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The map label for this gene is fadE25 [H]

Identifier: 94971873

GI number: 94971873

Start: 82872

End: 84668

Strand: Direct

Name: fadE25 [H]

Synonym: Dgeo_2405

Alternate gene names: 94971873

Gene position: 82872-84668 (Clockwise)

Preceding gene: 94971877

Following gene: 94971872

Centisome position: 14.43

GC content: 66.61

Gene sequence:

>1797_bases
ATGGCCCCCTTTCTCTCCCGCCGCGACCTGCAATTCCAGCTCTACGAGGTGCTGGACACTGCCTCCCTTCCGCAGCGCCC
GCGCTTTGCAGAACACAGCCGCGAGGTGTACGACGACGTGCTGAATCTCGCGTACACCATCGCCGAGAGGTACTTTGCCA
ACCACGCCCGCGAGGCGGACCTGAACGAGCCGCAGGTGGTGGACGGCAAGGTGAAGCTCGTTCCGGCTGCTGCCGAAGCC
ATGAGAGCCTTCCGCGAGGCCGGGTTTTTCAGCGCCCACGCCGACGAGGAGCTGGGCGGCCTACAACTCCCCCACGTGGT
CGCGCAGGCGGCGCACGCGCACTTCAAGGCCGCCAACATCGGCACGAGCAGTTATCCCTTCCTCACCATCGGGAACGCCA
ACCTGCAACGGGTGTTTGCCTCGCCCGAGCAGCAGCGCAAATACATGCTCCCCCTGCTGGAAGGCCGCTGGTTCGGCACG
ATGGCCCTCTCCGAGCCACACGCGGGGTCGGGCCTGGCGGACATCACCACCACCGCCACGCCGCGCGGCGACGGCACCTA
CAGCATCACCGGAACCAAGATGTGGATCTCGGCGGGCGAACACGAACTCTCAGAGAACATCATCCACCTCGTCCTGGCGC
GGATCAAGGGTGCCCCAGCAGGGGTGAAGGGCATCTCCCTCTTCATCGTGCCCCGGTACCGGGTGAACGCGGACGGCAGC
CTCGGTGAATCGAACAACGTCGTGCTGGCGGGGCTCAATCACAAGATGGGCTACCGGGGCACCACGAACACGCTGCTGAA
TTTCGGGGAGGGCGGCGAGACGATCGGGGAGCTGATCGGGGAGCCGGGCCGCGGCCTGGGGTACATGTTCCACATGATGA
ACAGCGCCCGCATCGGCGTCGGCATGGGCGCGGTGATGTTGGGCTACGCGGGCTACCTTGCCAGTCTGGAGTACGCCCGC
GAGCGGCGGCAGGGGCGGCACGCGAGCAACAAGGATCCGGAGAGCGAGCCTGTGCGCATCATCGAACACGCGGATGTGCG
CCGTCTCCTGCTGCGGCAGAAGAGCATCGTGGAAGGGGGCCTGGCGCTGGGCCTCTACGCCGCGCATCTCGAAGACGAGA
TCGAAACCGGCCCGGCAGAGGAACGCGAGGACAACGTGCTGCTCCTCGACCTGCTGACACCCATCGTGAAGAGCTGGCCC
AGCCGCTACAGCCAGGAAGCCCTCAGCGACGCGATTCAGGTGATGGGCGGGGCCGGGTACACCCGCGACTATCCGGTGGA
GATGTACTACCGCGACAACCGCCTCAACCCCATTCACGAGGGCACCGAAGGCATCCAGGGCAACGATCTGCTGGGCCGCA
AGGTCACGCAGGCGGGCGGACGGGGGCTGCACGTGCTGCTCGAACGGATTCAGACCGACCTGCAGGCGTCGGAGGGGCTT
GCAGGGTTGGCCGAGATCCGTGCGGCCCTGGAGCGGGCCGTCACCCAGAGCGCGGCAGCCCTGCAAGCCATCCTCAGCAA
AGCGCCCGAACTCGGCCCCGACCTTTTTCTCGCCAACGCGAACAGCGCCCTGGAAATGCTGGGGCATACTGTGATCGGCT
GGATGTGGTTGCGGCAGGCGGCGGCAGCGGCCCGCAGGCTCCCCGAGGCGCGCGGCGACGACGCCGACTTCTACCGGGGC
AAGGAGCAGGCCGCCCGTTTCTTCGCCACCCACGAGTTGCCGAAGGTGAAGGCCCACGCCGATTTGCTGGCGAGCGCGGA
CCGAACGACTTTTGAGATGCAGGACGCGTGGTTTTGA

Upstream 100 bases:

>100_bases
CGTCCTGGCCGTCCTCACGCTGTTCACGCCGCCGCGCCGGCCCTCGGCTCGCGGCTGGTCCCGCACGCCCGCGCCTGATT
CCCTGTAAGGAGACTTTCCT

Downstream 100 bases:

>100_bases
TGACCGGGTCAGCCGCAGCTGTCCGGCGGGTGAGCATTGGGGATCGAGTCCTCGCCTACACCGAGGTTTCACCGCCCCAT
CCCCGTGCGAACGTGCTGTT

Product: acyl-CoA dehydrogenase-like

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MAPFLSRRDLQFQLYEVLDTASLPQRPRFAEHSREVYDDVLNLAYTIAERYFANHAREADLNEPQVVDGKVKLVPAAAEA
MRAFREAGFFSAHADEELGGLQLPHVVAQAAHAHFKAANIGTSSYPFLTIGNANLQRVFASPEQQRKYMLPLLEGRWFGT
MALSEPHAGSGLADITTTATPRGDGTYSITGTKMWISAGEHELSENIIHLVLARIKGAPAGVKGISLFIVPRYRVNADGS
LGESNNVVLAGLNHKMGYRGTTNTLLNFGEGGETIGELIGEPGRGLGYMFHMMNSARIGVGMGAVMLGYAGYLASLEYAR
ERRQGRHASNKDPESEPVRIIEHADVRRLLLRQKSIVEGGLALGLYAAHLEDEIETGPAEEREDNVLLLDLLTPIVKSWP
SRYSQEALSDAIQVMGGAGYTRDYPVEMYYRDNRLNPIHEGTEGIQGNDLLGRKVTQAGGRGLHVLLERIQTDLQASEGL
AGLAEIRAALERAVTQSAAALQAILSKAPELGPDLFLANANSALEMLGHTVIGWMWLRQAAAAARRLPEARGDDADFYRG
KEQAARFFATHELPKVKAHADLLASADRTTFEMQDAWF

Sequences:

>Translated_598_residues
MAPFLSRRDLQFQLYEVLDTASLPQRPRFAEHSREVYDDVLNLAYTIAERYFANHAREADLNEPQVVDGKVKLVPAAAEA
MRAFREAGFFSAHADEELGGLQLPHVVAQAAHAHFKAANIGTSSYPFLTIGNANLQRVFASPEQQRKYMLPLLEGRWFGT
MALSEPHAGSGLADITTTATPRGDGTYSITGTKMWISAGEHELSENIIHLVLARIKGAPAGVKGISLFIVPRYRVNADGS
LGESNNVVLAGLNHKMGYRGTTNTLLNFGEGGETIGELIGEPGRGLGYMFHMMNSARIGVGMGAVMLGYAGYLASLEYAR
ERRQGRHASNKDPESEPVRIIEHADVRRLLLRQKSIVEGGLALGLYAAHLEDEIETGPAEEREDNVLLLDLLTPIVKSWP
SRYSQEALSDAIQVMGGAGYTRDYPVEMYYRDNRLNPIHEGTEGIQGNDLLGRKVTQAGGRGLHVLLERIQTDLQASEGL
AGLAEIRAALERAVTQSAAALQAILSKAPELGPDLFLANANSALEMLGHTVIGWMWLRQAAAAARRLPEARGDDADFYRG
KEQAARFFATHELPKVKAHADLLASADRTTFEMQDAWF
>Mature_597_residues
APFLSRRDLQFQLYEVLDTASLPQRPRFAEHSREVYDDVLNLAYTIAERYFANHAREADLNEPQVVDGKVKLVPAAAEAM
RAFREAGFFSAHADEELGGLQLPHVVAQAAHAHFKAANIGTSSYPFLTIGNANLQRVFASPEQQRKYMLPLLEGRWFGTM
ALSEPHAGSGLADITTTATPRGDGTYSITGTKMWISAGEHELSENIIHLVLARIKGAPAGVKGISLFIVPRYRVNADGSL
GESNNVVLAGLNHKMGYRGTTNTLLNFGEGGETIGELIGEPGRGLGYMFHMMNSARIGVGMGAVMLGYAGYLASLEYARE
RRQGRHASNKDPESEPVRIIEHADVRRLLLRQKSIVEGGLALGLYAAHLEDEIETGPAEEREDNVLLLDLLTPIVKSWPS
RYSQEALSDAIQVMGGAGYTRDYPVEMYYRDNRLNPIHEGTEGIQGNDLLGRKVTQAGGRGLHVLLERIQTDLQASEGLA
GLAEIRAALERAVTQSAAALQAILSKAPELGPDLFLANANSALEMLGHTVIGWMWLRQAAAAARRLPEARGDDADFYRGK
EQAARFFATHELPKVKAHADLLASADRTTFEMQDAWF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=337, Percent_Identity=28.1899109792285, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI4557233, Length=438, Percent_Identity=25.7990867579909, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI7656849, Length=422, Percent_Identity=26.0663507109005, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI4557235, Length=389, Percent_Identity=25.1928020565553, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI76496475, Length=389, Percent_Identity=25.1928020565553, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI87082384, Length=300, Percent_Identity=28, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17508101, Length=364, Percent_Identity=27.1978021978022, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17506239, Length=412, Percent_Identity=25.2427184466019, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17533517, Length=383, Percent_Identity=25.8485639686684, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=307, Percent_Identity=27.0358306188925, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=368, Percent_Identity=26.9021739130435, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=368, Percent_Identity=26.9021739130435, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=182, Percent_Identity=31.8681318681319, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666513, Length=370, Percent_Identity=27.8378378378378, Blast_Score=109, Evalue=6e-24,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=27.1276595744681, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=27.0053475935829, Blast_Score=100, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 65452; Mature: 65321

