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The map label for this gene is opuCB [H]

Identifier: 94994401

GI number: 94994401

Start: 952102

End: 953664

Strand: Direct

Name: opuCB [H]

Synonym: MGAS10750_Spy1005

Alternate gene names: 94994401

Gene position: 952102-953664 (Clockwise)

Preceding gene: 94994400

Following gene: 94994402

Centisome position: 49.15

GC content: 39.67

Gene sequence:

>1563_bases
ATGCTTTTGTGGCCAATTTATTTGGAGGTGATGAGCATGCCTAGTTTGTTTGTAACTTTCCAAAACCGTTTTAATGAATG
GCTGGCGGCTCTGGGGGAACACCTGCAAATTTCCCTTTTATCTCTTATGATCGCCTTGCTAATAGGCGTGCCTTTAGCAG
CTCTTCTCAGTCGCAGCAAACGTTGGTCAGACATTATGTTACAGGTAACAGGTGTTTTTCAAACCATTCCCTCACTGGCT
TTGCTTGGTCTTTTCATCCCTTTAATGGGAATTGGAACGTTGCCTGCAGTGACAGCTTTAGTTATCTATGCGATTTTTCC
GATTTTACAGAACACCATCACAGGGTTAAATGGTATTGACCCAAGTCTCGTGGAAGCAGGAATAGCTTTTGGGATGACCA
AATGGGAGCGGTTAAAAACGTTTGAGATTCCAATTGCCATGCCTGTCATTATGTCAGGTGTGCGAACGTCAGCAGTCATG
ATTATCGGCACAGCTACTTTAGCTTCCTTGATAGGAGCCGGTGGACTTGGCTCTTTCATCTTATTGGGGATCGATCGTAA
TAATGCTAATCTGATTCTGATAGGGGCTATTTCTTCAGCTCTGCTAGCTATTATTTTCAATAGTTTGTTACAGTACCTTG
AGAAAGCTTCCTTGCGACGGATTATAATTAGTTTTGGAATCACCTTACTTGCATTGCTAGCATCGTATACTCCTATGGCG
CTTAGTCAGTTTTCAAAAGGAAAAGATACAGTGGTTATTGCCGGTAAATTGGGAGCAGAGCCCGATATTCTGATTAATCT
CTATAAGGAATTAATTGAAGACCAATCAGATATAAGCGTTGAGTTGAAATCTAATTTTGGGAAAACTAGCTTCTTATATG
AAGCCCTTAAATCTGGAGATATTGATATCTATCCTGAATTTACAGGAACTATAACATCAAGTCTTTTACGCGACAAACCA
CCGTTGTCTAATGACCCTAAGCAGGTCTATGAGGATGCTAAAAAAGGCATTGCTAAGCAAGATAAACTGACCCTTCTTAA
GCCATTTGCTTACCAAAATACGTATGCTGTTGCTATGCCAGAAAAATTGGCTAAGGAATATCAGATTGAAACCATTTCTG
ATTTAAAAGCGCATGCTGATACTTTAAAGGCTGGTTTTACTCTGGAATTTAAGGACAGAGCAGATGGCTATAAGGGAATG
CAATCTCAATATGGATTACAGCTATCTGTGGCGACGATGGAGCCAGCTCTTCGTTATCAAGCAATTCAATCAGGAGATAT
CCAAGTAACAGATGCTTACTCTACGGATGCTGAAATTACGAAATACCATTTGAAAGTTTTAAAAGATGATAAACAGTTGT
TTCCACCTTATCAGGGAGCTCCTTTGATGAAAACTTCCTTATTAACAAAACATCCAGAATTAAAAGGCATTCTTAATCAA
TTAGCGGGAAAAATTACTGAAAAAGAGATGCAGGACATGAACTACGAGGTATCTGTTAAAGGAGCAGATGCTAATAAGGT
CGCTCGAGATTATCTGTTGAAAACAGGCTTAATCCAGAAATAA

Upstream 100 bases:

>100_bases
ATTGATGAGGCTATTAAATTAGGAGACCGCGTGGCTATTTTAAATGAGGGAGAAATTGTGCAACTGGATCGCCCAGAAAT
GATTAAGACCCACCCTGCTA

Downstream 100 bases:

>100_bases
ACAGAAATGTTGGTCCGTAGGACTGGCATTTTTTCGTCTCTTAAGTTCAAGAAGTAACAATTCATAAATACAAAAACCGA
ACTTTAAAATTAAAAATAGC

Product: glycine betaine transport system permease protein / glycine betaine-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MLLWPIYLEVMSMPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSKRWSDIMLQVTGVFQTIPSLA
LLGLFIPLMGIGTLPAVTALVIYAIFPILQNTITGLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVM
IIGTATLASLIGAGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIIISFGITLLALLASYTPMA
LSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGDIDIYPEFTGTITSSLLRDKP
PLSNDPKQVYEDAKKGIAKQDKLTLLKPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGM
QSQYGLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPLMKTSLLTKHPELKGILNQ
LAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK

Sequences:

>Translated_520_residues
MLLWPIYLEVMSMPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSKRWSDIMLQVTGVFQTIPSLA
LLGLFIPLMGIGTLPAVTALVIYAIFPILQNTITGLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVM
IIGTATLASLIGAGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIIISFGITLLALLASYTPMA
LSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGDIDIYPEFTGTITSSLLRDKP
PLSNDPKQVYEDAKKGIAKQDKLTLLKPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGM
QSQYGLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPLMKTSLLTKHPELKGILNQ
LAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK
>Mature_520_residues
MLLWPIYLEVMSMPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSKRWSDIMLQVTGVFQTIPSLA
LLGLFIPLMGIGTLPAVTALVIYAIFPILQNTITGLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVM
IIGTATLASLIGAGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIIISFGITLLALLASYTPMA
LSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGDIDIYPEFTGTITSSLLRDKP
PLSNDPKQVYEDAKKGIAKQDKLTLLKPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGM
QSQYGLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPLMKTSLLTKHPELKGILNQ
LAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=197, Percent_Identity=37.0558375634518, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788452, Length=280, Percent_Identity=28.2142857142857, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1788451, Length=227, Percent_Identity=33.0396475770925, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789033, Length=176, Percent_Identity=35.2272727272727, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 57015; Mature: 57015

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLWPIYLEVMSMPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSK
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTITGLNGID
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIGAGGLGSFI
HHHHHHHHHHCCHHHHHHEEEECCHHHHHHHHCCCHHHEEEEEHHHHHHHHCCCCCCCEE
LLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIIISFGITLLALLASYTPMA
EEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGD
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCC
IDIYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLLKPFAYQNTYAVAMP
CEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHEECCHHCCCEEEEECC
EKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQYGLQLSVATMEPALRYQ
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCCCEEEEEHHCHHHHHH
AIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPLMKTSLLTKHPELKGILNQ
HHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHCCCHHHHHHHH
LAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK
HHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLWPIYLEVMSMPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSK
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTITGLNGID
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIGAGGLGSFI
HHHHHHHHHHCCHHHHHHEEEECCHHHHHHHHCCCHHHEEEEEHHHHHHHHCCCCCCCEE
LLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIIISFGITLLALLASYTPMA
EEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGD
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCC
IDIYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLLKPFAYQNTYAVAMP
CEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHEECCHHCCCEEEEECC
EKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQYGLQLSVATMEPALRYQ
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCCCEEEEEHHCHHHHHH
AIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPLMKTSLLTKHPELKGILNQ
HHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHCCCHHHHHHHH
LAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK
HHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]