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The map label for this gene is yvoA [H]

Identifier: 94994023

GI number: 94994023

Start: 594625

End: 595356

Strand: Direct

Name: yvoA [H]

Synonym: MGAS10750_Spy0627

Alternate gene names: 94994023

Gene position: 594625-595356 (Clockwise)

Preceding gene: 94994020

Following gene: 94994024

Centisome position: 30.7

GC content: 38.8

Gene sequence:

>732_bases
GTGAATAAGATGCCAAAAGAACAACCACTCTATTTACAGATTGTTGATGCCCTAGAAGTTAAAATCAGAAAGAGCATGAC
AGCGAACGATAAGTTACTGTCAGAACGAGAACTAAGCGACCTTTACGGTGTTAGCCGCATCACGATTAGACTAGCTCTTA
AAGAATTAGAACTACGGGGCTTAATTTATAAAAAGCAGGGCAAGGGAACCTATGTTTCTGGTATCAAGGAACCCGCCACT
GATTTATCAAGTACATATAGCTTTACAGAGCAGATGAAAAAAATGGGAAAAATGCCTAAAACAGAAATTCTTTCCTTTGA
ACAGTATCAGGTAACACCTTACTTGTCTGGTCTCTTAGAGCTTGATCCCGATACAGAAGTTTTTGAATTAGAACGCCTAA
GGATTGCAGATGATATGCCCTTGATGTTTGAACGATCCTATATTCCTGCTCAGCCTTTTCAGGGGTTAAGCATTGCGGAC
TTGAAGCGTAAAGCTTTGTACGATATCTTTGCAAAGGACTATCAAGAGACAATCCGTCTTGCAGAAGAAGAGTTTTATGC
CAGCATTGCCTTGGACTATGAAGCAGACCTTTTGGGAATCAAAAAAGGAGATCCTGTCTTACATATTATTCGTAAAACTT
ATAACGATAAAAATATTTTGATCGAATTTACTTTCAGTATTGCAAGAGCAGACCAGTTTAGGTATAGGGTACAACATCAC
CCCAATGGTTAA

Upstream 100 bases:

>100_bases
TTTCTTTTATTTTTGATCAAAAAATTTTAATATTTCTAAATATTTGCTTGACTAAGAATTATTATTATAATATACTTTAG
ATGGTTATAACAAGTTAGAG

Downstream 100 bases:

>100_bases
AGAAATGGGAGGTTAATACATGTTTACAAAAACGCAGGAAGCTTTGGAGGCTCTTGGTGCAGCTATCACTACCAAGGAAA
TTAAACAAGAACCCCGTTTA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MNKMPKEQPLYLQIVDALEVKIRKSMTANDKLLSERELSDLYGVSRITIRLALKELELRGLIYKKQGKGTYVSGIKEPAT
DLSSTYSFTEQMKKMGKMPKTEILSFEQYQVTPYLSGLLELDPDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIAD
LKRKALYDIFAKDYQETIRLAEEEFYASIALDYEADLLGIKKGDPVLHIIRKTYNDKNILIEFTFSIARADQFRYRVQHH
PNG

Sequences:

>Translated_243_residues
MNKMPKEQPLYLQIVDALEVKIRKSMTANDKLLSERELSDLYGVSRITIRLALKELELRGLIYKKQGKGTYVSGIKEPAT
DLSSTYSFTEQMKKMGKMPKTEILSFEQYQVTPYLSGLLELDPDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIAD
LKRKALYDIFAKDYQETIRLAEEEFYASIALDYEADLLGIKKGDPVLHIIRKTYNDKNILIEFTFSIARADQFRYRVQHH
PNG
>Mature_243_residues
MNKMPKEQPLYLQIVDALEVKIRKSMTANDKLLSERELSDLYGVSRITIRLALKELELRGLIYKKQGKGTYVSGIKEPAT
DLSSTYSFTEQMKKMGKMPKTEILSFEQYQVTPYLSGLLELDPDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIAD
LKRKALYDIFAKDYQETIRLAEEEFYASIALDYEADLLGIKKGDPVLHIIRKTYNDKNILIEFTFSIARADQFRYRVQHH
PNG

Specific function: Acts as a weak repressor of yflG expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788418, Length=236, Percent_Identity=26.6949152542373, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790118, Length=232, Percent_Identity=25, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786950, Length=229, Percent_Identity=25.3275109170306, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082252, Length=203, Percent_Identity=26.6009852216749, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 28179; Mature: 28179

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKMPKEQPLYLQIVDALEVKIRKSMTANDKLLSERELSDLYGVSRITIRLALKELELRG
CCCCCCCCCHHEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LIYKKQGKGTYVSGIKEPATDLSSTYSFTEQMKKMGKMPKTEILSFEQYQVTPYLSGLLE
EEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHEEECHHHHHHEE
LDPDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIADLKRKALYDIFAKDYQETIRL
CCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AEEEFYASIALDYEADLLGIKKGDPVLHIIRKTYNDKNILIEFTFSIARADQFRYRVQHH
HHHHHHEEEEECCCCCEEEECCCCHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHEEEECC
PNG
CCC
>Mature Secondary Structure
MNKMPKEQPLYLQIVDALEVKIRKSMTANDKLLSERELSDLYGVSRITIRLALKELELRG
CCCCCCCCCHHEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LIYKKQGKGTYVSGIKEPATDLSSTYSFTEQMKKMGKMPKTEILSFEQYQVTPYLSGLLE
EEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHEEECHHHHHHEE
LDPDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIADLKRKALYDIFAKDYQETIRL
CCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AEEEFYASIALDYEADLLGIKKGDPVLHIIRKTYNDKNILIEFTFSIARADQFRYRVQHH
HHHHHHEEEEECCCCCEEEECCCCHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHEEEECC
PNG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]