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The map label for this gene is atoD1 [H]

Identifier: 94994850

GI number: 94994850

Start: 1390300

End: 1390962

Strand: Direct

Name: atoD1 [H]

Synonym: MGAS10750_Spy1454

Alternate gene names: 94994850

Gene position: 1390300-1390962 (Clockwise)

Preceding gene: 94994849

Following gene: 94994851

Centisome position: 71.77

GC content: 41.03

Gene sequence:

>663_bases
TTGGTAGAAAAAATGTGTAAAGAAATCACAATAAAAGAAGCGGTAGCTCACGTTAAAGATGGTGATACCATTATGGTTGG
TGGCTTCATGACAAATGGCACACCAGAAAAATTAATTGATGCACTTGTGGAAAAAGGTGTCAAAGACCTCACTTTAATCT
GTAACGATGCCGGTTTTCCTGACAAAGGCGTTGGTAAGATGGTTGCCAATAAACAGTTTTCAACTATTATTGCATCACAT
ATCGGTCTCAACCGTGAAGCGGGCCGACAAATGACTGAGGGCGAGACTGTAATTGATCTTGTACCTCAGGGAACATTAGC
TGAGCGCATCCGCAGTGGCGGTTTTGGGCTAGGCGGTTTCTTAACACCTACTGGAATAGGAACCGAAGTTGCCAAAGGAA
AAGAAGTCATTACTATTGACGGCAAAGATTACCTTCTTGAAACGCCTTTAAAAGCTGATGTCGCACTTATTTTTGCTAAC
AAGGCAGATAAAAATGGCAATTTGCAATACGCAGGTTCTGAAAATAACTTTAATCATGTGATGGCTGCTAATGCGAAAAC
CACCATTGTTGAAGCAAGAGAAATTGTTGACGTGGGGCAAATGGATCCTAATTTTGTCCATACTCCTGGCATTTTTGTTA
ACTACTTAGTGAAAGGAGCCTAA

Upstream 100 bases:

>100_bases
TGAAAAAACGCCAAGTAACCAGAGGACTAGCAACACTTTGCATTGGTGGAGGACAAGGAACTGCTGTTATCGTGAAAAAC
AATACTTAGTCTCGTGAAAG

Downstream 100 bases:

>100_bases
CATGGGAACATCAGCTACTGTTCTTTCAAAAGAAGAGATTCAAACACGTATTGCTAAGCGCGTTGCACAAGAATTAGAAC
ACAATACACTGGTCAACTTA

Product: acetate CoA-transferase alpha subunit

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MVEKMCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVKDLTLICNDAGFPDKGVGKMVANKQFSTIIASH
IGLNREAGRQMTEGETVIDLVPQGTLAERIRSGGFGLGGFLTPTGIGTEVAKGKEVITIDGKDYLLETPLKADVALIFAN
KADKNGNLQYAGSENNFNHVMAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA

Sequences:

>Translated_220_residues
MVEKMCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVKDLTLICNDAGFPDKGVGKMVANKQFSTIIASH
IGLNREAGRQMTEGETVIDLVPQGTLAERIRSGGFGLGGFLTPTGIGTEVAKGKEVITIDGKDYLLETPLKADVALIFAN
KADKNGNLQYAGSENNFNHVMAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA
>Mature_220_residues
MVEKMCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVKDLTLICNDAGFPDKGVGKMVANKQFSTIIASH
IGLNREAGRQMTEGETVIDLVPQGTLAERIRSGGFGLGGFLTPTGIGTEVAKGKEVITIDGKDYLLETPLKADVALIFAN
KADKNGNLQYAGSENNFNHVMAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=225, Percent_Identity=43.5555555555556, Blast_Score=182, Evalue=2e-46,
Organism=Homo sapiens, GI11545841, Length=225, Percent_Identity=40.8888888888889, Blast_Score=153, Evalue=1e-37,
Organism=Escherichia coli, GI1788551, Length=211, Percent_Identity=52.132701421801, Blast_Score=230, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17531517, Length=230, Percent_Identity=39.1304347826087, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21358325, Length=225, Percent_Identity=43.1111111111111, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24655794, Length=225, Percent_Identity=43.1111111111111, Blast_Score=182, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 23466; Mature: 23466

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEKMCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVKDLTLICNDAGFP
CHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCC
DKGVGKMVANKQFSTIIASHIGLNREAGRQMTEGETVIDLVPQGTLAERIRSGGFGLGGF
CCCCHHHHHCHHHHHHHHHHCCCCHHHCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCCC
LTPTGIGTEVAKGKEVITIDGKDYLLETPLKADVALIFANKADKNGNLQYAGSENNFNHV
CCCCCCCCHHHCCCEEEEECCCCEEEECCCCCCEEEEEEECCCCCCCEEEECCCCCCCEE
MAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA
EECCCCHHHHHHHHHHHHCCCCCCEEECCCCEEHHEECCC
>Mature Secondary Structure
MVEKMCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVKDLTLICNDAGFP
CHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCC
DKGVGKMVANKQFSTIIASHIGLNREAGRQMTEGETVIDLVPQGTLAERIRSGGFGLGGF
CCCCHHHHHCHHHHHHHHHHCCCCHHHCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCCC
LTPTGIGTEVAKGKEVITIDGKDYLLETPLKADVALIFANKADKNGNLQYAGSENNFNHV
CCCCCCCCHHHCCCEEEEECCCCEEEECCCCCCEEEEEEECCCCCCCEEEECCCCCCCEE
MAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA
EECCCCHHHHHHHHHHHHCCCCCCEEECCCCEEHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]