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The map label for this gene is ackA

Identifier: 94984160

GI number: 94984160

Start: 48809

End: 49996

Strand: Reverse

Name: ackA

Synonym: Dgeo_0052

Alternate gene names: 94984160

Gene position: 49996-48809 (Counterclockwise)

Preceding gene: 94984161

Following gene: 94984159

Centisome position: 2.03

GC content: 69.44

Gene sequence:

>1188_bases
ATGTGGACGCTGGTGGTGAATTGCGGGTCGAGCAGTCTCAAATTCGCGCTGCTGAATCCCGCCACGGGAGAGACGCCGCT
GACCGGCCTCGCGGAGCGGCTGGGGTCCGACCTGGCCGCGGTGCGGGTCGACCGGGGGGAGGAACGGGGGACCGTCCCGC
TGCCACAGGGCAGCTACTCGGAAGCCTTTGGTGTGCTGCTGGCCGAACTGGACGCGCTGGGACTGCGGCAGGAGGTCCGG
GCGGTCGGACACCGGGTTGTTCACGGCGGTGACCGCTTCAACGCGCCGGTACGGATCACGCCGGAGGTACTGGAGGTGAT
CCGTACCTGTATTCCCCTTGCGCCGCTGCACAACCCGGCGAACCTGGCGGGGATCGAGGCGGCGCTGGCCGCTTTTCCGG
AGCTGCCGCAGGTCGCGGTCTTCGACACCGCCTTTCACCAGAGCATGCCCCCCGTCGCCTACCGCTACGCAGTCCCGACT
GTCTGGTATACCTGCTACGGCGTGCGGCGCTACGGCTTTCATGGCATCAGCCATGCCTATGTGGCCGAGGAGGCCGCGCG
GCTCCTAGCGCGCGACCTCACAGACCTGAGCCTGGTGACGGCACACCTGGGCAATGGCTGCAGCGTGACCGCCGTGCAAG
GCGGGCGCAGCCTGGACACCAGCATGGGCCTCACGCCGCTCGAAGGGTTGGTGATGGGCACCCGCAGCGGCGACGTGGAC
CCTGGCCTGCCCGACTACCTCGCGCGAGAAGCGGGCCTGACCCTCGCCGAAATCACGGCGGCCCTCAACCGGGAAAGCGG
GCTGCTGGGCCTGTCGGGTCTCACGAACGACATGCGCGAGCTGGAGGCAGCGGCGGCGGGGGGCAACACCAATGCCCAGC
TGGCGCTGGAGATCTTTGTATACCGCCTTGCCAAGACGATCGCGGGCATGGCGACTGTGCTCGGGCGGCTGGACGCGCTG
GTCTTTACGGGCGGCATTGGGGAGAACAGCGCCACGGTGCGGGCCGCCACCCTCGCCCGGCTGGGGCTGCTGGGCTTCCA
GCTGGACGCGGCGGCCAACGCACAGGCGGTGCGTGGCCAGGGGGGCGTCATCACCTCCGGCGGCGTCCCCGCACTGGTCG
TGAACACGAACGAGGAACGCATGATCGCCCGTGAGACCGCGCGGGCGGTGAAAGGAGCGCCGGCATGA

Upstream 100 bases:

>100_bases
CCTGAGGTGCGGCGGATCACCCGGCGCCGCTGATGCGCAGTTGTCTTGAGCGGGGCGTTTACCCCCTGTCCTGACCCGCT
TGCTGGGCCAGAATGCAGCC

Downstream 100 bases:

>100_bases
AAACCCTCTTCATCGCCCCCACCCGCAACGGCGTGGGCCTGACCAGCACGGCGCTGGGACTGCTGCGCGCGCTGGAGCGC
CAAGGCCTCAAAGTCGCCTT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MWTLVVNCGSSSLKFALLNPATGETPLTGLAERLGSDLAAVRVDRGEERGTVPLPQGSYSEAFGVLLAELDALGLRQEVR
AVGHRVVHGGDRFNAPVRITPEVLEVIRTCIPLAPLHNPANLAGIEAALAAFPELPQVAVFDTAFHQSMPPVAYRYAVPT
VWYTCYGVRRYGFHGISHAYVAEEAARLLARDLTDLSLVTAHLGNGCSVTAVQGGRSLDTSMGLTPLEGLVMGTRSGDVD
PGLPDYLAREAGLTLAEITAALNRESGLLGLSGLTNDMRELEAAAAGGNTNAQLALEIFVYRLAKTIAGMATVLGRLDAL
VFTGGIGENSATVRAATLARLGLLGFQLDAAANAQAVRGQGGVITSGGVPALVVNTNEERMIARETARAVKGAPA

Sequences:

>Translated_395_residues
MWTLVVNCGSSSLKFALLNPATGETPLTGLAERLGSDLAAVRVDRGEERGTVPLPQGSYSEAFGVLLAELDALGLRQEVR
AVGHRVVHGGDRFNAPVRITPEVLEVIRTCIPLAPLHNPANLAGIEAALAAFPELPQVAVFDTAFHQSMPPVAYRYAVPT
VWYTCYGVRRYGFHGISHAYVAEEAARLLARDLTDLSLVTAHLGNGCSVTAVQGGRSLDTSMGLTPLEGLVMGTRSGDVD
PGLPDYLAREAGLTLAEITAALNRESGLLGLSGLTNDMRELEAAAAGGNTNAQLALEIFVYRLAKTIAGMATVLGRLDAL
VFTGGIGENSATVRAATLARLGLLGFQLDAAANAQAVRGQGGVITSGGVPALVVNTNEERMIARETARAVKGAPA
>Mature_395_residues
MWTLVVNCGSSSLKFALLNPATGETPLTGLAERLGSDLAAVRVDRGEERGTVPLPQGSYSEAFGVLLAELDALGLRQEVR
AVGHRVVHGGDRFNAPVRITPEVLEVIRTCIPLAPLHNPANLAGIEAALAAFPELPQVAVFDTAFHQSMPPVAYRYAVPT
VWYTCYGVRRYGFHGISHAYVAEEAARLLARDLTDLSLVTAHLGNGCSVTAVQGGRSLDTSMGLTPLEGLVMGTRSGDVD
PGLPDYLAREAGLTLAEITAALNRESGLLGLSGLTNDMRELEAAAAGGNTNAQLALEIFVYRLAKTIAGMATVLGRLDAL
VFTGGIGENSATVRAATLARLGLLGFQLDAAANAQAVRGQGGVITSGGVPALVVNTNEERMIARETARAVKGAPA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=395, Percent_Identity=47.5949367088608, Blast_Score=352, Evalue=3e-98,
Organism=Escherichia coli, GI1788633, Length=392, Percent_Identity=46.6836734693878, Blast_Score=344, Evalue=6e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_DEIGD (Q1J2C9)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_603524.1
- ProteinModelPortal:   Q1J2C9
- SMR:   Q1J2C9
- STRING:   Q1J2C9
- GeneID:   4058493
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_0052
- NMPDR:   fig|68909.1.peg.1505
- eggNOG:   COG0282
- HOGENOM:   HBG285863
- OMA:   HGGDLFT
- PhylomeDB:   Q1J2C9
- ProtClustDB:   PRK00180
- BioCyc:   DGEO319795:DGEO_0052-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 41229; Mature: 41229

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWTLVVNCGSSSLKFALLNPATGETPLTGLAERLGSDLAAVRVDRGEERGTVPLPQGSYS
CEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHH
EAFGVLLAELDALGLRQEVRAVGHRVVHGGDRFNAPVRITPEVLEVIRTCIPLAPLHNPA
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEECHHHHHHHHHHCCCCCCCCCC
NLAGIEAALAAFPELPQVAVFDTAFHQSMPPVAYRYAVPTVWYTCYGVRRYGFHGISHAY
HHHHHHHHHHHCCCCCCEEEEHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHH
VAEEAARLLARDLTDLSLVTAHLGNGCSVTAVQGGRSLDTSMGLTPLEGLVMGTRSGDVD
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHEEEECCCCCCC
PGLPDYLAREAGLTLAEITAALNRESGLLGLSGLTNDMRELEAAAAGGNTNAQLALEIFV
CCCHHHHHHHHCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
YRLAKTIAGMATVLGRLDALVFTGGIGENSATVRAATLARLGLLGFQLDAAANAQAVRGQ
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCEECCC
GGVITSGGVPALVVNTNEERMIARETARAVKGAPA
CCEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MWTLVVNCGSSSLKFALLNPATGETPLTGLAERLGSDLAAVRVDRGEERGTVPLPQGSYS
CEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHH
EAFGVLLAELDALGLRQEVRAVGHRVVHGGDRFNAPVRITPEVLEVIRTCIPLAPLHNPA
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEECHHHHHHHHHHCCCCCCCCCC
NLAGIEAALAAFPELPQVAVFDTAFHQSMPPVAYRYAVPTVWYTCYGVRRYGFHGISHAY
HHHHHHHHHHHCCCCCCEEEEHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHH
VAEEAARLLARDLTDLSLVTAHLGNGCSVTAVQGGRSLDTSMGLTPLEGLVMGTRSGDVD
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHEEEECCCCCCC
PGLPDYLAREAGLTLAEITAALNRESGLLGLSGLTNDMRELEAAAAGGNTNAQLALEIFV
CCCHHHHHHHHCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
YRLAKTIAGMATVLGRLDALVFTGGIGENSATVRAATLARLGLLGFQLDAAANAQAVRGQ
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCEECCC
GGVITSGGVPALVVNTNEERMIARETARAVKGAPA
CCEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA