Click here to switch to the map view.

The map label for this gene is dhaL [H]

Identifier: 94993844

GI number: 94993844

Start: 437062

End: 437706

Strand: Direct

Name: dhaL [H]

Synonym: MGAS10750_Spy0448

Alternate gene names: 94993844

Gene position: 437062-437706 (Clockwise)

Preceding gene: 94993843

Following gene: 94993845

Centisome position: 22.56

GC content: 44.19

Gene sequence:

>645_bases
TTGACAAGGATGAATGGACAGAAGCTCTTCAATCAGATGTTATCACACCAGCTTGGTAAGGAGGAAATCATGCAAGCACA
AGATGCAATCAAATGGATGACCTTATTTAATGATAAAATTCAAGTGAATAAGGATTATTTAAGTCAATTGGATACGCCTA
TCGGAGATGGTGACCACGGTGGCAATATGGCGCGCGGGATGTCTGCTGTGATGGAAAATCTTGACGGTAAAGAATTTGCG
AGCGCAGCGGATGTCTTTAAGGTCGTTGCTATGCAGTTGCTAGGCAAAGTTGGTGGAGCTTCAGGCCCATTGTATGGTTC
TGCCTTTATGGGGCTTTCAAAAGCTAGTGAGGATAGCAGTTTGGCAGATGCTTTGCAGGCTGGATTGGACATGATTCAAA
AACGTGGTAAGGCAGAAAAAGGTGAGAAAACCATGGTGGATGTTTGGATTCCTGTGATTGAAGCCTTGAAAAATGACGGG
TTAACCAAGGATGTGGTTGAAGAGGCTGTTTTAGCTACCAAAGACATCCAGGCAACTAAAGGACGCGCTTCTTATGTAGG
AGAACGCTCAGTGGGTCATATTGATCCAGGTTCCTTCTCATCAGGACTCTTATTTGAAGCCATGTTGGAAGCAGAGGTGG
TTTAA

Upstream 100 bases:

>100_bases
AAACTCTTAGCAGAAAAAGATGTCACAGTCAGCTTCAAGAAAATTGGTGACTACATGACGTCTATTGATATGGCTGGTTT
GTCTTTGACCTTGATCAAAC

Downstream 100 bases:

>100_bases
TGTCAAATTTAGGAATTATTATTGTATCGCATTCTAAAAATATTGCTCAAGGAGTTGTCGACCTGATTTCAGAGGTGGCG
ACAGATGTTGCCATCACCTA

Product: dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MTRMNGQKLFNQMLSHQLGKEEIMQAQDAIKWMTLFNDKIQVNKDYLSQLDTPIGDGDHGGNMARGMSAVMENLDGKEFA
SAADVFKVVAMQLLGKVGGASGPLYGSAFMGLSKASEDSSLADALQAGLDMIQKRGKAEKGEKTMVDVWIPVIEALKNDG
LTKDVVEEAVLATKDIQATKGRASYVGERSVGHIDPGSFSSGLLFEAMLEAEVV

Sequences:

>Translated_214_residues
MTRMNGQKLFNQMLSHQLGKEEIMQAQDAIKWMTLFNDKIQVNKDYLSQLDTPIGDGDHGGNMARGMSAVMENLDGKEFA
SAADVFKVVAMQLLGKVGGASGPLYGSAFMGLSKASEDSSLADALQAGLDMIQKRGKAEKGEKTMVDVWIPVIEALKNDG
LTKDVVEEAVLATKDIQATKGRASYVGERSVGHIDPGSFSSGLLFEAMLEAEVV
>Mature_213_residues
TRMNGQKLFNQMLSHQLGKEEIMQAQDAIKWMTLFNDKIQVNKDYLSQLDTPIGDGDHGGNMARGMSAVMENLDGKEFAS
AADVFKVVAMQLLGKVGGASGPLYGSAFMGLSKASEDSSLADALQAGLDMIQKRGKAEKGEKTMVDVWIPVIEALKNDGL
TKDVVEEAVLATKDIQATKGRASYVGERSVGHIDPGSFSSGLLFEAMLEAEVV

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=190, Percent_Identity=35.2631578947368, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787449, Length=188, Percent_Identity=40.4255319148936, Blast_Score=135, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323570, Length=209, Percent_Identity=28.7081339712919, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 22991; Mature: 22859

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRMNGQKLFNQMLSHQLGKEEIMQAQDAIKWMTLFNDKIQVNKDYLSQLDTPIGDGDHG
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHEECHHHHHHCCCCCCCCCCC
GNMARGMSAVMENLDGKEFASAADVFKVVAMQLLGKVGGASGPLYGSAFMGLSKASEDSS
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHH
LADALQAGLDMIQKRGKAEKGEKTMVDVWIPVIEALKNDGLTKDVVEEAVLATKDIQATK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
GRASYVGERSVGHIDPGSFSSGLLFEAMLEAEVV
CHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRMNGQKLFNQMLSHQLGKEEIMQAQDAIKWMTLFNDKIQVNKDYLSQLDTPIGDGDHG
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHEECHHHHHHCCCCCCCCCCC
GNMARGMSAVMENLDGKEFASAADVFKVVAMQLLGKVGGASGPLYGSAFMGLSKASEDSS
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHH
LADALQAGLDMIQKRGKAEKGEKTMVDVWIPVIEALKNDGLTKDVVEEAVLATKDIQATK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
GRASYVGERSVGHIDPGSFSSGLLFEAMLEAEVV
CHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]