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The map label for this gene is ald [H]

Identifier: 94984878

GI number: 94984878

Start: 832810

End: 833916

Strand: Reverse

Name: ald [H]

Synonym: Dgeo_0771

Alternate gene names: 94984878

Gene position: 833916-832810 (Counterclockwise)

Preceding gene: 94984881

Following gene: 94984871

Centisome position: 33.8

GC content: 65.85

Gene sequence:

>1107_bases
ATGAAGATTGGGCTTCCGAAGGAAATCAAGGTCAAGGAAAATCGAGTGGCACTCACGCCCGGTGGGGTTGCCACGCTGAT
TCGGCGCGGGCATACGGTCACGGTAGAGCGTGGCGCGGGCGTCGGCAGCGGGATTCATGACAGCGAGTACGAGGCTGCGG
GCGCCGTGTTGGGCACGGCAGCGGAAGCCTGGGCTGCCGAAATGGTGGTGAAGGTGAAGGAACCGGTCCCCAGCGAGTAC
GCTTACCTCCGCCCTGACCTGCTGCTGTTCACGTACCTGCATCTGGCCGCCGACCGCCCGCTCACCGAGGCGCTGCTGGC
GGCGGGCACGACGGCCGTTGCCTATGAGACGGTGCAGCTCGAAGACGGCAGTCTCCCCCTCCTGACCCCCATGTCCGAGG
TCGCCGGACGCCTCAGCGTGCAGGCGGGTGCCTACTACCTCCAAAAGCCGGTGGGCGGACGTGGCGTGCTGCTTGGCGGC
GTGCCGGGCGTACAGCCGGGGCACGTGCTGATCGTGGGCGGTGGGGTCGTCGGCACAAACGCCGCGAAAATGGCCATGGG
GTTGGGGGCCAAGGTGACTGTGCTCGACGTGTCGCACCGCCGCCTGACCTATCTCGACGACGTATTCTTCGGCAAGCTCA
CCACCATGATGAGCAGCGAAGCCAACATCCGCGCGCTGCTGCCCGAGACTGACCTCCTGATCGGCGCGGTGCTGATTCCC
GGCGCCAAGGCCCCGCACCTCATCACTCGCGACATGCTGCCGCTGATGCAAGAAGGCAGCGTGATCGTCGATGTGGCGGT
GGACCAAGGCGGCTGCGTGGAGACGATCCACCCCACCACCCACGACGACCCGACCTACGTGGTCGATGGCGTCATTCATT
ACGGCGTGGCCAATATGCCCGGCGCGGTGCCGCGCACGAGTACCTTTGCCCTCACGAACGCCACCTTCCCCTATCTGCTG
CTGCTCGCGGATCAGGGCACCGGGGCACTGTTCCGCAACCCGGCGCTGATGCGAGGATTGAACACCTACCGGGGCAAGCT
GACCTATCAGGGCGTAGCAGAGGCGTTCGGAATGCCGTCCGTAGAGGCAGCAGCAGCGCTCGCGTAG

Upstream 100 bases:

>100_bases
CTGCTCGGCAATCCTCAGCAGCAAACCTCCTGCTAGCATTGCGGCACATTCAGCAGGTCTAGGCGGCTCGGCAAGGCTGG
CCGCGCAGCAGGAGTCAGGT

Downstream 100 bases:

>100_bases
ACAGCGAGCAAGGAGCGCCGGCAGATGTTCTGAAGGCATTCAGAGCGTGCAGAAGGGGGACCGACGACCAATCGGTCCCC
CACTCGAATGACAGGAACAA

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKIGLPKEIKVKENRVALTPGGVATLIRRGHTVTVERGAGVGSGIHDSEYEAAGAVLGTAAEAWAAEMVVKVKEPVPSEY
AYLRPDLLLFTYLHLAADRPLTEALLAAGTTAVAYETVQLEDGSLPLLTPMSEVAGRLSVQAGAYYLQKPVGGRGVLLGG
VPGVQPGHVLIVGGGVVGTNAAKMAMGLGAKVTVLDVSHRRLTYLDDVFFGKLTTMMSSEANIRALLPETDLLIGAVLIP
GAKAPHLITRDMLPLMQEGSVIVDVAVDQGGCVETIHPTTHDDPTYVVDGVIHYGVANMPGAVPRTSTFALTNATFPYLL
LLADQGTGALFRNPALMRGLNTYRGKLTYQGVAEAFGMPSVEAAAALA

Sequences:

>Translated_368_residues
MKIGLPKEIKVKENRVALTPGGVATLIRRGHTVTVERGAGVGSGIHDSEYEAAGAVLGTAAEAWAAEMVVKVKEPVPSEY
AYLRPDLLLFTYLHLAADRPLTEALLAAGTTAVAYETVQLEDGSLPLLTPMSEVAGRLSVQAGAYYLQKPVGGRGVLLGG
VPGVQPGHVLIVGGGVVGTNAAKMAMGLGAKVTVLDVSHRRLTYLDDVFFGKLTTMMSSEANIRALLPETDLLIGAVLIP
GAKAPHLITRDMLPLMQEGSVIVDVAVDQGGCVETIHPTTHDDPTYVVDGVIHYGVANMPGAVPRTSTFALTNATFPYLL
LLADQGTGALFRNPALMRGLNTYRGKLTYQGVAEAFGMPSVEAAAALA
>Mature_368_residues
MKIGLPKEIKVKENRVALTPGGVATLIRRGHTVTVERGAGVGSGIHDSEYEAAGAVLGTAAEAWAAEMVVKVKEPVPSEY
AYLRPDLLLFTYLHLAADRPLTEALLAAGTTAVAYETVQLEDGSLPLLTPMSEVAGRLSVQAGAYYLQKPVGGRGVLLGG
VPGVQPGHVLIVGGGVVGTNAAKMAMGLGAKVTVLDVSHRRLTYLDDVFFGKLTTMMSSEANIRALLPETDLLIGAVLIP
GAKAPHLITRDMLPLMQEGSVIVDVAVDQGGCVETIHPTTHDDPTYVVDGVIHYGVANMPGAVPRTSTFALTNATFPYLL
LLADQGTGALFRNPALMRGLNTYRGKLTYQGVAEAFGMPSVEAAAALA

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=345, Percent_Identity=31.8840579710145, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI122939153, Length=345, Percent_Identity=31.8840579710145, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1787887, Length=378, Percent_Identity=30.1587301587302, Blast_Score=139, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17550456, Length=365, Percent_Identity=30.6849315068493, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 38503; Mature: 38503

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGLPKEIKVKENRVALTPGGVATLIRRGHTVTVERGAGVGSGIHDSEYEAAGAVLGTA
CCCCCCCCEEEECCEEEECCCHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
AEAWAAEMVVKVKEPVPSEYAYLRPDLLLFTYLHLAADRPLTEALLAAGTTAVAYETVQL
HHHHHHHHHHEECCCCCCCHHHHCHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEEEEEE
EDGSLPLLTPMSEVAGRLSVQAGAYYLQKPVGGRGVLLGGVPGVQPGHVLIVGGGVVGTN
CCCCCCEECCHHHHHHHEEEECCCEEEECCCCCCEEEEECCCCCCCCEEEEECCCEECCC
AAKMAMGLGAKVTVLDVSHRRLTYLDDVFFGKLTTMMSSEANIRALLPETDLLIGAVLIP
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHEEEEEEEC
GAKAPHLITRDMLPLMQEGSVIVDVAVDQGGCVETIHPTTHDDPTYVVDGVIHYGVANMP
CCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCCCEEEHHHHHHCCCCCC
GAVPRTSTFALTNATFPYLLLLADQGTGALFRNPALMRGLNTYRGKLTYQGVAEAFGMPS
CCCCCCCEEEEECCCCEEEEEEECCCCCCEECCCHHHHCCHHHCCEEEECHHHHHHCCCC
VEAAAALA
HHHHHHCC
>Mature Secondary Structure
MKIGLPKEIKVKENRVALTPGGVATLIRRGHTVTVERGAGVGSGIHDSEYEAAGAVLGTA
CCCCCCCCEEEECCEEEECCCHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
AEAWAAEMVVKVKEPVPSEYAYLRPDLLLFTYLHLAADRPLTEALLAAGTTAVAYETVQL
HHHHHHHHHHEECCCCCCCHHHHCHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEEEEEE
EDGSLPLLTPMSEVAGRLSVQAGAYYLQKPVGGRGVLLGGVPGVQPGHVLIVGGGVVGTN
CCCCCCEECCHHHHHHHEEEECCCEEEECCCCCCEEEEECCCCCCCCEEEEECCCEECCC
AAKMAMGLGAKVTVLDVSHRRLTYLDDVFFGKLTTMMSSEANIRALLPETDLLIGAVLIP
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHEEEEEEEC
GAKAPHLITRDMLPLMQEGSVIVDVAVDQGGCVETIHPTTHDDPTYVVDGVIHYGVANMP
CCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCCCEEEHHHHHHCCCCCC
GAVPRTSTFALTNATFPYLLLLADQGTGALFRNPALMRGLNTYRGKLTYQGVAEAFGMPS
CCCCCCCEEEEECCCCEEEEEEECCCCCCEECCCHHHHCCHHHCCEEEECHHHHHHCCCC
VEAAAALA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA