Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 94984217

GI number: 94984217

Start: 102407

End: 103123

Strand: Reverse

Name: fabG [H]

Synonym: Dgeo_0109

Alternate gene names: 94984217

Gene position: 103123-102407 (Counterclockwise)

Preceding gene: 94984218

Following gene: 94984215

Centisome position: 4.18

GC content: 70.29

Gene sequence:

>717_bases
ATGAGGGGCACCGCCCTGGTCACCGGCGCGGCGCGCGGGATCGGGCGGGCCCTCGCGCTGGCCCTGGCCGCCGAAGGGTA
CGCCCTCGCCGTGCATTACCGGGGCAGCGCGGCGGACGCGCGGGAGACGGCCCGGTTGTGTGAGGAAAAGGGTGTCCCGG
CCACCACCCTGCAGGCCGACGTGACGGACCCCGCGCAGGCGCGGCGGCTGGTGCGGGAGGCCCACACCGCCTTTCCCCCT
TTGCCCCTCGCCGTCTTGGTGAACAACGTGGGCAACTATGTCCACCGGCCTCTGCTCGAGACCACCGACGCCGAATGGGC
CGACATGCTCGCCAGCAACCTGACCGCCACCTTCGCGACCTGTCAAGCGGCCGCGCCGCTGATGCAGGCGGCGGGCTTCG
GGCGGATCGTGAATCTGGGGTACGCGGGGGCGCGCCACCTCGTCGCCCGACCGGGCATCGTCCCCTATGTGATTGCCAAG
GCGGGCGTCTTGCAGCTCTCGCAGGCACTCGGCAAGGTGCTGGCGGGCAGCGGCGTCAGCGTGAATGTGGTCAGCCCCGG
CGTGATCGAAACCAGCGTCAGCCAGCCCCTGCGCGAGATTCCCGCCGGACGGGCCGGCACTGTGGCTGAACTCGTGGATG
CTGCCCTCTATTTCGTTCGTGCGAGCGACTACATCACGGGTCAGGAACTGGAGGTGGCCGGCGGCTGGAATCTTTGA

Upstream 100 bases:

>100_bases
TCGAGGCATGGGTCTGGGTGCCGCTGGCGGAGGCGGCAGGCTATCCGCTGAATACCGTCACCCGCATGCTGGTCGAACTG
GCCCAGACGTGGGAGGAAGC

Downstream 100 bases:

>100_bases
CTGGAATCTTTGAGAGGGGTGAGGGGCAGGAACAGTCTTTTTTCCCTTTCTTCCTCACTTCTTAGCCCGCTCACCTTACC
GGCACCACCCGCAAGTCCAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRGTALVTGAARGIGRALALALAAEGYALAVHYRGSAADARETARLCEEKGVPATTLQADVTDPAQARRLVREAHTAFPP
LPLAVLVNNVGNYVHRPLLETTDAEWADMLASNLTATFATCQAAAPLMQAAGFGRIVNLGYAGARHLVARPGIVPYVIAK
AGVLQLSQALGKVLAGSGVSVNVVSPGVIETSVSQPLREIPAGRAGTVAELVDAALYFVRASDYITGQELEVAGGWNL

Sequences:

>Translated_238_residues
MRGTALVTGAARGIGRALALALAAEGYALAVHYRGSAADARETARLCEEKGVPATTLQADVTDPAQARRLVREAHTAFPP
LPLAVLVNNVGNYVHRPLLETTDAEWADMLASNLTATFATCQAAAPLMQAAGFGRIVNLGYAGARHLVARPGIVPYVIAK
AGVLQLSQALGKVLAGSGVSVNVVSPGVIETSVSQPLREIPAGRAGTVAELVDAALYFVRASDYITGQELEVAGGWNL
>Mature_238_residues
MRGTALVTGAARGIGRALALALAAEGYALAVHYRGSAADARETARLCEEKGVPATTLQADVTDPAQARRLVREAHTAFPP
LPLAVLVNNVGNYVHRPLLETTDAEWADMLASNLTATFATCQAAAPLMQAAGFGRIVNLGYAGARHLVARPGIVPYVIAK
AGVLQLSQALGKVLAGSGVSVNVVSPGVIETSVSQPLREIPAGRAGTVAELVDAALYFVRASDYITGQELEVAGGWNL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=34.136546184739, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=31.5789473684211, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=30.1158301158301, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI4504505, Length=238, Percent_Identity=27.7310924369748, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=29.5081967213115, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=34.5679012345679, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=34.5381526104418, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=33.8709677419355, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=30.1652892561983, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=29.3172690763052, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=30.3643724696356, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=28.4046692607004, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=27.34375, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=29.8387096774194, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=28.9156626506024, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=28.3400809716599, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=27.4193548387097, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=25.6603773584906, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=28.7878787878788, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=28.0898876404494, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=29.0076335877863, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=27.0588235294118, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=30.1526717557252, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=29.3233082706767, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=29.277566539924, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=29.277566539924, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=27.9693486590038, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=31.0204081632653, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=29.4354838709677, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=31.8725099601594, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=30.6451612903226, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=31.7269076305221, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18859837, Length=245, Percent_Identity=26.9387755102041, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24635; Mature: 24635

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGTALVTGAARGIGRALALALAAEGYALAVHYRGSAADARETARLCEEKGVPATTLQAD
CCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECC
VTDPAQARRLVREAHTAFPPLPLAVLVNNVGNYVHRPLLETTDAEWADMLASNLTATFAT
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
CQAAAPLMQAAGFGRIVNLGYAGARHLVARPGIVPYVIAKAGVLQLSQALGKVLAGSGVS
HHHHHHHHHHCCCCCEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
VNVVSPGVIETSVSQPLREIPAGRAGTVAELVDAALYFVRASDYITGQELEVAGGWNL
EEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MRGTALVTGAARGIGRALALALAAEGYALAVHYRGSAADARETARLCEEKGVPATTLQAD
CCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECC
VTDPAQARRLVREAHTAFPPLPLAVLVNNVGNYVHRPLLETTDAEWADMLASNLTATFAT
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
CQAAAPLMQAAGFGRIVNLGYAGARHLVARPGIVPYVIAKAGVLQLSQALGKVLAGSGVS
HHHHHHHHHHCCCCCEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
VNVVSPGVIETSVSQPLREIPAGRAGTVAELVDAALYFVRASDYITGQELEVAGGWNL
EEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA