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The map label for this gene is dgk [H]

Identifier: 94984210

GI number: 94984210

Start: 96083

End: 96700

Strand: Reverse

Name: dgk [H]

Synonym: Dgeo_0102

Alternate gene names: 94984210

Gene position: 96700-96083 (Counterclockwise)

Preceding gene: 94984211

Following gene: 94984209

Centisome position: 3.92

GC content: 62.78

Gene sequence:

>618_bases
ATGTACCTGGTCGTCGAAGGCCCCATCGGGGTAGGAAAAACGAGCCTGGCGGGGCGGCTTGCGGCGCGCTACGGCGCGGC
ACTGAACCTGGAGGTCGTGGAGGAGAATCCCTTCCTGGCCCGCTTTTACGAGGCGCCGGAGACGTACGCTTTTCAAGTCC
AGGTGTTTTTTCTGCTGTCACGCTTCAAGCAGCTTTCAAAGCTTGCGCAGCCGGGGCTGTGGAGCGGGAACGTCGTGAGT
GACTATCTCTTCGACAAGGACTTCATCTTTGCCGCGATGAACCTCAAAGACGCCGAGTTCGCCCTGTATGAAGACCTCTA
CGCGCATCTCTCGCCTCGGCTGCCCACGCCCGACCTGGTGATCTATCTGCGCGCCGAGCCGGAACTCCTCCTCGCGCGGA
TCGAACAACGCGGGCGCCCCTTCGAGCGCGCCATGCAGGCAGACTACCTGCGTGAGCTGACCGCCCGTTACGACGCATAC
TTCCGCACCTATCCGGGCCACGTTCTGACGGTGGACGCCAGCCACTACGACTTTGTGTGCCGCCCAGACGACGAACAGGC
GCTCCTGGCCCACATCGCTGCGGCCCTACCCACCCGAACAGAGGAAGGTACGGCCTGA

Upstream 100 bases:

>100_bases
ATCAACGAGTCGCTCTCCACACAATGTGCTCTGGCCCCTGCCAGAGCATGTTTTTTGAACGGCCAACCGCCGATCAACGA
AAGCTCTATCATCTGGCGTC

Downstream 100 bases:

>100_bases
TGAGGCATGCGGCACAGGGCGTGAGGAGCGAGAAAACCAGCTTCTCCCCAGGGAGGCCCTGATGTACCTCGCCCTCTCCG
GCAACATCGGCAGCGGCAAG

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MYLVVEGPIGVGKTSLAGRLAARYGAALNLEVVEENPFLARFYEAPETYAFQVQVFFLLSRFKQLSKLAQPGLWSGNVVS
DYLFDKDFIFAAMNLKDAEFALYEDLYAHLSPRLPTPDLVIYLRAEPELLLARIEQRGRPFERAMQADYLRELTARYDAY
FRTYPGHVLTVDASHYDFVCRPDDEQALLAHIAAALPTRTEEGTA

Sequences:

>Translated_205_residues
MYLVVEGPIGVGKTSLAGRLAARYGAALNLEVVEENPFLARFYEAPETYAFQVQVFFLLSRFKQLSKLAQPGLWSGNVVS
DYLFDKDFIFAAMNLKDAEFALYEDLYAHLSPRLPTPDLVIYLRAEPELLLARIEQRGRPFERAMQADYLRELTARYDAY
FRTYPGHVLTVDASHYDFVCRPDDEQALLAHIAAALPTRTEEGTA
>Mature_205_residues
MYLVVEGPIGVGKTSLAGRLAARYGAALNLEVVEENPFLARFYEAPETYAFQVQVFFLLSRFKQLSKLAQPGLWSGNVVS
DYLFDKDFIFAAMNLKDAEFALYEDLYAHLSPRLPTPDLVIYLRAEPELLLARIEQRGRPFERAMQADYLRELTARYDAY
FRTYPGHVLTVDASHYDFVCRPDDEQALLAHIAAALPTRTEEGTA

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 23266; Mature: 23266

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLVVEGPIGVGKTSLAGRLAARYGAALNLEVVEENPFLARFYEAPETYAFQVQVFFLLS
CEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCEEEEECCCCCEEEHHHHHHHHH
RFKQLSKLAQPGLWSGNVVSDYLFDKDFIFAAMNLKDAEFALYEDLYAHLSPRLPTPDLV
HHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEE
IYLRAEPELLLARIEQRGRPFERAMQADYLRELTARYDAYFRTYPGHVLTVDASHYDFVC
EEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCEEEE
RPDDEQALLAHIAAALPTRTEEGTA
CCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MYLVVEGPIGVGKTSLAGRLAARYGAALNLEVVEENPFLARFYEAPETYAFQVQVFFLLS
CEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCEEEEECCCCCEEEHHHHHHHHH
RFKQLSKLAQPGLWSGNVVSDYLFDKDFIFAAMNLKDAEFALYEDLYAHLSPRLPTPDLV
HHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEE
IYLRAEPELLLARIEQRGRPFERAMQADYLRELTARYDAYFRTYPGHVLTVDASHYDFVC
EEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCEEEE
RPDDEQALLAHIAAALPTRTEEGTA
CCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]