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The map label for this gene is cbiX [H]

Identifier: 94971829

GI number: 94971829

Start: 128609

End: 130171

Strand: Direct

Name: cbiX [H]

Synonym: Dgeo_2360

Alternate gene names: 94971829

Gene position: 128609-130171 (Clockwise)

Preceding gene: 94971830

Following gene: 94971828

Centisome position: 22.4

GC content: 70.25

Gene sequence:

>1563_bases
ATGAGCGGCTATGCCATCTTGCTCGCTGCCCACGGGAGCCGTGACCCTGCGAGCGCCGCGCAGTTTGGGGAGCTCGTGGC
GCAGGTCAAGGCGTTGGAACCGGGGCGCCTCATCACCCACGGCTTTCTGGAATTCAACACGCCCACCATCGCGCAGGCGG
CGCAGGCGGCGATCGCGGCGGGCGCACGCGAGATCGTGCTGGTCCCGGGCGTGTTGCTGGCGGCCACCCACGCCAAAAAT
GACCTTCCCAGCGAGCTGAATGCGCTGCGCCGGGCGTTTCCGCAGGTCACCTTCCACTGCGGCGCGGCGCTCGACCTGCA
CCCTGCACTCCTGGAAGTCTGCCGCGAGCGCCTGCTGGAGGCCGAGGTCGCCGCCGGGCGCGAGGTGCGCCGGGACGAGA
CGCTGCTGCTGCTCGTCGGGCGCGGAACCACCGACCCTGACGCCAACGGCGATGTCCACAAGCTGGCCCGCTTTCTGGAG
GAGGGCCTGGGCTACGGGGCCAGCCTGGTGTGTTACAGCGGCACGGCGAAGCCCGACCTGCCCACCGGCCTGGCCCGTGC
TGCCCGCCTGGGTTTTGCGCGGGTGGTGGTGCTGCCCTACCTGCTGTTTGACGGTGTGCTGGTCCGCCGGGTGCGGGAGG
CGGTGGCCGCCGCTGCCCAGCGCTGGCCGGACACCGAGTTTCTCAGCGCTGGGCACCTGGGGCCGCATCCCAAGGTCGCG
CAGGTGTTTTTGGAGCGGGCGCAGGAGGGCGTGCGGGGACAGGGCCACATGAACTGCTCGCTGTGCAAGTACCGCGTGGC
GGTGGTGGGCTATGAGGCGCAGGTGGGACAGCCTCAGGTGGGCCACCACGGGGCGGTGCGCGGTCTGCTCGCTGGGGGCA
CGGTTCCAGAGCGCCAGGGCATCCCGCCCTACGAGCCGCATCCCATCGAGCGGCAGTCCTTTGAGATCATCGAGTCGCTG
CGCGACTGGTCCGCCGTGCCGCCCGCTGACCGCTCCGTGATGCAGCGCCTCGTGCACACGGCGGGCACTCCGGAGATTGT
GGACGACCTGTATTTCTCGCCCGGTGCGGTAGAAGCGGGCGTGACGGCCATCCTGCGCGGCCTGACCGTTGTGACGGACG
TGACGATGGTGCAAAGCGGCCTGAAGCGTGAGGTGCTGCGGACGCTGGGGGTGCCGGTGTGGTGCGGCGTACACGATCCC
GAAACCCACCTGCTGAGCCGCGAGACGGGCCTCACCCGCTCGGCTGCCGGCATCCGGCGCGCTTTTGAAAAGTTCGGCAA
CGACTGCATCGTCGCCATTGGGGACGCGCCCACCGCGATTTTCGAGGCGGTGCGGCTGATCGAAGAGCGGCACTGGCGGC
CCGGGCTGGTGATCGGCCTGCCCGTCGGCTTTGTGGGCACCCGCGAGAGCAAGGCGGCCCTGAGGGCCTGTTTGCGGGTG
CCGCGCATCACCAACGCGGGCACGCGCGGGGGCAGCCCCTGGGCCAGCAGCGTGGTGAATGCCCTGATGATCGAGGCGCA
AAATCGCCTGGCTGCCGTCAGCGCCGCTGGGGCAGGCGCGTGA

Upstream 100 bases:

>100_bases
GGGGGACCCTGGGCGACCTGGAGGGCCGCGCGTTCTCCGACATGAGTATCCTGCTGATCCGTGCGCTCACGCCGCTGCCG
ACCGGCCTGGAGGGTGAGGC

Downstream 100 bases:

>100_bases
GCCTCGCCGTGATGCCCACCCGATTGGACCTCAGCCTGCCCGCCGCCAATGGCCTGCGCCGGGGCTTCACAACGGGCAGC
GCCGCCACTGCCGCGCTGAA

Product: precorrin-8X methylmutase CbiC/CobH

Products: NA

Alternate protein names: CbiXL [H]

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MSGYAILLAAHGSRDPASAAQFGELVAQVKALEPGRLITHGFLEFNTPTIAQAAQAAIAAGAREIVLVPGVLLAATHAKN
DLPSELNALRRAFPQVTFHCGAALDLHPALLEVCRERLLEAEVAAGREVRRDETLLLLVGRGTTDPDANGDVHKLARFLE
EGLGYGASLVCYSGTAKPDLPTGLARAARLGFARVVVLPYLLFDGVLVRRVREAVAAAAQRWPDTEFLSAGHLGPHPKVA
QVFLERAQEGVRGQGHMNCSLCKYRVAVVGYEAQVGQPQVGHHGAVRGLLAGGTVPERQGIPPYEPHPIERQSFEIIESL
RDWSAVPPADRSVMQRLVHTAGTPEIVDDLYFSPGAVEAGVTAILRGLTVVTDVTMVQSGLKREVLRTLGVPVWCGVHDP
ETHLLSRETGLTRSAAGIRRAFEKFGNDCIVAIGDAPTAIFEAVRLIEERHWRPGLVIGLPVGFVGTRESKAALRACLRV
PRITNAGTRGGSPWASSVVNALMIEAQNRLAAVSAAGAGA

Sequences:

>Translated_520_residues
MSGYAILLAAHGSRDPASAAQFGELVAQVKALEPGRLITHGFLEFNTPTIAQAAQAAIAAGAREIVLVPGVLLAATHAKN
DLPSELNALRRAFPQVTFHCGAALDLHPALLEVCRERLLEAEVAAGREVRRDETLLLLVGRGTTDPDANGDVHKLARFLE
EGLGYGASLVCYSGTAKPDLPTGLARAARLGFARVVVLPYLLFDGVLVRRVREAVAAAAQRWPDTEFLSAGHLGPHPKVA
QVFLERAQEGVRGQGHMNCSLCKYRVAVVGYEAQVGQPQVGHHGAVRGLLAGGTVPERQGIPPYEPHPIERQSFEIIESL
RDWSAVPPADRSVMQRLVHTAGTPEIVDDLYFSPGAVEAGVTAILRGLTVVTDVTMVQSGLKREVLRTLGVPVWCGVHDP
ETHLLSRETGLTRSAAGIRRAFEKFGNDCIVAIGDAPTAIFEAVRLIEERHWRPGLVIGLPVGFVGTRESKAALRACLRV
PRITNAGTRGGSPWASSVVNALMIEAQNRLAAVSAAGAGA
>Mature_519_residues
SGYAILLAAHGSRDPASAAQFGELVAQVKALEPGRLITHGFLEFNTPTIAQAAQAAIAAGAREIVLVPGVLLAATHAKND
LPSELNALRRAFPQVTFHCGAALDLHPALLEVCRERLLEAEVAAGREVRRDETLLLLVGRGTTDPDANGDVHKLARFLEE
GLGYGASLVCYSGTAKPDLPTGLARAARLGFARVVVLPYLLFDGVLVRRVREAVAAAAQRWPDTEFLSAGHLGPHPKVAQ
VFLERAQEGVRGQGHMNCSLCKYRVAVVGYEAQVGQPQVGHHGAVRGLLAGGTVPERQGIPPYEPHPIERQSFEIIESLR
DWSAVPPADRSVMQRLVHTAGTPEIVDDLYFSPGAVEAGVTAILRGLTVVTDVTMVQSGLKREVLRTLGVPVWCGVHDPE
THLLSRETGLTRSAAGIRRAFEKFGNDCIVAIGDAPTAIFEAVRLIEERHWRPGLVIGLPVGFVGTRESKAALRACLRVP
RITNAGTRGGSPWASSVVNALMIEAQNRLAAVSAAGAGA

Specific function: Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiX family. CbiXL subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002762 [H]

Pfam domain/function: PF01903 CbiX [H]

EC number: =4.99.1.3 [H]

Molecular weight: Translated: 55356; Mature: 55225

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGYAILLAAHGSRDPASAAQFGELVAQVKALEPGRLITHGFLEFNTPTIAQAAQAAIAA
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEECEEECCCCHHHHHHHHHHHC
GAREIVLVPGVLLAATHAKNDLPSELNALRRAFPQVTFHCGAALDLHPALLEVCRERLLE
CCCEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHH
AEVAAGREVRRDETLLLLVGRGTTDPDANGDVHKLARFLEEGLGYGASLVCYSGTAKPDL
HHHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCC
PTGLARAARLGFARVVVLPYLLFDGVLVRRVREAVAAAAQRWPDTEFLSAGHLGPHPKVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHH
QVFLERAQEGVRGQGHMNCSLCKYRVAVVGYEAQVGQPQVGHHGAVRGLLAGGTVPERQG
HHHHHHHHHCCCCCCCCCHHHHHEEEHEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCC
IPPYEPHPIERQSFEIIESLRDWSAVPPADRSVMQRLVHTAGTPEIVDDLYFSPGAVEAG
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCHHHH
VTAILRGLTVVTDVTMVQSGLKREVLRTLGVPVWCGVHDPETHLLSRETGLTRSAAGIRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHCCCCHHHHHHHH
AFEKFGNDCIVAIGDAPTAIFEAVRLIEERHWRPGLVIGLPVGFVGTRESKAALRACLRV
HHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHC
PRITNAGTRGGSPWASSVVNALMIEAQNRLAAVSAAGAGA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGYAILLAAHGSRDPASAAQFGELVAQVKALEPGRLITHGFLEFNTPTIAQAAQAAIAA
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEECEEECCCCHHHHHHHHHHHC
GAREIVLVPGVLLAATHAKNDLPSELNALRRAFPQVTFHCGAALDLHPALLEVCRERLLE
CCCEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHH
AEVAAGREVRRDETLLLLVGRGTTDPDANGDVHKLARFLEEGLGYGASLVCYSGTAKPDL
HHHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCC
PTGLARAARLGFARVVVLPYLLFDGVLVRRVREAVAAAAQRWPDTEFLSAGHLGPHPKVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHH
QVFLERAQEGVRGQGHMNCSLCKYRVAVVGYEAQVGQPQVGHHGAVRGLLAGGTVPERQG
HHHHHHHHHCCCCCCCCCHHHHHEEEHEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCC
IPPYEPHPIERQSFEIIESLRDWSAVPPADRSVMQRLVHTAGTPEIVDDLYFSPGAVEAG
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCHHHH
VTAILRGLTVVTDVTMVQSGLKREVLRTLGVPVWCGVHDPETHLLSRETGLTRSAAGIRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHCCCCHHHHHHHH
AFEKFGNDCIVAIGDAPTAIFEAVRLIEERHWRPGLVIGLPVGFVGTRESKAALRACLRV
HHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHC
PRITNAGTRGGSPWASSVVNALMIEAQNRLAAVSAAGAGA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9742225; 12917443 [H]