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The map label for this gene is yusP [H]

Identifier: 94972141

GI number: 94972141

Start: 352636

End: 354690

Strand: Direct

Name: yusP [H]

Synonym: Dgeo_2674

Alternate gene names: 94972141

Gene position: 352636-354690 (Clockwise)

Preceding gene: 94972142

Following gene: 94972133

Centisome position: 61.42

GC content: 64.72

Gene sequence:

>2055_bases
ATGACCGCCTCTCCCTCGGCTACCCTGCCAGCGCCCACTTTCAACGACCAGGAGAAGCGCACCACCCTAATTGGCCTGCT
GGTGGTTTTTCTCCTCGCGGCGCTGAGCCAGACCATCGTCAGTACGGCCATGCCGCGCATCATCGCGGACCTCCAGGGCT
TTAACCTGTATTCTTGGGTCACCACCGCCTACCTGCTGGCCAGCACGGTGATGGTGCCGATCTACGGCAAGCTATCGGAC
CTCTATGGCCGCAAGCCGATCCTGGTGTTCGGCATCGTGGTCTTCCTTATCGGCTCGGCACTCAGCGGTTTGAGCGGCGA
ACCCTTCCTGGGGAACCTCCTCGGCGGCGGCATGAACCAGCTGATCGCCTTCCGCGCAGTGGCGGGCTTCGGGGGCGCCG
CGCTTTTCACGACGGCCTTTACCATCCTGGCCGACATGTTTGCCCCTGCGGAGCGCGCGAAGTTCGGCGGCCTCTTCGGC
GCCATTTTCGGCCTGGCCAGTGTGGTTGGTCCGGCGGTGGGCGGGTTCCTGACCGACAACCTCAGCTGGCGCTGGGTGTT
CTATGTGAACCTGCCGCTTGGCCTGCTGGCTCTCTTCCTGATTCTCGCCAAGATGCCCCGGCTGACCCACCGGGCAGAAG
GCCGCATTGACCTCCTGGGCGCGGCGCTTATTCTCTCAACTACCATTCCGCTGCTGCTGGCCCTCACTTGGGGCGGCACA
ACCTACCCCTGGGACAGCGCCCGCATCATCACCCTGTTTGCCGTGAGCGCCGTCAGCCTGATTGTCTTTTTGTTGGTGGA
GGCGCGCACCAAGGACGCCATTATCCCGCTCAGCCTCTTCCGGATCCGGATGTTCTCGCTGGGCAACCTGGCTGCCTTCA
TCATGGGAATGGCGTTCCTGGGTGTGATCCTGTTCCTGCCGCTGTACATGCAGATGGTGCTGGGCGTCTCCCCCACCAAG
AGCGGCTTCTCGATGCTGCCGCTGATGGGCGGCCTGATCCTCTCCAGCATCGGCGTCGGCCAGATTGTGGCCCGCACCGG
CAAGTACAAGCCCTGGATGATCGGCGGCGGCGTGATCCTGATGCTGGGCATCTTTTTCCTGACCAAAATCACCACCCACA
CCACCTTGGCGGACTTGGCCTGGCGAATGTTTGTCGTGGGTCTGGGCCTCGGCCCCTCGCAAAGCCTCTTTACGCTTGCC
ATCCAGAATGCCGTCCCGCTGAACCAGTTGGGGATTGCCACCTCCAGCTCGCAGTTCTTCCGCCAGATCGGCTCCACCAT
CGGCGCCGCCGTGTTCGGCACGCTGCTGCTGAACAATCTGCATACCGAGTTGCCCAAGCACCTGCCCCAGCTGCCCGGCA
TGCAGATGAACGCGAACAACTTCGATCTGGGCGCGCTGCGGGCGAGTGCAAACGGCAGCGGCAACGGCCCCGAGCAGAAG
ATTCAGGAAGCGTTGAATGCCCAGTACGCCCAGATCGAGCAGGCGCTGAACGGCGACGCGGCGGCGGCGCAGGCCATCGC
GGCCAACCCCGCCCTGCCGGCCGAACTCAAGGCGCTGGTGGCGAACGGTGGGATCCAAGCCCAGGTCCACCAGAAGCTGA
CGGCGCAGGCGACTCAGATTGCCAATGTGCTGAAAAACGGCGAGGCGGGCCGTCAGGCGCTGCTGAAGAGTCCCCAGACC
CCCGCCGCCCTCAAGACCCAGCTCCAGGCCCTCCCCGCGCAGGCCCTCGCGACGCCGCAGGCCGCCGCCGCGACCGCGCA
GCGGGTCAAGCAGGGCATCCTGGCGCAGGAACCCGCCGCCGTGCAGCAGGCCAAGCAGACAGTGCTGGCGCAGCTCAAGA
CGCGGCTGAACGAACAGGCCAAGACGCTCGCCGCACAGCTCACCAACGGCATGAAAGAAGGCTTTACCGCCGCCATGACC
CGCATGTTCGGGACGAGCATCTGGATCATCCTGGTGGGCTTCCTCGTCACGCTGTTTGTTCCGGCCATTCCGCTGCGGAA
CCAGATGGAGAAGGCGGCGCCCAGCACCCCGGCCACGCCGAATCCTGCCGACTGA

Upstream 100 bases:

>100_bases
CAATTCAGGCTCTCACTGGCGCGCGGCTCGCGCGGCTGGACACCCGGACCCTCAGCGGTCTGCTGGACGCCCTAGAGCTT
CTGGCACAGGAGGAGTCGGT

Downstream 100 bases:

>100_bases
GCGAACACACCTCAACCGTGGGCAATCCGGAAACGTGCCGGGTTGCCCCTGTTCGTTTCAGCGCCAGGCCCACAGCCTCA
CACTACGGTCACGGCTTCCA

Product: EmrB/QacA family drug resistance transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 684; Mature: 683

Protein sequence:

>684_residues
MTASPSATLPAPTFNDQEKRTTLIGLLVVFLLAALSQTIVSTAMPRIIADLQGFNLYSWVTTAYLLASTVMVPIYGKLSD
LYGRKPILVFGIVVFLIGSALSGLSGEPFLGNLLGGGMNQLIAFRAVAGFGGAALFTTAFTILADMFAPAERAKFGGLFG
AIFGLASVVGPAVGGFLTDNLSWRWVFYVNLPLGLLALFLILAKMPRLTHRAEGRIDLLGAALILSTTIPLLLALTWGGT
TYPWDSARIITLFAVSAVSLIVFLLVEARTKDAIIPLSLFRIRMFSLGNLAAFIMGMAFLGVILFLPLYMQMVLGVSPTK
SGFSMLPLMGGLILSSIGVGQIVARTGKYKPWMIGGGVILMLGIFFLTKITTHTTLADLAWRMFVVGLGLGPSQSLFTLA
IQNAVPLNQLGIATSSSQFFRQIGSTIGAAVFGTLLLNNLHTELPKHLPQLPGMQMNANNFDLGALRASANGSGNGPEQK
IQEALNAQYAQIEQALNGDAAAAQAIAANPALPAELKALVANGGIQAQVHQKLTAQATQIANVLKNGEAGRQALLKSPQT
PAALKTQLQALPAQALATPQAAAATAQRVKQGILAQEPAAVQQAKQTVLAQLKTRLNEQAKTLAAQLTNGMKEGFTAAMT
RMFGTSIWIILVGFLVTLFVPAIPLRNQMEKAAPSTPATPNPAD

Sequences:

