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The map label for this gene is sbcC [H]

Identifier: 94984930

GI number: 94984930

Start: 879944

End: 882676

Strand: Reverse

Name: sbcC [H]

Synonym: Dgeo_0823

Alternate gene names: 94984930

Gene position: 882676-879944 (Counterclockwise)

Preceding gene: 94984931

Following gene: 94984923

Centisome position: 35.78

GC content: 68.72

Gene sequence:

>2733_bases
ATGAGGCCCCTTTCCCTCGAACTTCAGGGCTTCACCGCCTTTCGGCAGCACACCACCCTCGACTTTTCCGACCTGGAGCT
GTTCGCGCTGGTGGGGCCGACAGGCAGCGGCAAAAGCAGCCTGCTGGACGCGATGACCTTTGCGCTGTACGGCACGACGC
CGCGGCTAGGAAGCACCGGGCTAGACGCGCTGATCTCGCAGGGCGAGCGGGGGCTGTCGGTCAGCCTAACCTTTGAGGTG
GGCGGCGAGACGTACCGGGTGGCGCGCTCCAAGGGCCGGCGCCAGGCCGAGAACGAAGTGCGGCTGGAGCGGCGTGAGGA
GGGGCGCTGGGTCAACCTCAGTGACGGCGGCACCAAAGCGGTGAATGACCGCATTCGCCGGGTGGTGGGGTTGGACTTTC
GAACCTTCGCGCGCAGCGTGCTGCTGCCGCAGGGCGAATTCAGCCGGCTGCTGCACGGCACCGGCAAGGAGCGCCAGGCG
CTGCTGGGCGAGCTGATGGGCCTAGACCATGTGAAGGCGATGCACGCCTTTGCGGGGGAACGCGCCAAGGAATTCAAGCA
TACGCTGGGCAGCCTACACGCGCTGCTGGAGGGCGAATACGCCGGTGTGACCGAGGCGGCGGTCCGGGCCTTGCGGGCCG
AACGCGAAACGGTGGAGGCCGAAGCCGAGCACCTGCAAGACACACGGGAACAGCTCCAGGGGCAGGTAAACCGCCTGCGC
GTGTTGGAGGGCGTCTGGACCACCCGCGAGAACACTGCGCGCCGCCTGGGCATCCTCGAAGCCCGAGCGGCAAACGTGCG
CGAGGGGGACGAGCGAGCAGCGCGGGCACGGCGGGTGGCGGGCGTGCTGCCGCTGCTGGACGCTGCCGAGCGCGCCCGCA
TTGCGGCGGCGCGGGAAGCGGAGGAAGCCCGCCGCGCCGCAGAGGCTGAGGCAGTGGCCCGCCGGGCGGTGGAGGTGGCA
GAGGCGGCGCTGGAAGCGGCCCGGGAGGCCGAGGCCCGCATTCCTGAGCTGGAGGCGCGAGCCGACGCGCTGCGCGAGGC
CGAGGCCGACGCAGCCCGCCTGAGGCGCGCGGGAGGCACCCCGCAAACCACCCATCCCTCTCCCCTTCCCTGGGATGAGG
ACGCGCACTTCGCCGCTCGCGAAGCAGCCCAGAAGCTGGAAAAGCTGCGGCAGGAGCGCATCCAACTGGAAGCGCAGAAG
GCCGCGCTGGAAGCGGGCCGCGAACGACAAAAGGCCGAGCAAGCGCAGCAGCAAACGCTCCAGCAAGAACAACGTCGGGT
CGAACGCGAGGGCAAGCAGGCCAAGGCCGACCACGACCGGGCGCAGGCAGAGTGGCAGGCTGCGCGGCTGACAGCGGGCC
TGAGTGCCTACCGCGCTCACCTGCATGTGGGTGAACCCTGCCCGCTGTGTGAGCAGACGGTGCGGGTGCTGCCGCAAGCA
TCCGCCGTGGATCTTGCCGCGCTGGAACGGCAGGTGACGGCGCTCCAGGGCACGCTCGAAAACCGCCGCCTACGCTACAA
GGAAATTGGGCTAGAACTCGTCAACCTGAAAAAATCCATCGAGGCCCGCAGCGCCGAGCTGGCCGACTGGGAGGCGGCAC
TGGAACAGCGAGAACTCGACCTGAGGCAGCTTGAGGCGCAGATCAGCGGCGATCCACACGACCTCGCGCTGCGCTTGCTG
GCTGGACTGGCGCAGCGGGTGCGGGCGGCGGGACCGGACCCAGCCCGTGAACGGCAGAAACGGCTGGTGGAGATCAAGAG
CATCCGCGACCGGCTGAATGAGGCGCAAACCGCGCTCGCCCGCGCGCAGAGTGCCCATGCGGCTTCAGCGGCCACCTTGA
CCTCGGCGGGAAATGCCGCCGGGAGCCGTTCCCGTGAGGCGCAGGACGCGCAGACCGCACTAGAGGAGGCCCTCGCCGCC
CTGGGGCTAGACGCCGCCCAGGCCCGCGCCGCCGCCCTCCCCGAAGCGGACATCGCCGCGCTGGAACAGGCTGCGCGCAG
CCACGCCGCGCAGGTCGAGCAACTCAAAGTCCAGCTCGCCGAACTGGACCGGCAACTGGGTCTGGAACCCTTTGATCCCG
CGCAGCTCCGCCAAGCCGAACGCGACCTGATCGCCACCGACGCCGCCCTCAGCCGGGTGCGCGAGCGGGCTGGGAGCCTG
GCCGAGCAGGAACGCAGCGCCCGTGAACGCCTGGGGCGCAAGGCGGAGATTGAGGCGCGAGCAAAGGACCTGGCCGCCAA
ACTGGACACCTGGCAGACACTCACGAACACGCTGCGGGCCAATGAGTTCCAGCAGTACCTCCTCGCGGAGGTGGAGGCGC
GACTGCTGACGGGAGCGGGTGCCCTGCTGTACGAGATCAGCGACGGGCGCTACCGCCTCGCCCTGGAGAACGGCGAGTAC
GTCGTACAGGACCTCTGGAATGCGGGCGAGACGCGCGGCGTAAAAACACTTTCTGGCGGTGAAACGTTCCTCGCGAGCCT
CAGTCTCGCCATCGCCCTCAGCGATTACTTGGCGGGAAACAAGATTCTGGGTGCTCTGTTTCTGGATGAGGGCTTCGGCA
CACTGGACCCGCAAGCACTCGAAGCTGTGGCGGGCGCACTGGAAAATCTGCGGACGCAGGGGCGAATGGTGGGTGTGGTC
ACCCACGTAGAGAGCCTTTCGGAACGGCTCCCCAGTCGCTTGGTCGTCACCAAGAGCGTGGCGGGAAGCAGCGTGCAGCG
GCTGGACGGGTGA