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPFLSRRDLQFQLYEVLDTASLPQRPRFAEHSREVYDDVLNLAYTIAERYFANHAREAD
CCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LNEPQVVDGKVKLVPAAAEAMRAFREAGFFSAHADEELGGLQLPHVVAQAAHAHFKAANI
CCCCCEECCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
GTSSYPFLTIGNANLQRVFASPEQQRKYMLPLLEGRWFGTMALSEPHAGSGLADITTTAT
CCCCCCEEEECCCCHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEECCC
PRGDGTYSITGTKMWISAGEHELSENIIHLVLARIKGAPAGVKGISLFIVPRYRVNADGS
CCCCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCC
LGESNNVVLAGLNHKMGYRGTTNTLLNFGEGGETIGELIGEPGRGLGYMFHMMNSARIGV
CCCCCCEEEEECCCCCCCCCCCHHHEECCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCC
GMGAVMLGYAGYLASLEYARERRQGRHASNKDPESEPVRIIEHADVRRLLLRQKSIVEGG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
LALGLYAAHLEDEIETGPAEEREDNVLLLDLLTPIVKSWPSRYSQEALSDAIQVMGGAGY
HHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TRDYPVEMYYRDNRLNPIHEGTEGIQGNDLLGRKVTQAGGRGLHVLLERIQTDLQASEGL
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
AGLAEIRAALERAVTQSAAALQAILSKAPELGPDLFLANANSALEMLGHTVIGWMWLRQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
AAAARRLPEARGDDADFYRGKEQAARFFATHELPKVKAHADLLASADRTTFEMQDAWF
HHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure 
APFLSRRDLQFQLYEVLDTASLPQRPRFAEHSREVYDDVLNLAYTIAERYFANHAREAD
CCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LNEPQVVDGKVKLVPAAAEAMRAFREAGFFSAHADEELGGLQLPHVVAQAAHAHFKAANI
CCCCCEECCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
GTSSYPFLTIGNANLQRVFASPEQQRKYMLPLLEGRWFGTMALSEPHAGSGLADITTTAT
CCCCCCEEEECCCCHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEECCC
PRGDGTYSITGTKMWISAGEHELSENIIHLVLARIKGAPAGVKGISLFIVPRYRVNADGS
CCCCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCC
LGESNNVVLAGLNHKMGYRGTTNTLLNFGEGGETIGELIGEPGRGLGYMFHMMNSARIGV
CCCCCCEEEEECCCCCCCCCCCHHHEECCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCC
GMGAVMLGYAGYLASLEYARERRQGRHASNKDPESEPVRIIEHADVRRLLLRQKSIVEGG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
LALGLYAAHLEDEIETGPAEEREDNVLLLDLLTPIVKSWPSRYSQEALSDAIQVMGGAGY
HHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TRDYPVEMYYRDNRLNPIHEGTEGIQGNDLLGRKVTQAGGRGLHVLLERIQTDLQASEGL
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
AGLAEIRAALERAVTQSAAALQAILSKAPELGPDLFLANANSALEMLGHTVIGWMWLRQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
AAAARRLPEARGDDADFYRGKEQAARFFATHELPKVKAHADLLASADRTTFEMQDAWF
HHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]