Click here to switch to the map view.

The map label for this gene is iolC [H]

Identifier: 94993941

GI number: 94993941

Start: 527961

End: 529001

Strand: Direct

Name: iolC [H]

Synonym: MGAS10750_Spy0545

Alternate gene names: 94993941

Gene position: 527961-529001 (Clockwise)

Preceding gene: 94993940

Following gene: 94993942

Centisome position: 27.26

GC content: 42.94

Gene sequence:

>1041_bases
TTGAACAGTAATTCCATTTTGACGAGGAAAGGAGATCACATGTCTAAGTTATTATTGGTTGGTGAACCGCTGATACGCGT
TAGTCCCAATCAGTTTCAGCCTTTGACCAATGCCTGCGACGCTCAGCTTTTTTTCGGCGGTTCAGAAGTTAATATTGCAA
GAACTCTAGGCGGTTTTGGCTTAGAAGCAAGGCTATTTACGGCCCTACCAGATAATCCTGTTGGTCACGCTTTTCATCAG
TTTTTGAAGCAAAGCGGTGTGGATATGACCCTGACGGCTTGGCAGGGCAACCGTGTTGGGCTGTATTACCTTGAAAATGG
CTTTGGTTGTCGTTCTAGTCAGGTTTATTATGACCGCTGTGGCTCTAGCTTTTCGGCCTTAGATAAGGATAGTCTTGATC
TAGCTGCCATTTTTGAAGGCATTAGTCACTTTCATTTTAGTGGGATCAGTTTGGCGCTGGGCAAAAAAACTCAGGATCTG
ATTGAGATACTTGTGAGAGAAGCTAAGAAAAGGGATATTTGTGTTTCTTTTGATCTTAACTTTAGATCTAGTATGATTGC
GGTAGCTGATGCTAAACGACTCTTTTCTCATTTTGCTCAATACGCGGATATTATTTTTGGCATGGAACCTTTGCTGTTAG
ACAGTGACGATTTTGACATGTTTGATAGGAATAAGGCAGATACTACGATGATTAGAGAACGTCTGGCAGGACTTTATCAG
CGCTATCAGTTACAAGCTATTTACCATACGGAGCGTTCAAATGATGCCCAAGGCAGTAATCATTTTAAGGCTTATACCTA
TGATGGGCAGTTTTACGAATCCTGTGAAGTGACGACCCCAGTCTTGCAACGGGTTGGAAGTGGAGATGCTTTTGTGGCGG
GTTTACTTTATCAGTTGTTAGAAGGTGACGAAAAGCAGTACAACCTTGATTTTGCTGTGGCAACAGCTAGCCTAAAATGT
ACAGTAGCTGAAGATCAGCTCTATCACAGCGCCCAACAAGTAGAAGCAGTCTTAGCTAATCAACGAGATGTCCAGAGGTG
A

Upstream 100 bases:

>100_bases
CAAGATTTCCTCAAAGAAACGATTTCTGGCGCTCATTTTAAAGAGTACTTCTTTGCCAATGCGGAGCCGTCAGAATTAGT
TACTTATTTGAAATCAGTAC

Downstream 100 bases:

>100_bases
TGATATGGGAAAAATAGAAATCTTAACCAAACTTAAGGCTAATCGGCTTGTCCTGGTTGTACGAGGAGAGTCTAGTGAGG
AAGCTTTAGCTTGCAGCCTG

Product: 2-dehydro-3-deoxygluconokinase

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNSNSILTRKGDHMSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLGGFGLEARLFTALPDNPVGHAFHQ
FLKQSGVDMTLTAWQGNRVGLYYLENGFGCRSSQVYYDRCGSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDL
IEILVREAKKRDICVSFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADTTMIRERLAGLYQ
RYQLQAIYHTERSNDAQGSNHFKAYTYDGQFYESCEVTTPVLQRVGSGDAFVAGLLYQLLEGDEKQYNLDFAVATASLKC
TVAEDQLYHSAQQVEAVLANQRDVQR

Sequences:

>Translated_346_residues
MNSNSILTRKGDHMSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLGGFGLEARLFTALPDNPVGHAFHQ
FLKQSGVDMTLTAWQGNRVGLYYLENGFGCRSSQVYYDRCGSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDL
IEILVREAKKRDICVSFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADTTMIRERLAGLYQ
RYQLQAIYHTERSNDAQGSNHFKAYTYDGQFYESCEVTTPVLQRVGSGDAFVAGLLYQLLEGDEKQYNLDFAVATASLKC
TVAEDQLYHSAQQVEAVLANQRDVQR
>Mature_346_residues
MNSNSILTRKGDHMSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLGGFGLEARLFTALPDNPVGHAFHQ
FLKQSGVDMTLTAWQGNRVGLYYLENGFGCRSSQVYYDRCGSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDL
IEILVREAKKRDICVSFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADTTMIRERLAGLYQ
RYQLQAIYHTERSNDAQGSNHFKAYTYDGQFYESCEVTTPVLQRVGSGDAFVAGLLYQLLEGDEKQYNLDFAVATASLKC
TVAEDQLYHSAQQVEAVLANQRDVQR

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 38725; Mature: 38725

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSNSILTRKGDHMSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLGGFG
CCCCCEEEECCCHHHHHHEECCCCEEECCCCCCCHHHCCCCEEEECCCCEEEEHHHCCCC
LEARLFTALPDNPVGHAFHQFLKQSGVDMTLTAWQGNRVGLYYLENGFGCRSSQVYYDRC
CEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCCCCCCCCHHHHC
GSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDLIEILVREAKKRDICVSFDLN
CCCHHHCCCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECC
FRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADTTMIRERLAGLYQ
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
RYQLQAIYHTERSNDAQGSNHFKAYTYDGQFYESCEVTTPVLQRVGSGDAFVAGLLYQLL
HHHHHEEEECCCCCCCCCCCCEEEEEECCCEECCCCCCHHHHHHCCCCCHHHHHHHHHHH
EGDEKQYNLDFAVATASLKCTVAEDQLYHSAQQVEAVLANQRDVQR
CCCCCCEEEEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHCHHCCCC
>Mature Secondary Structure
MNSNSILTRKGDHMSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLGGFG
CCCCCEEEECCCHHHHHHEECCCCEEECCCCCCCHHHCCCCEEEECCCCEEEEHHHCCCC
LEARLFTALPDNPVGHAFHQFLKQSGVDMTLTAWQGNRVGLYYLENGFGCRSSQVYYDRC
CEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCCCCCCCCHHHHC
GSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDLIEILVREAKKRDICVSFDLN
CCCHHHCCCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECC
FRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADTTMIRERLAGLYQ
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
RYQLQAIYHTERSNDAQGSNHFKAYTYDGQFYESCEVTTPVLQRVGSGDAFVAGLLYQLL
HHHHHEEEECCCCCCCCCCCCEEEEEECCCEECCCCCCHHHHHHCCCCCHHHHHHHHHHH
EGDEKQYNLDFAVATASLKCTVAEDQLYHSAQQVEAVLANQRDVQR
CCCCCCEEEEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA