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The map label for this gene is paaK [H]

Identifier: 94971877

GI number: 94971877

Start: 78480

End: 79760

Strand: Direct

Name: paaK [H]

Synonym: Dgeo_2409

Alternate gene names: 94971877

Gene position: 78480-79760 (Clockwise)

Preceding gene: 94971878

Following gene: 94971873

Centisome position: 13.67

GC content: 67.76

Gene sequence:

>1281_bases
ATGTTTCAACCCGACTTTGAAGCGCTGCCCCTTTCCGACCTGCGCGCCCTGCAACTCGCGCGGCTGCAGGCGATGGTGGC
CCGCCAGTTTGAACATGTCCCCGCCTACCGCGCCAAGTTCGAGGCGGCAGGTGTCACGCCGGATGACCTGCGAACGTTGG
ACGACCTCGCCCGCTTTCCCATGACGCGCAAGAGTGACCTGCGAGACCACTATCCCCTGGGCTTGACCGCCGTCCCCCGC
CACGAGCTGCGCCGCCTGCATGCCAGCAGCGGCACCACCGGCAAACCCACGGTTGTCGCCTACGACGAGAACGATCTGGC
CGTGTTCGCGGAGGTGGTCGCGCGCTCGCTCTATGCGGCGGGTGCGCGGCCCGGCATGACCTTTCACAATGCCTACGGGT
ACGGCCTCTTCACGGGTGGGTTGGGGTTGCACGGCGGCGCCGAGCGGCTGGGCCTGAACACCGTGCCGGTGTCGGGGGGC
GGAACCGAGCGGCAGGTGGGCCTGATCCTCGACCTTCAGCCGGAGGTGATCGCCTGCACGCCCAGTTACGCGCTGGTGCT
GGCCGATGCCCTGGCGAAGCAGGGCCTGCGCCCAGAAGACCTCTCCCTGCGCTACGCCGTGCTGGGCGCCGAACCCTGGA
CCGAGAAGACCCGCCGCGAGGTGGAGGCCCGGTTGGGTGTCATCGCCACCAACATCTACGGCCTCTCCGAAATCATCGGC
CCCGGCGTCAGCAACGAGGACGCGACCGAACAGCAGGGCAGCTACGTCTGGGAAGACCACTTCTACCCCGAGATCGTCCA
TCCCGAAACCGGAGAGGTGCTGCCCGATGGCGAGTACGGCGTACTGGTGCTCTCGTCCATGACCAGAACGGCCATGCCGA
TTCTGCGCTACTGGACCGGTGACATCACCCGGCTGCTGCCGGAGGCCAACGCAACTGGGCGCACCTTCCGGCGGATGGAC
CAGATTCGCGGGCGCGCGGACGACCTGATCATTCTGCGCGGCGTGAACGTGTACCCGACGCAGCTGGAGGCCGTGCTGGT
GGGGATGGGGCAGGTGAGCCCGCACTACCACATCTTCCTGACCCGCACCGGCACCCGCGACGACCTGACGCTGCGGGTGG
AAACCGAAACAGAAAGTGCCGCGCTGCGGGACGAGATCGAGCGGCGAATCAAGGCCCAGGTCGGCGTGACGGTGCGCTGC
GAACTGTGTGGGCCCGGCAGCCTTCCCCGCAGCGAGGGCGGCAAGCTCAAGCGGGTGACGGACCTGCGCCCGCGGCATTG
A

Upstream 100 bases:

>100_bases
GACGTGATGCGGGACGTGAAGACCTTGTTTGATCCCCGCGGTTTGCTCAACCCCGGCAAGGTGGTGGGTGACCCCGAGAC
TCTGCCCTCATGGAGGAATG

Downstream 100 bases:

>100_bases
GGCTCAGATCGCCCTGGTCCGCCGCAGAAAGCGCGTGAGCAGCGCACCTGCCGCCGTGAACAGCCCCGCCGTTAGGCCCA
ACCACAGGCCACGCGGCCCC

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MFQPDFEALPLSDLRALQLARLQAMVARQFEHVPAYRAKFEAAGVTPDDLRTLDDLARFPMTRKSDLRDHYPLGLTAVPR
HELRRLHASSGTTGKPTVVAYDENDLAVFAEVVARSLYAAGARPGMTFHNAYGYGLFTGGLGLHGGAERLGLNTVPVSGG
GTERQVGLILDLQPEVIACTPSYALVLADALAKQGLRPEDLSLRYAVLGAEPWTEKTRREVEARLGVIATNIYGLSEIIG
PGVSNEDATEQQGSYVWEDHFYPEIVHPETGEVLPDGEYGVLVLSSMTRTAMPILRYWTGDITRLLPEANATGRTFRRMD
QIRGRADDLIILRGVNVYPTQLEAVLVGMGQVSPHYHIFLTRTGTRDDLTLRVETETESAALRDEIERRIKAQVGVTVRC
ELCGPGSLPRSEGGKLKRVTDLRPRH

Sequences:

>Translated_426_residues
MFQPDFEALPLSDLRALQLARLQAMVARQFEHVPAYRAKFEAAGVTPDDLRTLDDLARFPMTRKSDLRDHYPLGLTAVPR
HELRRLHASSGTTGKPTVVAYDENDLAVFAEVVARSLYAAGARPGMTFHNAYGYGLFTGGLGLHGGAERLGLNTVPVSGG
GTERQVGLILDLQPEVIACTPSYALVLADALAKQGLRPEDLSLRYAVLGAEPWTEKTRREVEARLGVIATNIYGLSEIIG
PGVSNEDATEQQGSYVWEDHFYPEIVHPETGEVLPDGEYGVLVLSSMTRTAMPILRYWTGDITRLLPEANATGRTFRRMD
QIRGRADDLIILRGVNVYPTQLEAVLVGMGQVSPHYHIFLTRTGTRDDLTLRVETETESAALRDEIERRIKAQVGVTVRC
ELCGPGSLPRSEGGKLKRVTDLRPRH
>Mature_426_residues
MFQPDFEALPLSDLRALQLARLQAMVARQFEHVPAYRAKFEAAGVTPDDLRTLDDLARFPMTRKSDLRDHYPLGLTAVPR
HELRRLHASSGTTGKPTVVAYDENDLAVFAEVVARSLYAAGARPGMTFHNAYGYGLFTGGLGLHGGAERLGLNTVPVSGG
GTERQVGLILDLQPEVIACTPSYALVLADALAKQGLRPEDLSLRYAVLGAEPWTEKTRREVEARLGVIATNIYGLSEIIG
PGVSNEDATEQQGSYVWEDHFYPEIVHPETGEVLPDGEYGVLVLSSMTRTAMPILRYWTGDITRLLPEANATGRTFRRMD
QIRGRADDLIILRGVNVYPTQLEAVLVGMGQVSPHYHIFLTRTGTRDDLTLRVETETESAALRDEIERRIKAQVGVTVRC
ELCGPGSLPRSEGGKLKRVTDLRPRH

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=427, Percent_Identity=51.5222482435597, Blast_Score=428, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 46951; Mature: 46951

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQPDFEALPLSDLRALQLARLQAMVARQFEHVPAYRAKFEAAGVTPDDLRTLDDLARFP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCHHHHHHHHHHHHCC
MTRKSDLRDHYPLGLTAVPRHELRRLHASSGTTGKPTVVAYDENDLAVFAEVVARSLYAA
CCCCCCCCCCCCCCCEECCHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHC
GARPGMTFHNAYGYGLFTGGLGLHGGAERLGLNTVPVSGGGTERQVGLILDLQPEVIACT
CCCCCCEEECCCCCEEEECCCCCCCCHHHCCCEEEECCCCCCCCEEEEEEECCCCEEEEC
PSYALVLADALAKQGLRPEDLSLRYAVLGAEPWTEKTRREVEARLGVIATNIYGLSEIIG
CCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGVSNEDATEQQGSYVWEDHFYPEIVHPETGEVLPDGEYGVLVLSSMTRTAMPILRYWTG
CCCCCCCCHHHCCCEEECCCCCCEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
DITRLLPEANATGRTFRRMDQIRGRADDLIILRGVNVYPTQLEAVLVGMGQVSPHYHIFL
HHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHEEEEEECCCCCCCEEEEE
TRTGTRDDLTLRVETETESAALRDEIERRIKAQVGVTVRCELCGPGSLPRSEGGKLKRVT
EECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCEEEEC
DLRPRH
CCCCCC
>Mature Secondary Structure
MFQPDFEALPLSDLRALQLARLQAMVARQFEHVPAYRAKFEAAGVTPDDLRTLDDLARFP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCHHHHHHHHHHHHCC
MTRKSDLRDHYPLGLTAVPRHELRRLHASSGTTGKPTVVAYDENDLAVFAEVVARSLYAA
CCCCCCCCCCCCCCCEECCHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHC
GARPGMTFHNAYGYGLFTGGLGLHGGAERLGLNTVPVSGGGTERQVGLILDLQPEVIACT
CCCCCCEEECCCCCEEEECCCCCCCCHHHCCCEEEECCCCCCCCEEEEEEECCCCEEEEC
PSYALVLADALAKQGLRPEDLSLRYAVLGAEPWTEKTRREVEARLGVIATNIYGLSEIIG
CCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGVSNEDATEQQGSYVWEDHFYPEIVHPETGEVLPDGEYGVLVLSSMTRTAMPILRYWTG
CCCCCCCCHHHCCCEEECCCCCCEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
DITRLLPEANATGRTFRRMDQIRGRADDLIILRGVNVYPTQLEAVLVGMGQVSPHYHIFL
HHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHEEEEEECCCCCCCEEEEE
TRTGTRDDLTLRVETETESAALRDEIERRIKAQVGVTVRCELCGPGSLPRSEGGKLKRVT
EECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCEEEEC
DLRPRH
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]