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The map label for this gene is mecA [H]

Identifier: 94993632

GI number: 94993632

Start: 247453

End: 248220

Strand: Direct

Name: mecA [H]

Synonym: MGAS10750_Spy0236

Alternate gene names: 94993632

Gene position: 247453-248220 (Clockwise)

Preceding gene: 94993631

Following gene: 94993633

Centisome position: 12.77

GC content: 35.94

Gene sequence:

>768_bases
TTGATAATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAAT
GGAGTTGAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAG
ATAATTTTAAAGATAGTGGTATGCTTAGTTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCT
GAGATAAATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAA
GAGCTTGGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAAAAAATTGAAGAGATAATGGAAG
ATGTTGTTGAAGCCACTCTAGCTAATCAGTCTGAAGCGGCTGATCCATCAACTAATCATGATTCAGAACCTTTAGACTAT
ATCCATTATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTC
AGAGTTATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAATG
TCATGTATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTG
ATGCTTGATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Upstream 100 bases:

>100_bases
ACTGTCGCTTTTTAAATTTCCTTTTGTAGAAGAGGAGTTAGTCATAAATTGCGAAATTACAGCATTTCTAGTATAATAAA
ATGACTACGCGTGCGAGGTA

Downstream 100 bases:

>100_bases
AATAGTATGTTTTCATTCACAATAGATTATGTCCTTGTTCTGATAGGGGCTTTGTTAATGTCCTTATTCTTAACCCCTCT
TGTTCGCTTTTTAGCCTTTC

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MIMEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKS
EINKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHDSEPLDY
IHYVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQL
MLDGAVEQLQKIELG

Sequences:

>Translated_255_residues
MIMEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKS
EINKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHDSEPLDY
IHYVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQL
MLDGAVEQLQKIELG
>Mature_255_residues
MIMEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKS
EINKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHDSEPLDY
IHYVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQL
MLDGAVEQLQKIELG

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis [H]

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 29296; Mature: 29296

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSG
CCCCHHHHCCEEEEEEEEECCHHHCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCC
MLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVK
EEEEEECCCCCCEEEEEEHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCH
AHEKLEKIEEIMEDVVEATLANQSEAADPSTNHDSEPLDYIHYVLDFSTITEAVAFAKTI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQL
CCCEEHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEE
MLDGAVEQLQKIELG
EEHHHHHHHHHHCCC
>Mature Secondary Structure
MIMEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSG
CCCCHHHHCCEEEEEEEEECCHHHCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCC
MLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVK
EEEEEECCCCCCEEEEEEHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCH
AHEKLEKIEEIMEDVVEATLANQSEAADPSTNHDSEPLDYIHYVLDFSTITEAVAFAKTI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQL
CCCEEHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEE
MLDGAVEQLQKIELG
EEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]