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The map label for this gene is yhfI [H]

Identifier: 94993569

GI number: 94993569

Start: 187474

End: 188253

Strand: Direct

Name: yhfI [H]

Synonym: MGAS10750_Spy0173

Alternate gene names: 94993569

Gene position: 187474-188253 (Clockwise)

Preceding gene: 94993568

Following gene: 94993570

Centisome position: 9.68

GC content: 43.59

Gene sequence:

>780_bases
ATGAAATTAACCACCTTAGGGTCTTGGGGAGCCTATCCCTATCAAGATGCAGGCACAACCTCTTATTTGGTCACAGGACA
TGACGGCTTTCAGTTATTGATGGATGCTGGTAGTCGAGCGCTCAATGAGCTGGAAAAAGAAATCAGTCCTCTCGATTTGG
ATGCAGTGATTATTAGCCATTACCATCCAGACCACGTGGCCGATTTAGGCGTGTTGCGCCATTATTTTCAACTTTATCCT
AAACACCTGTGGCAGCCTAAAGTATTGCCCATTTATGGGCATGATGAGGACCGACACGAATTTGCTAAGTTAAGCATTCC
TGATGTTTCAGAAGGTAGAGCCTATGATGTTACTGGAGTTGAACAGATTGGTCCTTTTGACATTACCTTTCTTAAAACAG
TTCATCCAGTTGTGTGTTATGCCTTTCGAATTGTAGAAAGAGCGACTGGTCAGGTACTTGTCTTTACTGGAGACAGTGGT
TATTTTGAAGGATTGGCAGACTTCGCAAAAGAAGCAGACCTTTTCTTAGCGGATGTTTACTTATACGAAGGCAATGAAAA
TCATATGGCCCATTTGACCAGTAAGGAAGCAGGACTAATGGCTAGCCAGGCAGGTGTTAAGAAGCTTGTCTTGACCCACA
TGCCACCGGTTCCTCCAGAAGGTATTAATTCCAAAAACCATTTAGAAGTGTTGAGGCAAGAAACACAGGCCTATGCAGGT
AATATTCCTGTTGACCTTGCCTTACCACACAAATCTTGGAACTTGGGGAGTCTTTCTTGA

Upstream 100 bases:

>100_bases
GGCAGATTTATCTGCTAGGACCTGTTTTTGGTGGGTCTCAATCCTCTTTGACACTAATTTTTGTTATAATAAGAGTTAAA
GCAAGAAAGAAGGGTTTGAG

Downstream 100 bases:

>100_bases
TGCCATATAGTTTAGAAGAGCAAACTTATTTCATGCAAGAGGCTTTAAAAGAAGCCGAAAAATCCTTACAGAAAGCTGAA
ATCCCCATTGGCTGTGTCAT

Product: Metal-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNELEKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYP
KHLWQPKVLPIYGHDEDRHEFAKLSIPDVSEGRAYDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVPPEGINSKNHLEVLRQETQAYAG
NIPVDLALPHKSWNLGSLS

Sequences:

>Translated_259_residues
MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNELEKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYP
KHLWQPKVLPIYGHDEDRHEFAKLSIPDVSEGRAYDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVPPEGINSKNHLEVLRQETQAYAG
NIPVDLALPHKSWNLGSLS
>Mature_259_residues
MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNELEKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYP
KHLWQPKVLPIYGHDEDRHEFAKLSIPDVSEGRAYDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVPPEGINSKNHLEVLRQETQAYAG
NIPVDLALPHKSWNLGSLS

Specific function: Unknown

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 28758; Mature: 28758

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNELEKEISPLDLDAVIISH
CEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
YHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHEFAKLSIPDVSEGRAYDVTGV
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHEEECCCCCCCCCEEECCCH
EQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSGYFEGLADFAKEADLFLADVY
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEEE
LYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVPPEGINSKNHLEVLRQETQAYAG
EEECCCCCEEEECCCHHCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCC
NIPVDLALPHKSWNLGSLS
CCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNELEKEISPLDLDAVIISH
CEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
YHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHEFAKLSIPDVSEGRAYDVTGV
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHEEECCCCCCCCCEEECCCH
EQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSGYFEGLADFAKEADLFLADVY
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEEE
LYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVPPEGINSKNHLEVLRQETQAYAG
EEECCCCCEEEECCCHHCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCC
NIPVDLALPHKSWNLGSLS
CCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]