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The map label for this gene is tagO [H]

Identifier: 94993633

GI number: 94993633

Start: 248227

End: 249396

Strand: Direct

Name: tagO [H]

Synonym: MGAS10750_Spy0237

Alternate gene names: 94993633

Gene position: 248227-249396 (Clockwise)

Preceding gene: 94993632

Following gene: 94993634

Centisome position: 12.81

GC content: 37.35

Gene sequence:

>1170_bases
ATGTTTTCATTCACAATAGATTATGTCCTTGTTCTGATAGGGGCTTTGTTAATGTCCTTATTCTTAACCCCTCTTGTTCG
CTTTTTAGCCTTTCGTGTGGGTGCAGTAGACAATCCCAATGCCAGACGGGTCAATAAGGTTCCGATGCCAACCAGTGGTG
GATTAGCTATTTTTATGTCTTTTTTAGTAGCAAGTTTGGGACTTATTCCGATTGCTTCTAAAGGCGCCATGTTTTTTGGT
CAGACCTACTTCAGTTATATTTTACCTGTCGTGATTGGTGCTACAGTAATTACCCTTACTGGTTTTTTAGATGATTTGTA
TGAGTTAAGTCCTAAATTAAAGATGTTTGGTATTCTAATTGGTGCAGTGATTGTCTGGGCTTTTACCGACTTTAAATTTG
ATAGCTTCAAAATTCCTTTTGGAGGGCCGTTGTTAGTTTTTGGTCCTTTCTTAACCTTATTCTTAACAGTCCTGTGGATT
GTTTCCATCACTAATGCTATTAACTTGATTGACGGTTTGGATGGTTTGGTTAGTGGGGTCTCTATTATTAGTTTAGTGAC
CATGGCTATTGTATCTTATTTCTTTTTACCTCAAAAAGATTTCTTTTTGACGTTAACCATTTTGGTCTTGATTGCTGCTA
TTGCAGGATTTTTTCCTTATAATTACCATCCAGCTATGATTTATTTGGGTGACACAGGAGCCCTCTTTATTGGCTTTATG
ATAGGGGTTTTGTCTCTTCAAGGATTGAAAAATTCAACGGCTGTGGCTGTGGTGACACCTGTTATTATTCTTGGTGTACC
CATTATGGATACCATCGTGGCTATTATTCGACGTAGTTTATCAGGTCAAAAATTCTACGAGCCGGATAAGATGCACCTGC
ATCATCGACTCTTATCAATGGGCTTTACTCATCGAGGAGCTGTCTTAGTAGTTTATGGTATTACCATGCTTTTTTCCCTT
ATTTCTTTACTTTTAAATGTTTCTAGTCGAATTGGTGGCGTCCTCTTGATCCTTGGACTTTTATTTGGTTTAGAAGTTTT
TATTGAAGGATTGGAAATCTGGGGTGAAAAGCGAACGCCTTTGTTTAACTTGTTAAAGTTTATTGGTAATAGTGATTATC
GTCAAGCAATGCTTCTGAAATGGAAAGAAAAGAAGGATTTGAAACACTAA

Upstream 100 bases:

>100_bases
TGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTTGATGGTGCTGTTGAGCAATTACAAAAGA
TTGAGTTGGGATAAAATAGT

Downstream 100 bases:

>100_bases
AAAAGCCGAGTAAGGCTTTTTTTGCTATAATAGATGCAGTGACCATTATAAAAAAAGCAGTGCAAATGACACTGTCTTTT
CTTGAGATGGTATAGATGAC

Product: Undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRVNKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFG
QTYFSYILPVVIGATVITLTGFLDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLIAAIAGFFPYNYHPAMIYLGDTGALFIGFM
IGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAIIRRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSL
ISLLLNVSSRIGGVLLILGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH

Sequences:

>Translated_389_residues
MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRVNKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFG
QTYFSYILPVVIGATVITLTGFLDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLIAAIAGFFPYNYHPAMIYLGDTGALFIGFM
IGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAIIRRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSL
ISLLLNVSSRIGGVLLILGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH
>Mature_389_residues
MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRVNKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFG
QTYFSYILPVVIGATVITLTGFLDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLIAAIAGFFPYNYHPAMIYLGDTGALFIGFM
IGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAIIRRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSL
ISLLLNVSSRIGGVLLILGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=290, Percent_Identity=26.8965517241379, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 42858; Mature: 42858

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]