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The map label for this gene is regX3 [H]

Identifier: 94984238

GI number: 94984238

Start: 119442

End: 120131

Strand: Reverse

Name: regX3 [H]

Synonym: Dgeo_0130

Alternate gene names: 94984238

Gene position: 120131-119442 (Counterclockwise)

Preceding gene: 94984239

Following gene: 94984237

Centisome position: 4.87

GC content: 70.72

Gene sequence:

>690_bases
ATGAGCCACGTGGTCGTCATCGAGGACGAGAGCACCGTGCGGGAGGTGCTGCGCTTTCATCTGGAGCGGGCCGGGCTGCG
GGTGAGCGCGCTGGAATCGGTGCAGGGCGCCCAGGAGACGCTGCGGGGCGCCGACGCGCTGGTGCTGGACTGGATGCTGC
CGGGCGAGAGCGGCCTCGCGTATCTGCGCCGGCTGCGCGGGGATCCGGAGCTGCGCCGCCTGCCCGTGCTGATGCTTACT
GCTCGCGCGGCGGAGGCCGAGCGCGTGGAGGGCCTCGAAAGCGGCGCCGACGACTACCTCACCAAGCCCTTCAGCGCGGC
GGAACTGGTCGCCCGCGTGCGGGCCTTGCTGCGCCGTGCCCAGCCTGACACGCCGCAACAGCTCAGCCACGGTCCCCTCA
GCATGGACCTGGGCGCGGCCGAGGCGCGGCTGGCTGGCATTCGGCTGCACCTCACTCGGCGCGAATTCGACCTGCTGGCC
TTTCTGACCCAGAACGCCGGGCGGGTGTACACGCGCACCGAACTGCTCGACCGAGTGTGGGGCGCGGATTTCCTGGGCGG
CGAGCGCACCGTGGACCAGCATGTCACGCAACTGCGCGCGCATCTGGGAGACGATCCAGCTCGGCCCCGCTTTCTGGAAA
CGGTGCGCGGCAAGGGATACCGAATGCGGCCCTGGGAGGGGGAGAACTGA

Upstream 100 bases:

>100_bases
GACGCCAAACCAAACGGTGTAGCGGGCACCGGAGGGAGACGGTGAAGGGGGAAGCGCTGTCCTGACATTCCCCTGACTGC
CCGTCGCAGAATAAACCTCA

Downstream 100 bases:

>100_bases
TGCCTGAGGTGCTCTCTCCCCGCAAAGACGCCTGGCTGGACACGTTGCCACAGGCGGTGCTGCTGTTCGAGGTGGGACAG
GACGCGCTGACCGTGACCCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSHVVVIEDESTVREVLRFHLERAGLRVSALESVQGAQETLRGADALVLDWMLPGESGLAYLRRLRGDPELRRLPVLMLT
ARAAEAERVEGLESGADDYLTKPFSAAELVARVRALLRRAQPDTPQQLSHGPLSMDLGAAEARLAGIRLHLTRREFDLLA
FLTQNAGRVYTRTELLDRVWGADFLGGERTVDQHVTQLRAHLGDDPARPRFLETVRGKGYRMRPWEGEN

Sequences:

>Translated_229_residues
MSHVVVIEDESTVREVLRFHLERAGLRVSALESVQGAQETLRGADALVLDWMLPGESGLAYLRRLRGDPELRRLPVLMLT
ARAAEAERVEGLESGADDYLTKPFSAAELVARVRALLRRAQPDTPQQLSHGPLSMDLGAAEARLAGIRLHLTRREFDLLA
FLTQNAGRVYTRTELLDRVWGADFLGGERTVDQHVTQLRAHLGDDPARPRFLETVRGKGYRMRPWEGEN
>Mature_228_residues
SHVVVIEDESTVREVLRFHLERAGLRVSALESVQGAQETLRGADALVLDWMLPGESGLAYLRRLRGDPELRRLPVLMLTA
RAAEAERVEGLESGADDYLTKPFSAAELVARVRALLRRAQPDTPQQLSHGPLSMDLGAAEARLAGIRLHLTRREFDLLAF
LTQNAGRVYTRTELLDRVWGADFLGGERTVDQHVTQLRAHLGDDPARPRFLETVRGKGYRMRPWEGEN

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=40.990990990991, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=38.9380530973451, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=34.6320346320346, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=40.2714932126697, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=35.3711790393013, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=37.280701754386, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=38.8127853881278, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=37.6623376623377, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=39.1111111111111, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=34.841628959276, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=32.1888412017167, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=33.1896551724138, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI145693140, Length=242, Percent_Identity=30.5785123966942, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=30.8943089430894, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790299, Length=143, Percent_Identity=34.2657342657343, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25682; Mature: 25550

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHVVVIEDESTVREVLRFHLERAGLRVSALESVQGAQETLRGADALVLDWMLPGESGLA
CCCEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHH
YLRRLRGDPELRRLPVLMLTARAAEAERVEGLESGADDYLTKPFSAAELVARVRALLRRA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHC
QPDTPQQLSHGPLSMDLGAAEARLAGIRLHLTRREFDLLAFLTQNAGRVYTRTELLDRVW
CCCCHHHHCCCCCCCCCCHHHHHHHHEEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GADFLGGERTVDQHVTQLRAHLGDDPARPRFLETVRGKGYRMRPWEGEN
CCHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEECCCCCCCC
>Mature Secondary Structure 
SHVVVIEDESTVREVLRFHLERAGLRVSALESVQGAQETLRGADALVLDWMLPGESGLA
CCEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHH
YLRRLRGDPELRRLPVLMLTARAAEAERVEGLESGADDYLTKPFSAAELVARVRALLRRA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHC
QPDTPQQLSHGPLSMDLGAAEARLAGIRLHLTRREFDLLAFLTQNAGRVYTRTELLDRVW
CCCCHHHHCCCCCCCCCCHHHHHHHHEEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GADFLGGERTVDQHVTQLRAHLGDDPARPRFLETVRGKGYRMRPWEGEN
CCHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA