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The map label for this gene is lutA [H]

Identifier: 94971920

GI number: 94971920

Start: 33648

End: 34391

Strand: Direct

Name: lutA [H]

Synonym: Dgeo_2452

Alternate gene names: 94971920

Gene position: 33648-34391 (Clockwise)

Preceding gene: 94971921

Following gene: 94971919

Centisome position: 5.86

GC content: 62.77

Gene sequence:

>744_bases
GTGAAGATCGATCTATTCATCACCTGCCTCAATGACGCGATGTTTCCCCGCACTGGGGAGGCGACGGTTCGGTTGTTGGA
GCGCCTCGGCCATGAGGTCCGCTTCGACGAGCGGCAGACCTGCTGCGGGCAGATGCACTTTAATTCGGGGTATCACCAAG
ACGCCCTCGGCTTGATCCGGCACTTTGTGAAGACCTTCCGGGATGCGGAGGTCGTGGTCGCGCCCAGCGGTTCCTGTGTG
GGGATGGTGCGCGATCTCTATCGCCGCGCCGCCGAGTGGGCGGGAGACGCGCGGCTGCTGGAGGAGGTGCAGGCGCTGGC
GCCCCGCGTCTTCGAGCTGAGCGAGTTTTTGGTGCAACGTCTGGGTGTTGAGGACGTCGGGGCGTACTATCCACACCGAG
TCACCTATCATCAGACCTGCCACGCGTTGCGGATTCTGCGTGTGGGCGAGGCGCCGTTGCGGCTGTTGCGGCATGTGCGC
GGCTTGACCCTGGTCGAGCTCCCCGCCATGGACCAATGCTGCGGGTTTGGCGGCACCTTTAGCGTGAAAAACGCCGACAC
CAGTACGGCCATGCTCGCGGATAAAGTGCAGAACGTGATGAGCACGGGGGCCGAAGCCTGCACTGCAGGAGACAACTCCT
GCCTGATGCACATTGGCGGCGGTCTCCACCGACTGCGCAGTGGCACCCGCACCATTCACCTGGCAGAAATTTTGGCCAGC
ACCGAAGAGGAGGTCTTCAGATGA

Upstream 100 bases:

>100_bases
TTGCGTCGTCCCCACCGCGTGCTGTCTTGAAACCGCACAGGGGGCTCCCGCCGTCACGTCCTGGCCTCAGCCTTTTTGAT
TTCTGCCCGAGGTATGCCCT

Downstream 100 bases:

>100_bases
GCGCCGGAGGCATCAAGCCTGCCCGGACTTTCCAGCAGGCCGCACGCAAGACCCTTGACAACCCGCAGATGCGCCGCAAC
CTCCGGCATGCCACCACCAC

Product: protein of unknown function DUF224, cysteine-rich region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKIDLFITCLNDAMFPRTGEATVRLLERLGHEVRFDERQTCCGQMHFNSGYHQDALGLIRHFVKTFRDAEVVVAPSGSCV
GMVRDLYRRAAEWAGDARLLEEVQALAPRVFELSEFLVQRLGVEDVGAYYPHRVTYHQTCHALRILRVGEAPLRLLRHVR
GLTLVELPAMDQCCGFGGTFSVKNADTSTAMLADKVQNVMSTGAEACTAGDNSCLMHIGGGLHRLRSGTRTIHLAEILAS
TEEEVFR

Sequences:

>Translated_247_residues
MKIDLFITCLNDAMFPRTGEATVRLLERLGHEVRFDERQTCCGQMHFNSGYHQDALGLIRHFVKTFRDAEVVVAPSGSCV
GMVRDLYRRAAEWAGDARLLEEVQALAPRVFELSEFLVQRLGVEDVGAYYPHRVTYHQTCHALRILRVGEAPLRLLRHVR
GLTLVELPAMDQCCGFGGTFSVKNADTSTAMLADKVQNVMSTGAEACTAGDNSCLMHIGGGLHRLRSGTRTIHLAEILAS
TEEEVFR
>Mature_247_residues
MKIDLFITCLNDAMFPRTGEATVRLLERLGHEVRFDERQTCCGQMHFNSGYHQDALGLIRHFVKTFRDAEVVVAPSGSCV
GMVRDLYRRAAEWAGDARLLEEVQALAPRVFELSEFLVQRLGVEDVGAYYPHRVTYHQTCHALRILRVGEAPLRLLRHVR
GLTLVELPAMDQCCGFGGTFSVKNADTSTAMLADKVQNVMSTGAEACTAGDNSCLMHIGGGLHRLRSGTRTIHLAEILAS
TEEEVFR

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lutA/ykgE family [H]

Homologues:

Organism=Escherichia coli, GI1786497, Length=244, Percent_Identity=39.7540983606557, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI48994913, Length=224, Percent_Identity=23.6607142857143, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004017
- InterPro:   IPR022822 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 27478; Mature: 27478

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDLFITCLNDAMFPRTGEATVRLLERLGHEVRFDERQTCCGQMHFNSGYHQDALGLIR
CCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
HFVKTFRDAEVVVAPSGSCVGMVRDLYRRAAEWAGDARLLEEVQALAPRVFELSEFLVQR
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGVEDVGAYYPHRVTYHQTCHALRILRVGEAPLRLLRHVRGLTLVELPAMDQCCGFGGTF
CCHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCHHHHHCCCCCE
SVKNADTSTAMLADKVQNVMSTGAEACTAGDNSCLMHIGGGLHRLRSGTRTIHLAEILAS
EECCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCHHHHHHHCCCCHHHHHHHHHH
TEEEVFR
HHHHHCC
>Mature Secondary Structure
MKIDLFITCLNDAMFPRTGEATVRLLERLGHEVRFDERQTCCGQMHFNSGYHQDALGLIR
CCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
HFVKTFRDAEVVVAPSGSCVGMVRDLYRRAAEWAGDARLLEEVQALAPRVFELSEFLVQR
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGVEDVGAYYPHRVTYHQTCHALRILRVGEAPLRLLRHVRGLTLVELPAMDQCCGFGGTF
CCHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCHHHHHCCCCCE
SVKNADTSTAMLADKVQNVMSTGAEACTAGDNSCLMHIGGGLHRLRSGTRTIHLAEILAS
EECCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCHHHHHHHCCCCHHHHHHHHHH
TEEEVFR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]