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The map label for this gene is degP [H]

Identifier: 94984211

GI number: 94984211

Start: 96805

End: 97908

Strand: Reverse

Name: degP [H]

Synonym: Dgeo_0103

Alternate gene names: 94984211

Gene position: 97908-96805 (Counterclockwise)

Preceding gene: 94984212

Following gene: 94984210

Centisome position: 3.97

GC content: 66.21

Gene sequence:

>1104_bases
GTGAAGCCTGCCCTGCGCGCCGCCGGAATTCTGCTGTTGCTCGCCGGGGCGGTCACCGGGGCCTATGTCACCGGCCGCGT
CAGTGCGCAACGTGCCCTGGTGACCCCCGATGAGATCAACACTGTCGAGGTCACGCAAAAAGCCCTTCAGGCGGTCGTGC
GGGTAGACAACCGGCTCCGCAAGGACGTGCTGCAGCCGGGTGACGATCCCGTCGAGACGGGCAGCGGGTTCTTTTATAAG
CAGAACCTGATTGTCACCAACTACCACGTCATTCAGGACCAGGAGTCGGTGAGTGTCACCCTCTACAACGGGCGGCGAGT
GCCGGCGCGGGTGGAGGGCATTGACCCCGGCATCGACATCGCGATCCTGCGGGTGACCGGTGTCACGGCTCCCAAGACCC
TCAGCTTCGGGCGCAGCGCGGGTCTGATTCCAGGGCAGAAGCTGATCACGATCGGTACGCCCCTCAAGATCCAGAACTTC
GTGACGACCGGGGTCTTTAGTGTCTTGGCCAGCGCGCGCGACGTGCCGCGCAACGATCAGCTCGGGCAGGAGATCGGCCA
GTACCTGATCACCAGTGCCAACATTCAGCAGGGCAACAGCGGCGGACCCGTCCTCGATTCGCGCGGAGCGGTGGTCGGGG
TGGCCGACGCCAACGCGGCACCCAACAGCTTCGTGCCCGGTGTGATTGGCATTGCCATTCCCGGGGACCTGGTCCGCCAG
AGCCTCGACGACCTGGAAAAGATCGGCGTGCCCCAGCGCGGTACTCTGGGCGTGACGCTGGTGGACCTCGACAGCCTCGA
TCCGGCCCTGCGCCAGCTCGCGGGCCTCAGCAGCAGTGAGGGCGCCCTGGTGGATGAGGTGCCTGCCGGGACCGCCGGAG
CCAGAGCGGGCCTGCGCGGCTCCCTGCGCAACAGCCGCGGTCAGCTGCTCGCGCCGCTGGGCGACGTGATCGTATCGGTA
GACGGCCAGCGGGTTCGCAATTCCTTCGACGTGATTCGGCTGGTCGCCGCCAAGCGGCCGGGCCAAACCGTCACCCTGCG
GGTCTGGCGCAACAAGAAGCCTGTGGACGTGAAGGTGACCCTCCAGAAGCGCACCTTGCAATAA

Upstream 100 bases:

>100_bases
TCAAGCGTGTCCTTTCCACGCCCGGCATCGCTTTCCGGGGTAGCGGCTTCTACGTGACCGACTCGCGGCCCAAACCCGCG
GGCGAGGGCGGCGGCGGCGA

Downstream 100 bases:

>100_bases
GGCCATCAACGAGTCGCTCTCCACACAATGTGCTCTGGCCCCTGCCAGAGCATGTTTTTTGAACGGCCAACCGCCGATCA
ACGAAAGCTCTATCATCTGG

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: Antigen htrA [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKPALRAAGILLLLAGAVTGAYVTGRVSAQRALVTPDEINTVEVTQKALQAVVRVDNRLRKDVLQPGDDPVETGSGFFYK
QNLIVTNYHVIQDQESVSVTLYNGRRVPARVEGIDPGIDIAILRVTGVTAPKTLSFGRSAGLIPGQKLITIGTPLKIQNF
VTTGVFSVLASARDVPRNDQLGQEIGQYLITSANIQQGNSGGPVLDSRGAVVGVADANAAPNSFVPGVIGIAIPGDLVRQ
SLDDLEKIGVPQRGTLGVTLVDLDSLDPALRQLAGLSSSEGALVDEVPAGTAGARAGLRGSLRNSRGQLLAPLGDVIVSV
DGQRVRNSFDVIRLVAAKRPGQTVTLRVWRNKKPVDVKVTLQKRTLQ

Sequences:

>Translated_367_residues
MKPALRAAGILLLLAGAVTGAYVTGRVSAQRALVTPDEINTVEVTQKALQAVVRVDNRLRKDVLQPGDDPVETGSGFFYK
QNLIVTNYHVIQDQESVSVTLYNGRRVPARVEGIDPGIDIAILRVTGVTAPKTLSFGRSAGLIPGQKLITIGTPLKIQNF
VTTGVFSVLASARDVPRNDQLGQEIGQYLITSANIQQGNSGGPVLDSRGAVVGVADANAAPNSFVPGVIGIAIPGDLVRQ
SLDDLEKIGVPQRGTLGVTLVDLDSLDPALRQLAGLSSSEGALVDEVPAGTAGARAGLRGSLRNSRGQLLAPLGDVIVSV
DGQRVRNSFDVIRLVAAKRPGQTVTLRVWRNKKPVDVKVTLQKRTLQ
>Mature_367_residues
MKPALRAAGILLLLAGAVTGAYVTGRVSAQRALVTPDEINTVEVTQKALQAVVRVDNRLRKDVLQPGDDPVETGSGFFYK
QNLIVTNYHVIQDQESVSVTLYNGRRVPARVEGIDPGIDIAILRVTGVTAPKTLSFGRSAGLIPGQKLITIGTPLKIQNF
VTTGVFSVLASARDVPRNDQLGQEIGQYLITSANIQQGNSGGPVLDSRGAVVGVADANAAPNSFVPGVIGIAIPGDLVRQ
SLDDLEKIGVPQRGTLGVTLVDLDSLDPALRQLAGLSSSEGALVDEVPAGTAGARAGLRGSLRNSRGQLLAPLGDVIVSV
DGQRVRNSFDVIRLVAAKRPGQTVTLRVWRNKKPVDVKVTLQKRTLQ

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI7019477, Length=328, Percent_Identity=32.6219512195122, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI4506141, Length=307, Percent_Identity=30.9446254071661, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI24308541, Length=282, Percent_Identity=30.8510638297872, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI22129776, Length=322, Percent_Identity=29.1925465838509, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1789629, Length=300, Percent_Identity=30, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1786356, Length=283, Percent_Identity=28.9752650176678, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789630, Length=323, Percent_Identity=28.1733746130031, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24646839, Length=310, Percent_Identity=30.6451612903226, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 38714; Mature: 38714

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPALRAAGILLLLAGAVTGAYVTGRVSAQRALVTPDEINTVEVTQKALQAVVRVDNRLR
CCCHHHHHHHHHHHHHHHHCCEEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
KDVLQPGDDPVETGSGFFYKQNLIVTNYHVIQDQESVSVTLYNGRRVPARVEGIDPGIDI
HHHHCCCCCCCCCCCCEEEECCEEEEEEEEEECCCCEEEEEECCCCCCEEECCCCCCCCE
AILRVTGVTAPKTLSFGRSAGLIPGQKLITIGTPLKIQNFVTTGVFSVLASARDVPRNDQ
EEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCHH
LGQEIGQYLITSANIQQGNSGGPVLDSRGAVVGVADANAAPNSFVPGVIGIAIPGDLVRQ
HHHHHHHHHEECCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCCCCEEEEECCHHHHHH
SLDDLEKIGVPQRGTLGVTLVDLDSLDPALRQLAGLSSSEGALVDEVPAGTAGARAGLRG
HHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCC
SLRNSRGQLLAPLGDVIVSVDGQRVRNSFDVIRLVAAKRPGQTVTLRVWRNKKPVDVKVT
CCCCCCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEE
LQKRTLQ
EECCCCC
>Mature Secondary Structure
MKPALRAAGILLLLAGAVTGAYVTGRVSAQRALVTPDEINTVEVTQKALQAVVRVDNRLR
CCCHHHHHHHHHHHHHHHHCCEEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
KDVLQPGDDPVETGSGFFYKQNLIVTNYHVIQDQESVSVTLYNGRRVPARVEGIDPGIDI
HHHHCCCCCCCCCCCCEEEECCEEEEEEEEEECCCCEEEEEECCCCCCEEECCCCCCCCE
AILRVTGVTAPKTLSFGRSAGLIPGQKLITIGTPLKIQNFVTTGVFSVLASARDVPRNDQ
EEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCHH
LGQEIGQYLITSANIQQGNSGGPVLDSRGAVVGVADANAAPNSFVPGVIGIAIPGDLVRQ
HHHHHHHHHEECCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCCCCEEEEECCHHHHHH
SLDDLEKIGVPQRGTLGVTLVDLDSLDPALRQLAGLSSSEGALVDEVPAGTAGARAGLRG
HHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCC
SLRNSRGQLLAPLGDVIVSVDGQRVRNSFDVIRLVAAKRPGQTVTLRVWRNKKPVDVKVT
CCCCCCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEE
LQKRTLQ
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8027347 [H]