Upstream 100 bases:

>100_bases
CGTGAGGCAGACGAGGCCGCGCGGGGAGAAGCCGAAGAGGTGGTCGCATGATCCGCCGGGCCAGACGGCCACGCACCGCA
TCCGCACCCCGGAGGTGCTC

Downstream 100 bases:

>100_bases
ACGGCTGGACGGGTGAACACTGCCTTGCGGCAAGGAGACCTTTACCGCCCCACTGCCTCCTCGCCCTGCCGGATACTCAG
CACACGGCTCGCGCCGGTCT

Product: SMC protein-like protein

Products: 5'-phosphomonoesters [C]

Alternate protein names: NA

Number of amino acids: Translated: 910; Mature: 910

Protein sequence:

>910_residues
MRPLSLELQGFTAFRQHTTLDFSDLELFALVGPTGSGKSSLLDAMTFALYGTTPRLGSTGLDALISQGERGLSVSLTFEV
GGETYRVARSKGRRQAENEVRLERREEGRWVNLSDGGTKAVNDRIRRVVGLDFRTFARSVLLPQGEFSRLLHGTGKERQA
LLGELMGLDHVKAMHAFAGERAKEFKHTLGSLHALLEGEYAGVTEAAVRALRAERETVEAEAEHLQDTREQLQGQVNRLR
VLEGVWTTRENTARRLGILEARAANVREGDERAARARRVAGVLPLLDAAERARIAAAREAEEARRAAEAEAVARRAVEVA
EAALEAAREAEARIPELEARADALREAEADAARLRRAGGTPQTTHPSPLPWDEDAHFAAREAAQKLEKLRQERIQLEAQK
AALEAGRERQKAEQAQQQTLQQEQRRVEREGKQAKADHDRAQAEWQAARLTAGLSAYRAHLHVGEPCPLCEQTVRVLPQA
SAVDLAALERQVTALQGTLENRRLRYKEIGLELVNLKKSIEARSAELADWEAALEQRELDLRQLEAQISGDPHDLALRLL
AGLAQRVRAAGPDPARERQKRLVEIKSIRDRLNEAQTALARAQSAHAASAATLTSAGNAAGSRSREAQDAQTALEEALAA
LGLDAAQARAAALPEADIAALEQAARSHAAQVEQLKVQLAELDRQLGLEPFDPAQLRQAERDLIATDAALSRVRERAGSL
AEQERSARERLGRKAEIEARAKDLAAKLDTWQTLTNTLRANEFQQYLLAEVEARLLTGAGALLYEISDGRYRLALENGEY
VVQDLWNAGETRGVKTLSGGETFLASLSLAIALSDYLAGNKILGALFLDEGFGTLDPQALEAVAGALENLRTQGRMVGVV
THVESLSERLPSRLVVTKSVAGSSVQRLDG

Sequences:

>Translated_910_residues
MRPLSLELQGFTAFRQHTTLDFSDLELFALVGPTGSGKSSLLDAMTFALYGTTPRLGSTGLDALISQGERGLSVSLTFEV
GGETYRVARSKGRRQAENEVRLERREEGRWVNLSDGGTKAVNDRIRRVVGLDFRTFARSVLLPQGEFSRLLHGTGKERQA
LLGELMGLDHVKAMHAFAGERAKEFKHTLGSLHALLEGEYAGVTEAAVRALRAERETVEAEAEHLQDTREQLQGQVNRLR
VLEGVWTTRENTARRLGILEARAANVREGDERAARARRVAGVLPLLDAAERARIAAAREAEEARRAAEAEAVARRAVEVA
EAALEAAREAEARIPELEARADALREAEADAARLRRAGGTPQTTHPSPLPWDEDAHFAAREAAQKLEKLRQERIQLEAQK
AALEAGRERQKAEQAQQQTLQQEQRRVEREGKQAKADHDRAQAEWQAARLTAGLSAYRAHLHVGEPCPLCEQTVRVLPQA
SAVDLAALERQVTALQGTLENRRLRYKEIGLELVNLKKSIEARSAELADWEAALEQRELDLRQLEAQISGDPHDLALRLL
AGLAQRVRAAGPDPARERQKRLVEIKSIRDRLNEAQTALARAQSAHAASAATLTSAGNAAGSRSREAQDAQTALEEALAA
LGLDAAQARAAALPEADIAALEQAARSHAAQVEQLKVQLAELDRQLGLEPFDPAQLRQAERDLIATDAALSRVRERAGSL
AEQERSARERLGRKAEIEARAKDLAAKLDTWQTLTNTLRANEFQQYLLAEVEARLLTGAGALLYEISDGRYRLALENGEY
VVQDLWNAGETRGVKTLSGGETFLASLSLAIALSDYLAGNKILGALFLDEGFGTLDPQALEAVAGALENLRTQGRMVGVV
THVESLSERLPSRLVVTKSVAGSSVQRLDG
>Mature_910_residues
MRPLSLELQGFTAFRQHTTLDFSDLELFALVGPTGSGKSSLLDAMTFALYGTTPRLGSTGLDALISQGERGLSVSLTFEV
GGETYRVARSKGRRQAENEVRLERREEGRWVNLSDGGTKAVNDRIRRVVGLDFRTFARSVLLPQGEFSRLLHGTGKERQA
LLGELMGLDHVKAMHAFAGERAKEFKHTLGSLHALLEGEYAGVTEAAVRALRAERETVEAEAEHLQDTREQLQGQVNRLR
VLEGVWTTRENTARRLGILEARAANVREGDERAARARRVAGVLPLLDAAERARIAAAREAEEARRAAEAEAVARRAVEVA
EAALEAAREAEARIPELEARADALREAEADAARLRRAGGTPQTTHPSPLPWDEDAHFAAREAAQKLEKLRQERIQLEAQK
AALEAGRERQKAEQAQQQTLQQEQRRVEREGKQAKADHDRAQAEWQAARLTAGLSAYRAHLHVGEPCPLCEQTVRVLPQA
SAVDLAALERQVTALQGTLENRRLRYKEIGLELVNLKKSIEARSAELADWEAALEQRELDLRQLEAQISGDPHDLALRLL
AGLAQRVRAAGPDPARERQKRLVEIKSIRDRLNEAQTALARAQSAHAASAATLTSAGNAAGSRSREAQDAQTALEEALAA
LGLDAAQARAAALPEADIAALEQAARSHAAQVEQLKVQLAELDRQLGLEPFDPAQLRQAERDLIATDAALSRVRERAGSL
AEQERSARERLGRKAEIEARAKDLAAKLDTWQTLTNTLRANEFQQYLLAEVEARLLTGAGALLYEISDGRYRLALENGEY
VVQDLWNAGETRGVKTLSGGETFLASLSLAIALSDYLAGNKILGALFLDEGFGTLDPQALEAVAGALENLRTQGRMVGVV
THVESLSERLPSRLVVTKSVAGSSVQRLDG

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0419

COG function: function code L; ATPase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SMC family. SbcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786597, Length=532, Percent_Identity=28.1954887218045, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003395 [H]

Pfam domain/function: PF02463 SMC_N [H]

