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The map label for this gene is pgtP [H]

Identifier: 94993759

GI number: 94993759

Start: 366566

End: 367909

Strand: Direct

Name: pgtP [H]

Synonym: MGAS10750_Spy0363

Alternate gene names: 94993759

Gene position: 366566-367909 (Clockwise)

Preceding gene: 94993758

Following gene: 94993760

Centisome position: 18.92

GC content: 42.63

Gene sequence:

>1344_bases
TTGTTTATGGAAGAGGATTATAACAAAAGAGAACCTGAGAAGTTTACGCAATTTCTGCGCCGTCAAAAGGTCGTCTTTTT
TGTCGCATTTTTTGGTTATGTGTGTGCCTACTTGGTACGCAACAATTTCAAACTAATGTCAAACACTATTATGGTCCAAA
ACGGTTGGGACAAGGCTCAAATTGCGACCTTGTTATCGTGTTTGACCGTTTCTTATGGTTTAGCAAAATTCTATATGGGG
GCCTTAGGGGATCGTGTTAGCTTGAGGAAGCTCTTTTCAATCAGCTTGGGTGCAAGCGCTTTGATTTGTATTTTAATCGG
TTTTTTCAATAGTTCAATGGTGGTGTTAGGGATACTGCTAGTCTTGTGTGGTGTCGTACAAGGTGCCTTGGCACCTGCCT
CACAAGCCATGATTGCCAATTATTTTCCAAATAAAACACGCGGCGGAGCCATCGCTGGATGGAACATTTCTCAAAACATG
GGATCAGCCCTCTTGCCATTAACCATCGCCTTGCTCACCAGTATGGGCTTGGTGGTACCAGCTAATGGCAATATTTTACT
TGCCTTTTTAATCCCTGGTGTTTTAGTGTTCTTGTTTGCTTTGTGTTGCTGGAAGCTTGGCGGTGATAACCCTGAGTCTG
AGGGACTTGACTCTCTTCGAACGATGTATGGTGATGCGGGCGAATCAGCTGTTGCCAGTGAAGAAGAAAAGCATAACCTG
TCTTATTGGCAACTCATCTGGAAATACGTTTTTTGTAACCCGTCACTCTTACTTGTTGCTGCTGTCAATGTGGCCCTTTA
TTTTGTTCGTTTTGGGATTGAAGACTGGATGCCGATCTACTTGTCACAAGTAGCCAATATGTCAGAGGCCCATATTCATT
TTGCGATTTCAATATTAGAGTGGGTCGCTATTCCAGGCTCGCTGGTATTTGCGTGGTTAGCGGTTCGTTATCCTAATAAA
ATGGCCAAGATTGGGGCTATTGGGCTTTTTGTGTTAGCGGCTATTGTGTTTGTCTATGAACGCTTGACTGCCACAGGTGC
TCCAAACTATTTCTTGTTGCTTGTTATTGCAGGTATTTTAGGGTCATTGATTTATGGCCCACAGTTGATCGTGAATATTT
TAACAATCAACTTTGTTCCTTTAAATGTTGCAGGAACAGCGATTGGTTTTGTAGGAGTAACAGCTTATCTCATCGGCAAT
ATGGGAGCAAACTGGCTGATGCCGATTTTGGCAGATGGTTTTGGCTGGTTTTGGTCATATATTGTCGTTGCAGCCTTATC
TGCTTTTTCAGCGGTTGGTTATTTGATTTTAGCCAAACGTGAGGAAGAAATCATCAAAGATTAG

Upstream 100 bases:

>100_bases
TCTAGAAGCAGTGAAATCGAATTTGTAAGCGTTGACACTGCTACATAACTCTGTTACACTAAGAGAATGTCATGACAAAA
ATTACAGTGTAGGAGTTTAA

Downstream 100 bases:

>100_bases
CTAGGCAAATGCCTAAGAAAGACAGACTTATTGCTGAAGTCCTGTCTTTTTTAGGCATCACAAGCCGCAAGTGACACTAT
AAAAGACAAGAAAATGCTAG

Product: phosphoglycerate transporter protein

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MFMEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLMSNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMG
ALGDRVSLRKLFSISLGASALICILIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNM
GSALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLRTMYGDAGESAVASEEEKHNL
SYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMPIYLSQVANMSEAHIHFAISILEWVAIPGSLVFAWLAVRYPNK
MAKIGAIGLFVLAAIVFVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGN
MGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD

Sequences:

>Translated_447_residues
MFMEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLMSNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMG
ALGDRVSLRKLFSISLGASALICILIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNM
GSALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLRTMYGDAGESAVASEEEKHNL
SYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMPIYLSQVANMSEAHIHFAISILEWVAIPGSLVFAWLAVRYPNK
MAKIGAIGLFVLAAIVFVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGN
MGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD
>Mature_447_residues
MFMEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLMSNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMG
ALGDRVSLRKLFSISLGASALICILIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNM
GSALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLRTMYGDAGESAVASEEEKHNL
SYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMPIYLSQVANMSEAHIHFAISILEWVAIPGSLVFAWLAVRYPNK
MAKIGAIGLFVLAAIVFVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGN
MGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD

Specific function: The phosphoglycerate transporter protein is a part of the PGT transport system. It is the membrane bound transporter for phosphoglycerate into salmonella [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=427, Percent_Identity=23.1850117096019, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI4503847, Length=427, Percent_Identity=23.1850117096019, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI256219483, Length=427, Percent_Identity=23.1850117096019, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI256219543, Length=449, Percent_Identity=21.1581291759465, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1788573, Length=458, Percent_Identity=28.1659388646288, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI2367259, Length=393, Percent_Identity=27.4809160305344, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI87082310, Length=425, Percent_Identity=26.5882352941176, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87082320, Length=302, Percent_Identity=21.8543046357616, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48923; Mature: 48923

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLMSNTIMVQNGWDKAQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEEECCCCHHH
IATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICILIGFFNSSMVVLGILL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHH
VLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGSALLPLTIALLTSMGLVVP
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEECCCCHHHCCHHHHHHHHHHHHHCCEEEE
ANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLRTMYGDAGESAVASEEEKHNL
CCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHCCCHHHCCH
SYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMPIYLSQVANMSEAHIHFAISILE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIVFVYERLTATGAPNYFLLLVIAGIL
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGNMGANWLMPILADGFGWFWSY
HHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
IVVAALSAFSAVGYLILAKREEEIIKD
HHHHHHHHHHHHHHHHEECCHHHHHCC
>Mature Secondary Structure
MFMEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLMSNTIMVQNGWDKAQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEEECCCCHHH
IATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICILIGFFNSSMVVLGILL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHH
VLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGSALLPLTIALLTSMGLVVP
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEECCCCHHHCCHHHHHHHHHHHHHCCEEEE
ANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLRTMYGDAGESAVASEEEKHNL
CCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHCCCHHHCCH
SYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMPIYLSQVANMSEAHIHFAISILE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIVFVYERLTATGAPNYFLLLVIAGIL
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGNMGANWLMPILADGFGWFWSY
HHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
IVVAALSAFSAVGYLILAKREEEIIKD
HHHHHHHHHHHHHHHHEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 3042749 [H]