>Translated_684_residues
MTASPSATLPAPTFNDQEKRTTLIGLLVVFLLAALSQTIVSTAMPRIIADLQGFNLYSWVTTAYLLASTVMVPIYGKLSD
LYGRKPILVFGIVVFLIGSALSGLSGEPFLGNLLGGGMNQLIAFRAVAGFGGAALFTTAFTILADMFAPAERAKFGGLFG
AIFGLASVVGPAVGGFLTDNLSWRWVFYVNLPLGLLALFLILAKMPRLTHRAEGRIDLLGAALILSTTIPLLLALTWGGT
TYPWDSARIITLFAVSAVSLIVFLLVEARTKDAIIPLSLFRIRMFSLGNLAAFIMGMAFLGVILFLPLYMQMVLGVSPTK
SGFSMLPLMGGLILSSIGVGQIVARTGKYKPWMIGGGVILMLGIFFLTKITTHTTLADLAWRMFVVGLGLGPSQSLFTLA
IQNAVPLNQLGIATSSSQFFRQIGSTIGAAVFGTLLLNNLHTELPKHLPQLPGMQMNANNFDLGALRASANGSGNGPEQK
IQEALNAQYAQIEQALNGDAAAAQAIAANPALPAELKALVANGGIQAQVHQKLTAQATQIANVLKNGEAGRQALLKSPQT
PAALKTQLQALPAQALATPQAAAATAQRVKQGILAQEPAAVQQAKQTVLAQLKTRLNEQAKTLAAQLTNGMKEGFTAAMT
RMFGTSIWIILVGFLVTLFVPAIPLRNQMEKAAPSTPATPNPAD
>Mature_683_residues
TASPSATLPAPTFNDQEKRTTLIGLLVVFLLAALSQTIVSTAMPRIIADLQGFNLYSWVTTAYLLASTVMVPIYGKLSDL
YGRKPILVFGIVVFLIGSALSGLSGEPFLGNLLGGGMNQLIAFRAVAGFGGAALFTTAFTILADMFAPAERAKFGGLFGA
IFGLASVVGPAVGGFLTDNLSWRWVFYVNLPLGLLALFLILAKMPRLTHRAEGRIDLLGAALILSTTIPLLLALTWGGTT
YPWDSARIITLFAVSAVSLIVFLLVEARTKDAIIPLSLFRIRMFSLGNLAAFIMGMAFLGVILFLPLYMQMVLGVSPTKS
GFSMLPLMGGLILSSIGVGQIVARTGKYKPWMIGGGVILMLGIFFLTKITTHTTLADLAWRMFVVGLGLGPSQSLFTLAI
QNAVPLNQLGIATSSSQFFRQIGSTIGAAVFGTLLLNNLHTELPKHLPQLPGMQMNANNFDLGALRASANGSGNGPEQKI
QEALNAQYAQIEQALNGDAAAAQAIAANPALPAELKALVANGGIQAQVHQKLTAQATQIANVLKNGEAGRQALLKSPQTP
AALKTQLQALPAQALATPQAAAATAQRVKQGILAQEPAAVQQAKQTVLAQLKTRLNEQAKTLAAQLTNGMKEGFTAAMTR
MFGTSIWIILVGFLVTLFVPAIPLRNQMEKAAPSTPATPNPAD

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=461, Percent_Identity=27.114967462039, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI87081983, Length=414, Percent_Identity=26.8115942028986, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1788710, Length=415, Percent_Identity=25.3012048192771, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1790195, Length=365, Percent_Identity=28.4931506849315, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788392, Length=321, Percent_Identity=32.7102803738318, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322958, Length=523, Percent_Identity=25.0478011472275, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6319783, Length=403, Percent_Identity=24.8138957816377, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6325455, Length=259, Percent_Identity=29.7297297297297, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319770, Length=448, Percent_Identity=26.7857142857143, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323735, Length=327, Percent_Identity=26.9113149847095, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6321663, Length=159, Percent_Identity=33.9622641509434, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24654039, Length=223, Percent_Identity=29.1479820627803, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24654037, Length=223, Percent_Identity=29.1479820627803, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17864456, Length=223, Percent_Identity=29.1479820627803, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24654041, Length=223, Percent_Identity=29.1479820627803, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24654044, Length=164, Percent_Identity=32.3170731707317, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 72217; Mature: 72086

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASPSATLPAPTFNDQEKRTTLIGLLVVFLLAALSQTIVSTAMPRIIADLQGFNLYSWV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TTAYLLASTVMVPIYGKLSDLYGRKPILVFGIVVFLIGSALSGLSGEPFLGNLLGGGMNQ
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHH
LIAFRAVAGFGGAALFTTAFTILADMFAPAERAKFGGLFGAIFGLASVVGPAVGGFLTDN
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC
LSWRWVFYVNLPLGLLALFLILAKMPRLTHRAEGRIDLLGAALILSTTIPLLLALTWGGT
CCEEEEEEEECCHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
TYPWDSARIITLFAVSAVSLIVFLLVEARTKDAIIPLSLFRIRMFSLGNLAAFIMGMAFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVILFLPLYMQMVLGVSPTKSGFSMLPLMGGLILSSIGVGQIVARTGKYKPWMIGGGVIL
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECCHHHH
MLGIFFLTKITTHTTLADLAWRMFVVGLGLGPSQSLFTLAIQNAVPLNQLGIATSSSQFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCCHHHHH
RQIGSTIGAAVFGTLLLNNLHTELPKHLPQLPGMQMNANNFDLGALRASANGSGNGPEQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHEEECCCCCCCCHHHH
IQEALNAQYAQIEQALNGDAAAAQAIAANPALPAELKALVANGGIQAQVHQKLTAQATQI
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ANVLKNGEAGRQALLKSPQTPAALKTQLQALPAQALATPQAAAATAQRVKQGILAQEPAA
HHHHHCCCHHHHHHHCCCCCCHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCHH
VQQAKQTVLAQLKTRLNEQAKTLAAQLTNGMKEGFTAAMTRMFGTSIWIILVGFLVTLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAIPLRNQMEKAAPSTPATPNPAD
CCCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TASPSATLPAPTFNDQEKRTTLIGLLVVFLLAALSQTIVSTAMPRIIADLQGFNLYSWV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TTAYLLASTVMVPIYGKLSDLYGRKPILVFGIVVFLIGSALSGLSGEPFLGNLLGGGMNQ
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHH
LIAFRAVAGFGGAALFTTAFTILADMFAPAERAKFGGLFGAIFGLASVVGPAVGGFLTDN
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC
LSWRWVFYVNLPLGLLALFLILAKMPRLTHRAEGRIDLLGAALILSTTIPLLLALTWGGT
CCEEEEEEEECCHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
TYPWDSARIITLFAVSAVSLIVFLLVEARTKDAIIPLSLFRIRMFSLGNLAAFIMGMAFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVILFLPLYMQMVLGVSPTKSGFSMLPLMGGLILSSIGVGQIVARTGKYKPWMIGGGVIL
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECCHHHH
MLGIFFLTKITTHTTLADLAWRMFVVGLGLGPSQSLFTLAIQNAVPLNQLGIATSSSQFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCCHHHHH
RQIGSTIGAAVFGTLLLNNLHTELPKHLPQLPGMQMNANNFDLGALRASANGSGNGPEQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHEEECCCCCCCCHHHH
IQEALNAQYAQIEQALNGDAAAAQAIAANPALPAELKALVANGGIQAQVHQKLTAQATQI
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ANVLKNGEAGRQALLKSPQTPAALKTQLQALPAQALATPQAAAATAQRVKQGILAQEPAA
HHHHHCCCHHHHHHHCCCCCCHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCHH
VQQAKQTVLAQLKTRLNEQAKTLAAQLTNGMKEGFTAAMTRMFGTSIWIILVGFLVTLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAIPLRNQMEKAAPSTPATPNPAD
CCCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]