EC number: NA

Molecular weight: Translated: 99434; Mature: 99434

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLSLELQGFTAFRQHTTLDFSDLELFALVGPTGSGKSSLLDAMTFALYGTTPRLGSTG
CCCCEEEECCHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCC
LDALISQGERGLSVSLTFEVGGETYRVARSKGRRQAENEVRLERREEGRWVNLSDGGTKA
HHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHH
VNDRIRRVVGLDFRTFARSVLLPQGEFSRLLHGTGKERQALLGELMGLDHVKAMHAFAGE
HHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHH
RAKEFKHTLGSLHALLEGEYAGVTEAAVRALRAERETVEAEAEHLQDTREQLQGQVNRLR
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLEGVWTTRENTARRLGILEARAANVREGDERAARARRVAGVLPLLDAAERARIAAAREA
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEARRAAEAEAVARRAVEVAEAALEAAREAEARIPELEARADALREAEADAARLRRAGGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PQTTHPSPLPWDEDAHFAAREAAQKLEKLRQERIQLEAQKAALEAGRERQKAEQAQQQTL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQEQRRVEREGKQAKADHDRAQAEWQAARLTAGLSAYRAHLHVGEPCPLCEQTVRVLPQA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
SAVDLAALERQVTALQGTLENRRLRYKEIGLELVNLKKSIEARSAELADWEAALEQRELD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQLEAQISGDPHDLALRLLAGLAQRVRAAGPDPARERQKRLVEIKSIRDRLNEAQTALA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAQSAHAASAATLTSAGNAAGSRSREAQDAQTALEEALAALGLDAAQARAAALPEADIAA
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHH
LEQAARSHAAQVEQLKVQLAELDRQLGLEPFDPAQLRQAERDLIATDAALSRVRERAGSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEQERSARERLGRKAEIEARAKDLAAKLDTWQTLTNTLRANEFQQYLLAEVEARLLTGAG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ALLYEISDGRYRLALENGEYVVQDLWNAGETRGVKTLSGGETFLASLSLAIALSDYLAGN
EEEEEECCCEEEEEEECCCHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCC
KILGALFLDEGFGTLDPQALEAVAGALENLRTQGRMVGVVTHVESLSERLPSRLVVTKSV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEHHH
AGSSVQRLDG
CCCHHHHCCC
>Mature Secondary Structure
MRPLSLELQGFTAFRQHTTLDFSDLELFALVGPTGSGKSSLLDAMTFALYGTTPRLGSTG
CCCCEEEECCHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCC
LDALISQGERGLSVSLTFEVGGETYRVARSKGRRQAENEVRLERREEGRWVNLSDGGTKA
HHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHH
VNDRIRRVVGLDFRTFARSVLLPQGEFSRLLHGTGKERQALLGELMGLDHVKAMHAFAGE
HHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHH
RAKEFKHTLGSLHALLEGEYAGVTEAAVRALRAERETVEAEAEHLQDTREQLQGQVNRLR
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLEGVWTTRENTARRLGILEARAANVREGDERAARARRVAGVLPLLDAAERARIAAAREA
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEARRAAEAEAVARRAVEVAEAALEAAREAEARIPELEARADALREAEADAARLRRAGGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PQTTHPSPLPWDEDAHFAAREAAQKLEKLRQERIQLEAQKAALEAGRERQKAEQAQQQTL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQEQRRVEREGKQAKADHDRAQAEWQAARLTAGLSAYRAHLHVGEPCPLCEQTVRVLPQA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
SAVDLAALERQVTALQGTLENRRLRYKEIGLELVNLKKSIEARSAELADWEAALEQRELD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQLEAQISGDPHDLALRLLAGLAQRVRAAGPDPARERQKRLVEIKSIRDRLNEAQTALA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAQSAHAASAATLTSAGNAAGSRSREAQDAQTALEEALAALGLDAAQARAAALPEADIAA
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHH
LEQAARSHAAQVEQLKVQLAELDRQLGLEPFDPAQLRQAERDLIATDAALSRVRERAGSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEQERSARERLGRKAEIEARAKDLAAKLDTWQTLTNTLRANEFQQYLLAEVEARLLTGAG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ALLYEISDGRYRLALENGEYVVQDLWNAGETRGVKTLSGGETFLASLSLAIALSDYLAGN
EEEEEECCCEEEEEEECCCHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCC
KILGALFLDEGFGTLDPQALEAVAGALENLRTQGRMVGVVTHVESLSERLPSRLVVTKSV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEHHH
AGSSVQRLDG
CCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ribo- or deoxyribonucleic acids [C]

Specific reaction: ribo- or deoxyribonucleic acids = 5'-phosphomonoesters [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]