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The map label for this gene is cmk [H]

Identifier: 94994101

GI number: 94994101

Start: 682004

End: 682684

Strand: Direct

Name: cmk [H]

Synonym: MGAS10750_Spy0705

Alternate gene names: 94994101

Gene position: 682004-682684 (Clockwise)

Preceding gene: 94994100

Following gene: 94994102

Centisome position: 35.21

GC content: 40.09

Gene sequence:

>681_bases
ATGAAAGCAATTAAAATTGCGATTGATGGGCCAGCTTCAAGTGGAAAAAGTACAGTAGCCAAGATTATTGCAAAAAATCT
TGGCTATACTTATCTAGATACTGGTGCTATGTATCGCTCAGCAACTTATATCGCACTGACACATGGCTATACGGGTAAAG
AAGTAGCCCTTATTTTAGAGGAACTTGAGAAAAATCCTATTTCCTTTAAAAAAGCAAAAGATGGCTCCCAATTAGTTTTT
CTTGGGGATGAGGACGTGACCTTAGCCATTAGGCAAAATGATGTGACTAACAATGTTTCTTGGGTCTCAGCTTTGCCAGA
AATTAGAGAAGAGCTGGTTCATCAACAAAGACGCATTGCACAAGCTGGTGGCATTATCATGGATGGTCGTGACATTGGAA
CGGTTGTTCTCCCAGATGCGGAACTAAAAATCTTTTTAGTGGCTTCTGTCGAAGAGCGGGCAGAGCGCCGCTATAAAGAA
AACCTAGAAAAAGGAATTGAATCAGATTTTGAGACGCTAAAAGAAGAGATTGCAGCTCGTGATTACAAGGATAGTCATCG
TAAGGTTTCACCTCTAAAATCAGCTGAAGATGCCCTTATTTTTGATACCACAGGTGTTTCTATTGATGGCGTGGTGCAAT
TTATCCAAGAAAAAGCAGAAAAAATAGTTGACATGTCCTAG

Upstream 100 bases:

>100_bases
TGGAGCAGTTACAAGCACTTAATCCAGAGCACATGACTCAAGGATATTGGTATGCCAATCCAGGAGATCAAGTCACTATT
AAATAATTGAAGAGGAAAAA

Downstream 100 bases:

>100_bases
AGCCTATGTTAGAATAGTAACAATGAGAAAAGCAGAAGTGAGAGCTTCTCGCCTTGCGACTTAGGTTGTCTGGCCCTAAC
ATGTCAAATTCCTATGGAAT

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTGKEVALILEELEKNPISFKKAKDGSQLVF
LGDEDVTLAIRQNDVTNNVSWVSALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKSAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS

Sequences:

>Translated_226_residues
MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTGKEVALILEELEKNPISFKKAKDGSQLVF
LGDEDVTLAIRQNDVTNNVSWVSALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKSAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS
>Mature_226_residues
MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTGKEVALILEELEKNPISFKKAKDGSQLVF
LGDEDVTLAIRQNDVTNNVSWVSALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKSAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787139, Length=211, Percent_Identity=44.0758293838863, Blast_Score=158, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003136
- InterPro:   IPR011994 [H]

Pfam domain/function: PF02224 Cytidylate_kin [H]

EC number: =2.7.4.14 [H]

Molecular weight: Translated: 24977; Mature: 24977

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTGKEVALILE
CCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCHHHHCEEEEEEECCCCCHHHHHHHH
ELEKNPISFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWVSALPEIREELVHQQRRIA
HHCCCCCCEEECCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKENLEKGIESDFETLKEEIAAR
HHCCEEECCCCCCEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DYKDSHRKVSPLKSAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS
CCCHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTGKEVALILE
CCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCHHHHCEEEEEEECCCCCHHHHHHHH
ELEKNPISFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWVSALPEIREELVHQQRRIA
HHCCCCCCEEECCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKENLEKGIESDFETLKEEIAAR
HHCCEEECCCCCCEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DYKDSHRKVSPLKSAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS
CCCHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]