Click here to switch to the map view.

The map label for this gene is pyrR [H]

Identifier: 94984611

GI number: 94984611

Start: 523467

End: 524021

Strand: Reverse

Name: pyrR [H]

Synonym: Dgeo_0504

Alternate gene names: 94984611

Gene position: 524021-523467 (Counterclockwise)

Preceding gene: 94984615

Following gene: 94984610

Centisome position: 21.24

GC content: 65.59

Gene sequence:

>555_bases
ATGCCGGTGACGCCCAAGGCCACTATTTTGACCGCCGAGGAACTGCGCCGGGCGCTCACCCGCATCGCGCACGAGATCAT
CGAGCGCAACAAGGGGGCAGAGAATCTCGCGCTGATCGGGATTCACACGCGCGGAATTCCGCTGGCCCAGCGGCTGGCGG
AGAAACTGGGTGACCTGGAAGGCGTGAACGTGCCGACCGGGATGCTCGACATCACGCTGTACCGCGATGACCTCTCGGAA
GTCGCCCATCAGCCGATCATCCGCGAGACGCACGTGCCCTTCGATCTAGGGCAGCGCCGGGTGGTGCTGGTGGACGATGT
GCTGTTTACCGGACGCACCGTGCGCGCCGCACTCGACGCCCTGATTGACCTGGGCCGCCCGGCAGGCATCCAGCTGGCCG
TCTTGGTGGACCGCGGACACCGTGAACTCCCCATCCGTGCGGATTACGTCGGCAAGAACCTGCCCACGTCACGCAGCGAG
ATGGTCAAGGTGCGGCTCGCGGAGACGGACGGCGTGGACCTGGTGGAACTGCACGATCTGGAGGAGCGGAGATGA

Upstream 100 bases:

>100_bases
GCACCCGCCCCGTGAGGCAGGAGAAGGAGCAGAAGATGCAAGGGACATGGCTGAGCCGACAGCGCGGGCTGGACGGCATT
TTTTCTGAACAGAAGGCGGA

Downstream 100 bases:

>100_bases
CGGTCCTCGCGCCTCCCCGCCCCCGCAGCCTGCTGGACTTCCAAGACTGGCTGCCCGAGCGCCTCAGCGCCCTGCTGGAC
AATGCCGACACCATGCACCA

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MPVTPKATILTAEELRRALTRIAHEIIERNKGAENLALIGIHTRGIPLAQRLAEKLGDLEGVNVPTGMLDITLYRDDLSE
VAHQPIIRETHVPFDLGQRRVVLVDDVLFTGRTVRAALDALIDLGRPAGIQLAVLVDRGHRELPIRADYVGKNLPTSRSE
MVKVRLAETDGVDLVELHDLEERR

Sequences:

>Translated_184_residues
MPVTPKATILTAEELRRALTRIAHEIIERNKGAENLALIGIHTRGIPLAQRLAEKLGDLEGVNVPTGMLDITLYRDDLSE
VAHQPIIRETHVPFDLGQRRVVLVDDVLFTGRTVRAALDALIDLGRPAGIQLAVLVDRGHRELPIRADYVGKNLPTSRSE
MVKVRLAETDGVDLVELHDLEERR
>Mature_183_residues
PVTPKATILTAEELRRALTRIAHEIIERNKGAENLALIGIHTRGIPLAQRLAEKLGDLEGVNVPTGMLDITLYRDDLSEV
AHQPIIRETHVPFDLGQRRVVLVDDVLFTGRTVRAALDALIDLGRPAGIQLAVLVDRGHRELPIRADYVGKNLPTSRSEM
VKVRLAETDGVDLVELHDLEERR

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 20463; Mature: 20332

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVTPKATILTAEELRRALTRIAHEIIERNKGAENLALIGIHTRGIPLAQRLAEKLGDLE
CCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCC
GVNVPTGMLDITLYRDDLSEVAHQPIIRETHVPFDLGQRRVVLVDDVLFTGRTVRAALDA
CCCCCCCEEEEEEEHHHHHHHHHCCCHHHCCCCCCCCCCEEEEEECHHHCCHHHHHHHHH
LIDLGRPAGIQLAVLVDRGHRELPIRADYVGKNLPTSRSEMVKVRLAETDGVDLVELHDL
HHHCCCCCCEEEEEEEECCCCCCCEEHHHCCCCCCCCCCCEEEEEEECCCCCCEEEECCC
EERR
CCCC
>Mature Secondary Structure 
PVTPKATILTAEELRRALTRIAHEIIERNKGAENLALIGIHTRGIPLAQRLAEKLGDLE
CCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCC
GVNVPTGMLDITLYRDDLSEVAHQPIIRETHVPFDLGQRRVVLVDDVLFTGRTVRAALDA
CCCCCCCEEEEEEEHHHHHHHHHCCCHHHCCCCCCCCCCEEEEEECHHHCCHHHHHHHHH
LIDLGRPAGIQLAVLVDRGHRELPIRADYVGKNLPTSRSEMVKVRLAETDGVDLVELHDL
HHHCCCCCCEEEEEEEECCCCCCCEEHHHCCCCCCCCCCCEEEEEEECCCCCCEEEECCC
EERR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA