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The map label for this gene is yycG [H]

Identifier: 94984237

GI number: 94984237

Start: 118468

End: 119442

Strand: Reverse

Name: yycG [H]

Synonym: Dgeo_0129

Alternate gene names: 94984237

Gene position: 119442-118468 (Counterclockwise)

Preceding gene: 94984238

Following gene: 94984236

Centisome position: 4.84

GC content: 67.59

Gene sequence:

>975_bases
ATGCCTGAGGTGCTCTCTCCCCGCAAAGACGCCTGGCTGGACACGTTGCCACAGGCGGTGCTGCTGTTCGAGGTGGGACA
GGACGCGCTGACCGTGACCCGAGTGAACGCCGCCGCCGTGCGGCTGTGGGGCGTGCCCCAAGAACGGGCGGCAGGACGGC
CTCTGCTGGAAATCGTGCGCCGCCACACCCTGGAAGCCCTGGCGGAGCGCGGTGGGGAACTGGAACTGGAGCTGGGCGGG
CGTACGCTGCGCTGCACCGCCACCTGCGCCGCCCCCGAACAGGACGGAGCGCTGATTGTAGAGGACATCACCGCCTGGCG
CCGCCGCGAGGCCGAACTGCGCGAAGCGACGGCGGTCCTCTCGCACGAGTTCCGCACGCCCGTCACCGGACTGCGTGGGG
TGCTGGAGGCGCTGGAATACGATATGCCGCCCGATCTCGCCCAGAATTTTGTGCGCCAGGGCTTGCAGGAGGTCGAACGC
CTTGCTCGGCTGGTCGAGGATCTCGCAGTCGGGTTTCGCCCCACCCGTGCCCGCACGCTGCCCCTCGCCGAAGCATTTGT
GCGCGCACAGCGGCTGCTGGCGCCGGAACTGGCCGCACGGCAGACCACCTTGACGTTTGGCGCCGATCATCTGGTGCGGG
CCGACCCGGACAAGCTGCTGCAAGTTCTGCTGAACCTGATCGAAAATGCGCTGAAGTATGGCCCACCCGGCCAGCCGATC
GAGGTGCAGACCCTCCCGCGCGGCTCCTGGATCGAAGTGGCGGTCTTGGACCACGGCGCGCCGCTGTCGGAGACAGAAAG
CCTCTTTCTGGCCCACACGCGTGGCCGCGGTGCTCCCGGGCAGGGCAGCGGCATGGGCCTCTATATCGTCCGCAGCATCG
TGCATGGTTGGGGTGGGCAGGCGTGGGCAGAACGGCGAGATGACCGAAATGCGTTTTGCTTTACGCTGCCGGGCGGAACA
GGAAACAGCCTATAG

Upstream 100 bases:

>100_bases
AACTGCGCGCGCATCTGGGAGACGATCCAGCTCGGCCCCGCTTTCTGGAAACGGTGCGCGGCAAGGGATACCGAATGCGG
CCCTGGGAGGGGGAGAACTG

Downstream 100 bases:

>100_bases
CGTGCCCGTGATGCTCGGCCAGCACCCCCACACTCCCCCCGCTTTACCCCAAGGAGTTCCCATGCGCAATGCCCTTGAAA
CCGATCTGCGAACTGTTCTG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MPEVLSPRKDAWLDTLPQAVLLFEVGQDALTVTRVNAAAVRLWGVPQERAAGRPLLEIVRRHTLEALAERGGELELELGG
RTLRCTATCAAPEQDGALIVEDITAWRRREAELREATAVLSHEFRTPVTGLRGVLEALEYDMPPDLAQNFVRQGLQEVER
LARLVEDLAVGFRPTRARTLPLAEAFVRAQRLLAPELAARQTTLTFGADHLVRADPDKLLQVLLNLIENALKYGPPGQPI
EVQTLPRGSWIEVAVLDHGAPLSETESLFLAHTRGRGAPGQGSGMGLYIVRSIVHGWGGQAWAERRDDRNAFCFTLPGGT
GNSL

Sequences:

>Translated_324_residues
MPEVLSPRKDAWLDTLPQAVLLFEVGQDALTVTRVNAAAVRLWGVPQERAAGRPLLEIVRRHTLEALAERGGELELELGG
RTLRCTATCAAPEQDGALIVEDITAWRRREAELREATAVLSHEFRTPVTGLRGVLEALEYDMPPDLAQNFVRQGLQEVER
LARLVEDLAVGFRPTRARTLPLAEAFVRAQRLLAPELAARQTTLTFGADHLVRADPDKLLQVLLNLIENALKYGPPGQPI
EVQTLPRGSWIEVAVLDHGAPLSETESLFLAHTRGRGAPGQGSGMGLYIVRSIVHGWGGQAWAERRDDRNAFCFTLPGGT
GNSL
>Mature_323_residues
PEVLSPRKDAWLDTLPQAVLLFEVGQDALTVTRVNAAAVRLWGVPQERAAGRPLLEIVRRHTLEALAERGGELELELGGR
TLRCTATCAAPEQDGALIVEDITAWRRREAELREATAVLSHEFRTPVTGLRGVLEALEYDMPPDLAQNFVRQGLQEVERL
ARLVEDLAVGFRPTRARTLPLAEAFVRAQRLLAPELAARQTTLTFGADHLVRADPDKLLQVLLNLIENALKYGPPGQPIE
VQTLPRGSWIEVAVLDHGAPLSETESLFLAHTRGRGAPGQGSGMGLYIVRSIVHGWGGQAWAERRDDRNAFCFTLPGGTG
NSL

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788279, Length=207, Percent_Identity=27.0531400966184, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786783, Length=215, Percent_Identity=29.3023255813954, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788393, Length=252, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=31.2217194570136, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790300, Length=349, Percent_Identity=25.214899713467, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786600, Length=300, Percent_Identity=27, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 35511; Mature: 35380

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEVLSPRKDAWLDTLPQAVLLFEVGQDALTVTRVNAAAVRLWGVPQERAAGRPLLEIVR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHEEEEECCCHHHHCCCHHHHHHH
RHTLEALAERGGELELELGGRTLRCTATCAAPEQDGALIVEDITAWRRREAELREATAVL
HHHHHHHHHCCCEEEEEECCEEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
SHEFRTPVTGLRGVLEALEYDMPPDLAQNFVRQGLQEVERLARLVEDLAVGFRPTRARTL
HHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PLAEAFVRAQRLLAPELAARQTTLTFGADHLVRADPDKLLQVLLNLIENALKYGPPGQPI
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
EVQTLPRGSWIEVAVLDHGAPLSETESLFLAHTRGRGAPGQGSGMGLYIVRSIVHGWGGQ
EEEECCCCCEEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCH
AWAERRDDRNAFCFTLPGGTGNSL
HHHHHCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
PEVLSPRKDAWLDTLPQAVLLFEVGQDALTVTRVNAAAVRLWGVPQERAAGRPLLEIVR
CCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHEEEEECCCHHHHCCCHHHHHHH
RHTLEALAERGGELELELGGRTLRCTATCAAPEQDGALIVEDITAWRRREAELREATAVL
HHHHHHHHHCCCEEEEEECCEEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
SHEFRTPVTGLRGVLEALEYDMPPDLAQNFVRQGLQEVERLARLVEDLAVGFRPTRARTL
HHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PLAEAFVRAQRLLAPELAARQTTLTFGADHLVRADPDKLLQVLLNLIENALKYGPPGQPI
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
EVQTLPRGSWIEVAVLDHGAPLSETESLFLAHTRGRGAPGQGSGMGLYIVRSIVHGWGGQ
EEEECCCCCEEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCH
AWAERRDDRNAFCFTLPGGTGNSL
HHHHHCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]