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The map label for this gene is atoA [H]

Identifier: 94994851

GI number: 94994851

Start: 1390964

End: 1391623

Strand: Direct

Name: atoA [H]

Synonym: MGAS10750_Spy1455

Alternate gene names: 94994851

Gene position: 1390964-1391623 (Clockwise)

Preceding gene: 94994850

Following gene: 94994852

Centisome position: 71.81

GC content: 41.67

Gene sequence:

>660_bases
ATGGGAACATCAGCTACTGTTCTTTCAAAAGAAGAGATTCAAACACGTATTGCTAAGCGCGTTGCACAAGAATTAGAACA
CAATACACTGGTCAACTTAGGCATAGGTTTGCCAACAAAAGTAGCCAACTATATTCCTAAAGGCGTAACCATTACCCTGC
AGTCCGAAAATGGTTTTGTCGGTCTCACTGGATTAACAGATGATCACTACGATCCTACTATTGTTAATGCTGGTGGGCAA
CCTGTTAGTATTGCTCCTGGAGGGGCTTTCTTCGATAGCTCAACTTCCTTTGGTATTATTCGAGGCGGCCATGTGGCCGC
AACCGTCTTAGGTGCCTTACAAGTTGATAAAGAAGCTAGCATTGCTAATTACCTGATTCCTGGAAAAATGGTTCCTGGGA
TGGGAGGGGCCATGGACTTATTGGTAGGTGCTAAAAAAGTGATTGTTGCAATGGAGCATACCAATAAAGGCAAAGCAAAA
ATTTTAGACAAATGCACCCTTCCTCTGACTGCTCAAAATGTTGTTAACCTAATCATTACTGAAATGGGAGTCTTTGAATA
TCAAGATGAAGGTCTATGCGCCCTTGAAATTAACCCCGATTACACCTTTGAAGACGTGCAAAACGTTACCGAAGTTACCC
TAATTGATAAAACAAACTAA

Upstream 100 bases:

>100_bases
ATTGTTGAAGCAAGAGAAATTGTTGACGTGGGGCAAATGGATCCTAATTTTGTCCATACTCCTGGCATTTTTGTTAACTA
CTTAGTGAAAGGAGCCTAAC

Downstream 100 bases:

>100_bases
AGACTAACCAAAAGAAAGACGAGGATAGTATCATGACACATACTAAAGAAGTTGCATTTATCACTGGTGCTGCAAGCGGA
ATTGGAAAACAAATCGGGGA

Product: acetate CoA-transferase beta subunit

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit beta [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPKGVTITLQSENGFVGLTGLTDDHYDPTIVNAGGQ
PVSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKTN

Sequences:

>Translated_219_residues
MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPKGVTITLQSENGFVGLTGLTDDHYDPTIVNAGGQ
PVSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKTN
>Mature_218_residues
GTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPKGVTITLQSENGFVGLTGLTDDHYDPTIVNAGGQP
VSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAKI
LDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKTN

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=213, Percent_Identity=48.8262910798122, Blast_Score=194, Evalue=6e-50,
Organism=Homo sapiens, GI11545841, Length=205, Percent_Identity=45.3658536585366, Blast_Score=179, Evalue=2e-45,
Organism=Escherichia coli, GI1788552, Length=204, Percent_Identity=56.8627450980392, Blast_Score=239, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17531517, Length=212, Percent_Identity=44.811320754717, Blast_Score=167, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24655794, Length=198, Percent_Identity=47.979797979798, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21358325, Length=198, Percent_Identity=47.979797979798, Blast_Score=189, Evalue=2e-48,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 23186; Mature: 23055

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPKGVTITLQSENGFV
CCCCCCEECHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCEEEEEECCCCEE
GLTGLTDDHYDPTIVNAGGQPVSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEAS
EEECCCCCCCCCEEECCCCCEEEECCCCCEECCCCCEEEEECCHHHHHHHHHHHCCCCCC
IANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAKILDKCTLPLTAQNVVNLIIT
HHHEECCCCCCCCCCCHHHHHHCCEEEEEEEECCCCCCCEEHHHCCCCCCHHHHHHHHHH
EMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKTN
HCCCEEECCCCEEEEEECCCCCHHHHCCCEEEEEEECCC
>Mature Secondary Structure 
GTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPKGVTITLQSENGFV
CCCCCEECHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCEEEEEECCCCEE
GLTGLTDDHYDPTIVNAGGQPVSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEAS
EEECCCCCCCCCEEECCCCCEEEECCCCCEECCCCCEEEEECCHHHHHHHHHHHCCCCCC
IANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAKILDKCTLPLTAQNVVNLIIT
HHHEECCCCCCCCCCCHHHHHHCCEEEEEEEECCCCCCCEEHHHCCCCCCHHHHHHHHHH
EMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKTN
HCCCEEECCCCEEEEEECCCCCHHHHCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]