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The map label for this gene is moaC

Identifier: 94984446

GI number: 94984446

Start: 340114

End: 340608

Strand: Reverse

Name: moaC

Synonym: Dgeo_0338

Alternate gene names: 94984446

Gene position: 340608-340114 (Counterclockwise)

Preceding gene: 94984447

Following gene: 94984445

Centisome position: 13.81

GC content: 67.27

Gene sequence:

>495_bases
GTGAGCCCAGAGCAGGACACCTCCCCAGAGCTGACCCATTTCCGTGATGGTCTGCCGCGCATGGTCGATGTCACCGAAAA
GGCGGCCACCCTGCGCACTGCCACCGCTGAGGGCTGGGTGCGACTCCCTCCCGAGGCCCGCGCGGCGCTGGAGGGAGGAA
CCTCTCCGAAGGGGGATCCGCTGACGGTCGCGCGGCTGGGGGGCCTCGCGGGCAGCAAGCGCACGGCCGACTTGGTGCTG
CTCTGCCACCCCATTCCTGTGACCGGCGCCGATGTTCGCGTCACGCTAGAGAAAGCGGGGGTGCGGATTGTGGCGACCGT
GCGGACAACTGCCCCGACGGGCGTGGAGATGGAGGCCCTGACCGCGGTCAGTGTGGCCGCCCTGAACGTGTACGACATGC
TGAAGGCTGCCAGCAAGGCGATCGAGATCACCGGCGTGCGGCTGCTTTCCAAAACCGGTGGCAAGAGTGGCGATTACACT
GCACCGGACACTTGA

Upstream 100 bases:

>100_bases
AGGAGATCGACGACGCGCTGGGTACGCCTGAGGGATTGGCGCACGCCCGGCAGAATCCCTTCGCCGCTCTGCGCGACCTT
AACCTCCCCGAGGACTGAGG

Downstream 100 bases:

>100_bases
CCGGAAACTTTCTCGTTCCCTTCAACGTAAAAGGAATGTATGGGCGTGAAGGGGTGCGATCCCGAGCTGGATCTGCTGCA
CCGCGAGGCGGACGGTGACC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSPEQDTSPELTHFRDGLPRMVDVTEKAATLRTATAEGWVRLPPEARAALEGGTSPKGDPLTVARLGGLAGSKRTADLVL
LCHPIPVTGADVRVTLEKAGVRIVATVRTTAPTGVEMEALTAVSVAALNVYDMLKAASKAIEITGVRLLSKTGGKSGDYT
APDT

Sequences:

>Translated_164_residues
MSPEQDTSPELTHFRDGLPRMVDVTEKAATLRTATAEGWVRLPPEARAALEGGTSPKGDPLTVARLGGLAGSKRTADLVL
LCHPIPVTGADVRVTLEKAGVRIVATVRTTAPTGVEMEALTAVSVAALNVYDMLKAASKAIEITGVRLLSKTGGKSGDYT
APDT
>Mature_163_residues
SPEQDTSPELTHFRDGLPRMVDVTEKAATLRTATAEGWVRLPPEARAALEGGTSPKGDPLTVARLGGLAGSKRTADLVLL
CHPIPVTGADVRVTLEKAGVRIVATVRTTAPTGVEMEALTAVSVAALNVYDMLKAASKAIEITGVRLLSKTGGKSGDYTA
PDT

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=153, Percent_Identity=48.3660130718954, Blast_Score=129, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=40.9395973154362, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28574490, Length=149, Percent_Identity=52.3489932885906, Blast_Score=129, Evalue=8e-31,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=54.014598540146, Blast_Score=128, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_DEIGD (Q1J1J3)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_603810.1
- ProteinModelPortal:   Q1J1J3
- SMR:   Q1J1J3
- STRING:   Q1J1J3
- GeneID:   4057887
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_0338
- NMPDR:   fig|68909.1.peg.455
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- PhylomeDB:   Q1J1J3
- ProtClustDB:   PRK09364
- BioCyc:   DGEO319795:DGEO_0338-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17062; Mature: 16931

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: ACT_SITE 132-132

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPEQDTSPELTHFRDGLPRMVDVTEKAATLRTATAEGWVRLPPEARAALEGGTSPKGDP
CCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHEEECCCCEEECCCHHHHHHCCCCCCCCCC
LTVARLGGLAGSKRTADLVLLCHPIPVTGADVRVTLEKAGVRIVATVRTTAPTGVEMEAL
EEEEECCCCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCHHHH
TAVSVAALNVYDMLKAASKAIEITGVRLLSKTGGKSGDYTAPDT
HHHHHHHHHHHHHHHHHHHEEEEHEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SPEQDTSPELTHFRDGLPRMVDVTEKAATLRTATAEGWVRLPPEARAALEGGTSPKGDP
CCCCCCCCCHHHHHCCCCHHHHHHHHHHHHEEECCCCEEECCCHHHHHHCCCCCCCCCC
LTVARLGGLAGSKRTADLVLLCHPIPVTGADVRVTLEKAGVRIVATVRTTAPTGVEMEAL
EEEEECCCCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCHHHH
TAVSVAALNVYDMLKAASKAIEITGVRLLSKTGGKSGDYTAPDT
HHHHHHHHHHHHHHHHHHHEEEEHEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA