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The map label for this gene is agaS [H]

Identifier: 94994024

GI number: 94994024

Start: 595376

End: 596575

Strand: Direct

Name: agaS [H]

Synonym: MGAS10750_Spy0628

Alternate gene names: 94994024

Gene position: 595376-596575 (Clockwise)

Preceding gene: 94994023

Following gene: 94994027

Centisome position: 30.74

GC content: 42.75

Gene sequence:

>1200_bases
ATGTTTACAAAAACGCAGGAAGCTTTGGAGGCTCTTGGTGCAGCTATCACTACCAAGGAAATTAAACAAGAACCCCGTTT
ATGGCAAGAAACCATGACGTTTTTTGACGAAACAAGAGATTCTCTGGATTCTTTTTTAAAGAGAGTTTGTAAAAGCGCTA
ACGGAAATAACGTTCATGTCATCTTTACAGGTGCGGGTACATCTGAGTACATCGGTAATACCATTTGCCCTTACTTGAAG
AAGGTGGGGAATCGGCAGTGCTATCTCTTTGAGAGTGTTGCTTCAACCGATTTGGTTGCGGCGCCAGATTATTATCTTGC
TGAGGAAGAGACGGTACTATTAGTCTCCTTTGCTAGGAGTGGTAATAGTCCAGAAAGTGTAGCGGCTGTTAACCTGGTCA
ATCAACTAGTGCCAAATAGTTATCATTTAACCATTACGTGTGCCAAAGATGGAGAACTGGCGAAAAAAGCACAGCAAGAT
GAGCGTTCTTACCTTTATTTGATGCCTGAAGACGCTAATGATGCTGGTTTTGCCATGACTGGTAGTTTTACCTGTATGAT
GCTAGCGGCTCTTTTGATTTTTGATGATGCTAACAGTATAGCTCAGAAAGAAGCTTATGTGACTGATATGATTCTTGCTG
GGCAAGCTGTTATTGACCAAGAAAGACGGCTACAAGAGCTAGCTGATTTAGGATTTGAACGTTTAGTTTATCTAGGTTCT
GCTGGTTTAGCCAAGTTAACCCAGGAGGCTCAACTAAAAATGCTAGAATTGACTGCTGGTCAGGTTGCAACAGTTTATGA
GTCTTCGATGGGATTTAGGCATGGTCCGAAATCTTTTATTAATGACCGTACCTTAGTCATTGGATTTGTCAATAATGATG
CTTACGTCAGACAGTACGATTTGGACATGTTAGAGGAAATCCAAGCAGATGGCATTGCCCTTAAAACCTTGGCTCTATTG
CAAGGAGGGGATATCAACTTTTCAGAGGACCAATTCCGACTAGACACCCGTCACTTATTGCCAGACGCTTACTTAGCTTT
TCCCATGATTTTAGTCGCGCAGACCTTGGCCCTCTTAACGGCCGTTACATTAGGAAATTCCCCTGACACCCCATCTGCGA
CAGGAATGGTTAATCGTGTGGTCAAAGGAGTAACGATTCACCCTTACCCGACTAGTAGTCGTCAATGCAACAAAGCTTAA

Upstream 100 bases:

>100_bases
AATATTTTGATCGAATTTACTTTCAGTATTGCAAGAGCAGACCAGTTTAGGTATAGGGTACAACATCACCCCAATGGTTA
AAGAAATGGGAGGTTAATAC

Downstream 100 bases:

>100_bases
AGCTTTTGTGTAGAAGCCGTAAAACGAAATGATTTTGTGCTAGTAGGCCAAAAGAAAAGACCCTCCTGATACAGGAAGGT
TTTTTGTATTATCTTGCTTA

Product: Galactosamine-6-phosphate deaminase (isomerizing)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFDETRDSLDSFLKRVCKSANGNNVHVIFTGAGTSEYIGNTICPYLK
KVGNRQCYLFESVASTDLVAAPDYYLAEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVIDQERRLQELADLGFERLVYLGS
AGLAKLTQEAQLKMLELTAGQVATVYESSMGFRHGPKSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKTLALL
QGGDINFSEDQFRLDTRHLLPDAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGMVNRVVKGVTIHPYPTSSRQCNKA

Sequences:

>Translated_399_residues
MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFDETRDSLDSFLKRVCKSANGNNVHVIFTGAGTSEYIGNTICPYLK
KVGNRQCYLFESVASTDLVAAPDYYLAEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVIDQERRLQELADLGFERLVYLGS
AGLAKLTQEAQLKMLELTAGQVATVYESSMGFRHGPKSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKTLALL
QGGDINFSEDQFRLDTRHLLPDAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGMVNRVVKGVTIHPYPTSSRQCNKA
>Mature_399_residues
MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFDETRDSLDSFLKRVCKSANGNNVHVIFTGAGTSEYIGNTICPYLK
KVGNRQCYLFESVASTDLVAAPDYYLAEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVIDQERRLQELADLGFERLVYLGS
AGLAKLTQEAQLKMLELTAGQVATVYESSMGFRHGPKSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKTLALL
QGGDINFSEDQFRLDTRHLLPDAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGMVNRVVKGVTIHPYPTSSRQCNKA

Specific function: May be a tagatose-6-phosphate ketose/aldose isomerase [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Escherichia coli, GI1789525, Length=377, Percent_Identity=43.236074270557, Blast_Score=300, Evalue=8e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001347
- InterPro:   IPR014180 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: 5.-.-.- [C]

Molecular weight: Translated: 43861; Mature: 43861

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFDETRDSLDSFLKRVCKSANGNNVHV
CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IFTGAGTSEYIGNTICPYLKKVGNRQCYLFESVASTDLVAAPDYYLAEEETVLLVSFARS
EEECCCCHHHHCCHHHHHHHHHCCCEEEEEECCCCCCEEECCCCEECCCCEEEEEEEECC
GNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQDERSYLYLMPEDANDAGFAMT
CCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCEEEE
GSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVIDQERRLQELADLGFERLVYLGS
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHCC
AGLAKLTQEAQLKMLELTAGQVATVYESSMGFRHGPKSFINDRTLVIGFVNNDAYVRQYD
CCHHHHHHHHHHHHEEECCCCHHHHHHHCCCCCCCCHHHCCCCEEEEEEECCCCEEEEEC
LDMLEEIQADGIALKTLALLQGGDINFSEDQFRLDTRHLLPDAYLAFPMILVAQTLALLT
HHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AVTLGNSPDTPSATGMVNRVVKGVTIHPYPTSSRQCNKA
HHHCCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCC
>Mature Secondary Structure
MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFDETRDSLDSFLKRVCKSANGNNVHV
CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IFTGAGTSEYIGNTICPYLKKVGNRQCYLFESVASTDLVAAPDYYLAEEETVLLVSFARS
EEECCCCHHHHCCHHHHHHHHHCCCEEEEEECCCCCCEEECCCCEECCCCEEEEEEEECC
GNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQDERSYLYLMPEDANDAGFAMT
CCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCEEEE
GSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVIDQERRLQELADLGFERLVYLGS
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHCC
AGLAKLTQEAQLKMLELTAGQVATVYESSMGFRHGPKSFINDRTLVIGFVNNDAYVRQYD
CCHHHHHHHHHHHHEEECCCCHHHHHHHCCCCCCCCHHHCCCCEEEEEEECCCCEEEEEC
LDMLEEIQADGIALKTLALLQGGDINFSEDQFRLDTRHLLPDAYLAFPMILVAQTLALLT
HHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AVTLGNSPDTPSATGMVNRVVKGVTIHPYPTSSRQCNKA
HHHCCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 8932697 [H]