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The map label for this gene is infC [H]

Identifier: 94994102

GI number: 94994102

Start: 682846

End: 683376

Strand: Direct

Name: infC [H]

Synonym: MGAS10750_Spy0706

Alternate gene names: 94994102

Gene position: 682846-683376 (Clockwise)

Preceding gene: 94994101

Following gene: 94994103

Centisome position: 35.25

GC content: 37.48

Gene sequence:

>531_bases
GTGAAGATCATAGCTAAAAAGGATCTATTCATTAATGATGAAATTCGCGTTCGCGAAGTTCGTCTCGTTGGTCTTGAAGG
TGAACAATTAGGTATTAAACCATTGTCTGAAGCGCAATCATTGGCTGATGCTTCAAATGTTGATTTGGTTTTAATCCAGC
CACAAGCTGTTCCTCCTGTTGCCAAACTTATGGACTATGGAAAGTTCAAATTTGAGTATCAAAAGAAACAGAAAGAACAA
CGTAAAAAACAAAGCGTTGTGACTGTGAAAGAAGTTCGTCTCAGTCCAGTTATCGATAAAGGTGACTTTGAAACAAAACT
TCGTAACGGTCGTAAATTCCTTGAAAAAGGAAATAAAGTTAAGGTTTCTATTCGTTTCAAAGGACGTATGATTACTCATA
AAGAGATTGGTGCCAAGGTACTAGCTGACTTTGCTGAAGCGACTCAAGATATTGCTATCATTGAGCAACGAGCAAAAATG
GATGGACGCCAAATGTTTATGCAACTTGCACCAATTTCAGACAATAAGTAA

Upstream 100 bases:

>100_bases
TAGGTTGTCTGGCCCTAACATGTCAAATTCCTATGGAATATTATATGTGCGGGCTTGATTTATCAAGTCCGCTTTCGTTT
TTCTCTAAAAAAATAAAGAG

Downstream 100 bases:

>100_bases
TTGTCACAGTTTCATTATATCTTTAAGAGGAGAATACTAAAATGCCAAAACAAAAAACACACCGCGCATCAGCTAAACGT
TTTAAACGTACAGGTTCAGG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADASNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQ
RKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
DGRQMFMQLAPISDNK

Sequences:

>Translated_176_residues
MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADASNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQ
RKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
DGRQMFMQLAPISDNK
>Mature_176_residues
MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADASNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQ
RKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
DGRQMFMQLAPISDNK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=162, Percent_Identity=51.8518518518518, Blast_Score=150, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20040; Mature: 20040

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADASNVDLVLIQPQAVPPV
CCEEECCCCEECCCEEEEEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCHH
AKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKV
HHHHHCCCCCHHHHHHHHHHHHHHHCEEHHHEEECCCCCCCCHHHHHHHHHHHHHCCCEE
KVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKMDGRQMFMQLAPISDNK
EEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADASNVDLVLIQPQAVPPV
CCEEECCCCEECCCEEEEEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCHH
AKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKV
HHHHHCCCCCHHHHHHHHHHHHHHHCEEHHHEEECCCCCCCCHHHHHHHHHHHHHCCCEE
KVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKMDGRQMFMQLAPISDNK
EEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA