCCGGAGAGTACGCGGCCCATCTGGTGCCGGGTGGCGCCCTGATCCTGACCGGT
ATCCTGACTGTCAAGCTGCCGCTGGTGCACGCGGCGCTGGACCGCGAGGGCTTTACGAACGTGCAGGAAACGCTGGACGG
CGAGTGGGCGCTGGTGACCGCCCGCGCGCCGCTCGGGTGA

Upstream 100 bases:

>100_bases
GATGGCTGTTCTGGCGTCCTGGTTGTGTTCATCCTTCAGAAGCAGAAGGTCATCTGAAGACGTTTTCTAAAGACTCCCCC
CAGGCCCTAGACTCCCGGAT

Downstream 100 bases:

>100_bases
GGCGCACATGGCTCCTCACCGCGTTCGGGTGGACACCCTCGCGCCGGCAATGACCCTCGGCCCGCGCGAAACGCGGCACC
TGCACGTGCTGCGCCTGCGC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MLVYHLPGTLDTREADLDLLWAAGATGLEERGGVIRAYFDTRTELPPQVSDGEWREEADQDWLAEFKRTLRPVRAGRVTI
VPPWLREEVEAGQLPLVIEPGMAFGTGHHATTRLAVEALSALNLATLGPRGTGARVLDVGTGSGVLAIAAALLGAGFALG
VDIDPITIPIARENAQINGIPASRVRFAEGTLGADPLTFPDEGVDTYDVVVANLYAELHDLLAGEYAAHLVPGGALILTG
ILTVKLPLVHAALDREGFTNVQETLDGEWALVTARAPLG

Sequences:

>Translated_279_residues
MLVYHLPGTLDTREADLDLLWAAGATGLEERGGVIRAYFDTRTELPPQVSDGEWREEADQDWLAEFKRTLRPVRAGRVTI
VPPWLREEVEAGQLPLVIEPGMAFGTGHHATTRLAVEALSALNLATLGPRGTGARVLDVGTGSGVLAIAAALLGAGFALG
VDIDPITIPIARENAQINGIPASRVRFAEGTLGADPLTFPDEGVDTYDVVVANLYAELHDLLAGEYAAHLVPGGALILTG
ILTVKLPLVHAALDREGFTNVQETLDGEWALVTARAPLG
>Mature_279_residues
MLVYHLPGTLDTREADLDLLWAAGATGLEERGGVIRAYFDTRTELPPQVSDGEWREEADQDWLAEFKRTLRPVRAGRVTI
VPPWLREEVEAGQLPLVIEPGMAFGTGHHATTRLAVEALSALNLATLGPRGTGARVLDVGTGSGVLAIAAALLGAGFALG
VDIDPITIPIARENAQINGIPASRVRFAEGTLGADPLTFPDEGVDTYDVVVANLYAELHDLLAGEYAAHLVPGGALILTG
ILTVKLPLVHAALDREGFTNVQETLDGEWALVTARAPLG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=159, Percent_Identity=40.8805031446541, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_DEIGD (Q1J043)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_604310.1
- ProteinModelPortal:   Q1J043
- SMR:   Q1J043
- STRING:   Q1J043
- GeneID:   4057958
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_0839
- NMPDR:   fig|68909.1.peg.2443
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   VPEWEDY
- ProtClustDB:   PRK00517
- BioCyc:   DGEO319795:DGEO_0839-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29572; Mature: 29572

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVYHLPGTLDTREADLDLLWAAGATGLEERGGVIRAYFDTRTELPPQVSDGEWREEADQ
CEEEECCCCCCCCCCCEEEEEECCCCCHHHCCCEEEEEECCCCCCCCCCCCCCHHHHCCH
DWLAEFKRTLRPVRAGRVTIVPPWLREEVEAGQLPLVIEPGMAFGTGHHATTRLAVEALS
HHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCEEECCCCEECCCCHHHHHHHHHHHH
ALNLATLGPRGTGARVLDVGTGSGVLAIAAALLGAGFALGVDIDPITIPIARENAQINGI
HHHHEECCCCCCCCEEEEECCCCCHHHHHHHHHHCCEEEECCCCCEEEEEECCCCEECCC
PASRVRFAEGTLGADPLTFPDEGVDTYDVVVANLYAELHDLLAGEYAAHLVPGGALILTG
CHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ILTVKLPLVHAALDREGFTNVQETLDGEWALVTARAPLG
HHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEECCCCC
>Mature Secondary Structure
MLVYHLPGTLDTREADLDLLWAAGATGLEERGGVIRAYFDTRTELPPQVSDGEWREEADQ
CEEEECCCCCCCCCCCEEEEEECCCCCHHHCCCEEEEEECCCCCCCCCCCCCCHHHHCCH
DWLAEFKRTLRPVRAGRVTIVPPWLREEVEAGQLPLVIEPGMAFGTGHHATTRLAVEALS
HHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCEEECCCCEECCCCHHHHHHHHHHHH
ALNLATLGPRGTGARVLDVGTGSGVLAIAAALLGAGFALGVDIDPITIPIARENAQINGI
HHHHEECCCCCCCCEEEEECCCCCHHHHHHHHHHCCEEEECCCCCEEEEEECCCCEECCC
PASRVRFAEGTLGADPLTFPDEGVDTYDVVVANLYAELHDLLAGEYAAHLVPGGALILTG
CHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ILTVKLPLVHAALDREGFTNVQETLDGEWALVTARAPLG
HHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA