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The map label for this gene is desR [H]

Identifier: 94984291

GI number: 94984291

Start: 171911

End: 172513

Strand: Reverse

Name: desR [H]

Synonym: Dgeo_0183

Alternate gene names: 94984291

Gene position: 172513-171911 (Counterclockwise)

Preceding gene: 94984292

Following gene: 94984290

Centisome position: 6.99

GC content: 70.81

Gene sequence:

>603_bases
ATGATTCGTGTTCTGCTGGCTGAGGATCAGGCGCTGGTCCTGGGCGCGCTCTCGGCGCTGCTGTCCTTGGAAGGTGACCT
GGAGGTGGTGGGCACCGCAACAGACGGCGAAGCGGCCCTCGCGCTGGCGTGTGAGCTGCGCCCCGACGTGCTGGTCACCG
ATATCGAGATGCCGCGCCTGAGCGGGCTGGACCTGGCCGAGCGGCTGCGCACCCGCTGTCCGGAGGTCCGGGTGGTGATC
GTGACGACCTTTGCCCGGGCCGGATACCTGCGCCGCGCGCTGGAGGTGGGCGCACGTGGCTACCTCCTCAAGGACGCGCC
CGCATCCGATCTCGCCGGTGCCATTCGACAGGTCCACGCGGGCGGGCGGGCCATTGACCCTGGGTTGGCCGCCGAGGCGT
GGGGCGAGCGCGATCCCCTCACCGAGCGCGAGCGGCAGGTGCTGCGCGCGGCGGAGGGGGGAGCGAGCACCGCCGTCATC
GCAGCCCGGCTGAACCTCTCGGAAGGCACCGTCCGCAACTATCTCTCGGAAGCCATCAGCAAGCTGGGCTGCGAGAACCG
CATCGAGGCGGCCCGCAAGGCGCGCGAGCAAGGCTGGCTCTGA

Upstream 100 bases:

>100_bases
GCTTTGTGGGCACGCAGGGGGGGAGTGTTTCTGGCCCTCTGCCCTCTCCTGCAGAACTTGCCAGTTCGGCCCTCTCCACC
CTGCCGCGCCGGAGGCCCCA

Downstream 100 bases:

>100_bases
TGCAGCCCACCCCCCCTTCTGCTAGGCTGCGCCGCATGCGGTTGGTGGTGGGTGTAAGCGGCGGAAGCGGCATTCCCTAC
GCGCTGTCGGTGCTGCGGGC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MIRVLLAEDQALVLGALSALLSLEGDLEVVGTATDGEAALALACELRPDVLVTDIEMPRLSGLDLAERLRTRCPEVRVVI
VTTFARAGYLRRALEVGARGYLLKDAPASDLAGAIRQVHAGGRAIDPGLAAEAWGERDPLTERERQVLRAAEGGASTAVI
AARLNLSEGTVRNYLSEAISKLGCENRIEAARKAREQGWL

Sequences:

>Translated_200_residues
MIRVLLAEDQALVLGALSALLSLEGDLEVVGTATDGEAALALACELRPDVLVTDIEMPRLSGLDLAERLRTRCPEVRVVI
VTTFARAGYLRRALEVGARGYLLKDAPASDLAGAIRQVHAGGRAIDPGLAAEAWGERDPLTERERQVLRAAEGGASTAVI
AARLNLSEGTVRNYLSEAISKLGCENRIEAARKAREQGWL
>Mature_200_residues
MIRVLLAEDQALVLGALSALLSLEGDLEVVGTATDGEAALALACELRPDVLVTDIEMPRLSGLDLAERLRTRCPEVRVVI
VTTFARAGYLRRALEVGARGYLLKDAPASDLAGAIRQVHAGGRAIDPGLAAEAWGERDPLTERERQVLRAAEGGASTAVI
AARLNLSEGTVRNYLSEAISKLGCENRIEAARKAREQGWL

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=36.318407960199, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787473, Length=199, Percent_Identity=35.1758793969849, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=29.8076923076923, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1788521, Length=198, Percent_Identity=33.8383838383838, Blast_Score=87, Evalue=5e-19,
Organism=Escherichia coli, GI1788712, Length=191, Percent_Identity=25.130890052356, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082052, Length=104, Percent_Identity=39.4230769230769, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788192, Length=105, Percent_Identity=39.0476190476191, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1788546, Length=198, Percent_Identity=26.7676767676768, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21365; Mature: 21365

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVLLAEDQALVLGALSALLSLEGDLEVVGTATDGEAALALACELRPDVLVTDIEMPRL
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCEEEEECCCCCC
SGLDLAERLRTRCPEVRVVIVTTFARAGYLRRALEVGARGYLLKDAPASDLAGAIRQVHA
CCCCHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHC
GGRAIDPGLAAEAWGERDPLTERERQVLRAAEGGASTAVIAARLNLSEGTVRNYLSEAIS
CCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHH
KLGCENRIEAARKAREQGWL
HCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIRVLLAEDQALVLGALSALLSLEGDLEVVGTATDGEAALALACELRPDVLVTDIEMPRL
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCEEEEECCCCCC
SGLDLAERLRTRCPEVRVVIVTTFARAGYLRRALEVGARGYLLKDAPASDLAGAIRQVHA
CCCCHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHC
GGRAIDPGLAAEAWGERDPLTERERQVLRAAEGGASTAVIAARLNLSEGTVRNYLSEAIS
CCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHH
KLGCENRIEAARKAREQGWL
HCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]