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The map label for this gene is ftsY [H]

Identifier: 94993890

GI number: 94993890

Start: 475316

End: 476866

Strand: Direct

Name: ftsY [H]

Synonym: MGAS10750_Spy0494

Alternate gene names: 94993890

Gene position: 475316-476866 (Clockwise)

Preceding gene: 94993889

Following gene: 94993892

Centisome position: 24.54

GC content: 43.39

Gene sequence:

>1551_bases
ATGGGATTATTTGATCGTTTATTTGGGAAAAAAGAAACCCCGAAGGTAGCTGAGGAAAAGTTAGAAGAAAATCTTTTGAC
AGAAACAACTCAGAAAGAGGAGCTTTCTGAAAAAGCCAATGAGCAAGACAAGATTGAGGCGGTTCAACAAGAGGACGTTT
CTTCAGAGGGCGCAGGTTCGGTGGAAAATGGTCCCGAAGCAGCTTCAGTAAACGCACCGGTTGAGGAAGAAACAGGTGAC
AATAGTAATCATCCATCAGAAGATACCAATAAGTTTGCTGCCGACAAAACAGACCTTAAGGTAAGTGAACTTAGTCAATC
TACGGCATCAGAACCAAAAGACCTTGTTGACCAGCCAGTTGTGGAACAGTTTCCAACAAAACAAGCCCAAGCTGATGCCT
CAAATGATTCGGCGAATGAAGAAGCAGTAGACACTTCAAAAGAGCAATCCAGTAGCCAACAGGTTATGGAAGACTACTAT
CGTCGTAAGGCTGCTCTTGAAAAAAGTCTTCAAGAAAAAGCAGCGGCAACGGTTCCAGTGATGCCAGAAGAGGTTCCACA
AGAAAATCAGGCCTCTACCTCAGCAGAAGCTTCTCAAAACAAGGCAACCTACGATACCATTCCTGAGACAGATCAAGAAA
AATACAAGCGTAGCTTGAAAAAAACGCGGACTGGCTTCTCAGCTCGTCTGAACAGTTTCTTTGCCAATTTCAGGCGAGTG
GATGAAGAATTCTTTGAAGACTTGGAAGAAATGCTGATCTTATCAGATGTCGGTGTACATGTGGCGACAACTTTGACAGA
GGAGTTGCGTTATGAAGCCAAACTGGAAAATGCGAAAAAACCAGATGCCTTGAAACGTGTGATTGTGGAAAAATTGGTAG
ATATCTATGAAAAAGATGGGCGTTATAATGAAGCCATTAATTATCAAGATGGATTGACGGTTATGCTTTTTGTAGGTGTT
AACGGGGTTGGTAAAACGACTTCAATCGGGAAGCTGGCTTACCGTTACAAACAAGAAGGTAAAAAAGTCATGTTGGTGGC
AGCAGATACCTTCCGAGCAGGGGCTGTGGCTCAGCTAGTCGAATGGGGACGCCGAGTAGATGTGCCAGTCATTACTGGCC
CTGAAAAGGCTGATCCAGCGTCTGTTGTTTTTGACGGGATGGAAAAAGCTGTGGCAAAAGGTGTAGATATTCTCCTGATT
GACACGGCTGGTCGCCTGCAGAACAAAGAAAATCTCATGGCAGAGCTGGAAAAAATGGGTCGTATCATTAAGCGCGTGCT
ACCAGATGCCCCTCATGAAACGCTTTTGGCCTTAGATGCGTCAACAGGTCAAAATGCGCTTAGCCAAGCCAAGGAATTTT
CAAAAATAACACCTTTAACAGGCTTAATTTTAACGAAAATTGATGGGACTGCAAAAGGTGGGGTGGTCCTAGCCATCCGT
CAAGAATTAGACATTCCAGTCAAGTTTATCGGATTTGGTGAAAAAGTGGATGATATTGGAGAATTCCACTCAGAAGACTT
TATGAAAGGTCTTTTAGAAGGTATTTTATAA

Upstream 100 bases:

>100_bases
CAGGAGCTAAAGCCGTTGCCGATGCCGTGACCACCTTGACCAATGATGAGTCTGGAGTTGCAGAAGCTGTGAAGACATTT
ATTTTAGAAGAGGAGAGTTA

Downstream 100 bases:

>100_bases
GAAAAAAACCAGTCTTGTTCAACAGAACGAGGCTGGTTTTTAAGTAAGTCAGCTTAGGCTAATCCTTTTTTCCCTAAATG
GTAAAACATAGCAAAGAAAA

Product: cell division protein ftsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDKIEAVQQEDVSSEGAGSVENGPEAASVNAPVEEETGD
NSNHPSEDTNKFAADKTDLKVSELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYY
RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATYDTIPETDQEKYKRSLKKTRTGFSARLNSFFANFRRV
DEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLENAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGV
NGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVAKGVDILLI
DTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGVVLAIR
QELDIPVKFIGFGEKVDDIGEFHSEDFMKGLLEGIL

Sequences:

>Translated_516_residues
MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDKIEAVQQEDVSSEGAGSVENGPEAASVNAPVEEETGD
NSNHPSEDTNKFAADKTDLKVSELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYY
RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATYDTIPETDQEKYKRSLKKTRTGFSARLNSFFANFRRV
DEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLENAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGV
NGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVAKGVDILLI
DTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGVVLAIR
QELDIPVKFIGFGEKVDDIGEFHSEDFMKGLLEGIL
>Mature_515_residues
GLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDKIEAVQQEDVSSEGAGSVENGPEAASVNAPVEEETGDN
SNHPSEDTNKFAADKTDLKVSELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYYR
RKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATYDTIPETDQEKYKRSLKKTRTGFSARLNSFFANFRRVD
EEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLENAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGVN
GVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVAKGVDILLID
TAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGVVLAIRQ
ELDIPVKFIGFGEKVDDIGEFHSEDFMKGLLEGIL

Specific function: Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=199, Percent_Identity=36.6834170854271, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4507215, Length=199, Percent_Identity=36.6834170854271, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI295424842, Length=307, Percent_Identity=27.0358306188925, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI23308697, Length=307, Percent_Identity=27.0358306188925, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI89061728, Length=135, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1789874, Length=300, Percent_Identity=45.6666666666667, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1788963, Length=193, Percent_Identity=40.4145077720207, Blast_Score=138, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17539958, Length=273, Percent_Identity=32.2344322344322, Blast_Score=138, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI193206261, Length=296, Percent_Identity=28.3783783783784, Blast_Score=96, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6325345, Length=261, Percent_Identity=34.0996168582375, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI17647949, Length=265, Percent_Identity=30.188679245283, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24641198, Length=223, Percent_Identity=27.8026905829596, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 56779; Mature: 56648

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDKIEAVQQEDVSSEGAGS
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
VENGPEAASVNAPVEEETGDNSNHPSEDTNKFAADKTDLKVSELSQSTASEPKDLVDQPV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCCHH
VEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYYRRKAALEKSLQEKAAATVPV
HHHCCCHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MPEEVPQENQASTSAEASQNKATYDTIPETDQEKYKRSLKKTRTGFSARLNSFFANFRRV
CCHHCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLENAKKPDALKRVIVEKLVDIYEKDG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
RYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLV
CCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHH
EWGRRVDVPVITGPEKADPASVVFDGMEKAVAKGVDILLIDTAGRLQNKENLMAELEKMG
HCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHHHHH
RIIKRVLPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGVVLAIR
HHHHHHCCCCCCHHEEEEECCCCHHHHHHHHHHHHHCCHHHHHHEECCCCCCCCEEEEEE
QELDIPVKFIGFGEKVDDIGEFHSEDFMKGLLEGIL
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDKIEAVQQEDVSSEGAGS
CHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
VENGPEAASVNAPVEEETGDNSNHPSEDTNKFAADKTDLKVSELSQSTASEPKDLVDQPV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCCHH
VEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYYRRKAALEKSLQEKAAATVPV
HHHCCCHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MPEEVPQENQASTSAEASQNKATYDTIPETDQEKYKRSLKKTRTGFSARLNSFFANFRRV
CCHHCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLENAKKPDALKRVIVEKLVDIYEKDG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
RYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLV
CCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHH
EWGRRVDVPVITGPEKADPASVVFDGMEKAVAKGVDILLIDTAGRLQNKENLMAELEKMG
HCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHHHHH
RIIKRVLPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGVVLAIR
HHHHHHCCCCCCHHEEEEECCCCHHHHHHHHHHHHHCCHHHHHHEECCCCCCCCEEEEEE
QELDIPVKFIGFGEKVDDIGEFHSEDFMKGLLEGIL
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584053; 9384377; 8654983 [H]