Click here to switch to the map view.

The map label for this gene is 94971830

Identifier: 94971830

GI number: 94971830

Start: 127926

End: 128612

Strand: Direct

Name: 94971830

Synonym: Dgeo_2361

Alternate gene names: NA

Gene position: 127926-128612 (Clockwise)

Preceding gene: 94971831

Following gene: 94971829

Centisome position: 22.28

GC content: 65.65

Gene sequence:

>687_bases
ATGATTGTCTGTGTTGGTGCTGGCCCTGGGCACCTGGATTTTCTGACGCGGCGGGGCGCAGAACTGGTCTCTAACGCCGA
TGTGGTGGCGGGCTTTGCCGCTGTGGTCGATGTGGTGCGGCCCCTGCTGCTCGCCGACCAACAGGTCGTCACGATGGGTT
ACCGCGATCAGGTGGCGAAACTCGCGGAGGTGGCCGCGCTGCACCACGCCGGGAAAAACTGCGTGGTGGTGTTTATGGGG
GACATCCACTTCAGCGGCTTTCAATTTCTCGAGCGGGTGGAGACAGCCTGTGGTCACCCGGTAGAGACGGTGCCGGGCAT
TTCGAGCGCGCAGCTGCTCGCCAGCCGGGGCCGCGTTTGTTTTGACGAGACGACCTTTCTCACCTTTCACCGCCGAGGCG
ACCTGACCCCTTTCAAGACCCACCTACGCGACGTGCTGCGGGCCGGAAGAAACGCCATCGTGATTCCGCGTCCCTGGGAC
TTTATGCCGGGGGACGTGGCGGCCTACCTGCTCGCCCACGGTGCAAGTCCCGCGCACCGGGCGGAGGTCTGGGAAAACCT
CTCCCGCGACGAGGCCGCGTGGCGGGGGACCCTGGGCGACCTGGAGGGCCGCGCGTTCTCCGACATGAGTATCCTGCTGA
TCCGTGCGCTCACGCCGCTGCCGACCGGCCTGGAGGGTGAGGCATGA

Upstream 100 bases:

>100_bases
GTCGCGCTGGCCGACACGGTGAGCGAGATTCAGCCCGTCAAGCACGCCTACGCGGCGGGCATCGGTGCGCAGGCTGGGAT
CGAGCATTGAAGGAGCCATC

Downstream 100 bases:

>100_bases
GCGGCTATGCCATCTTGCTCGCTGCCCACGGGAGCCGTGACCCTGCGAGCGCCGCGCAGTTTGGGGAGCTCGTGGCGCAG
GTCAAGGCGTTGGAACCGGG

Product: cobalt-precorrin-6Y C(5)-methyltransferase

Products: tetrahydrofolate; L-methionine

Alternate protein names: Precorrin-6y C515-Methyltransferase CbiE Subunit; Precorrin-6Y Methylase; Precorrin-6y C515-Methyltransferase Cbie Subunit; Precorrin-6y C5 15-Methyltransferase Subunit CbiE; Precorrin-6Y C5 15-Methyltransferase; Cobalamin Biosynthesis Protein/Precorrin-6Y Methylase; Precorrin-6b Methylase Methyltransferase Protein; Precorrin-6y Methylase Methyltransferase

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MIVCVGAGPGHLDFLTRRGAELVSNADVVAGFAAVVDVVRPLLLADQQVVTMGYRDQVAKLAEVAALHHAGKNCVVVFMG
DIHFSGFQFLERVETACGHPVETVPGISSAQLLASRGRVCFDETTFLTFHRRGDLTPFKTHLRDVLRAGRNAIVIPRPWD
FMPGDVAAYLLAHGASPAHRAEVWENLSRDEAAWRGTLGDLEGRAFSDMSILLIRALTPLPTGLEGEA

Sequences:

>Translated_228_residues
MIVCVGAGPGHLDFLTRRGAELVSNADVVAGFAAVVDVVRPLLLADQQVVTMGYRDQVAKLAEVAALHHAGKNCVVVFMG
DIHFSGFQFLERVETACGHPVETVPGISSAQLLASRGRVCFDETTFLTFHRRGDLTPFKTHLRDVLRAGRNAIVIPRPWD
FMPGDVAAYLLAHGASPAHRAEVWENLSRDEAAWRGTLGDLEGRAFSDMSILLIRALTPLPTGLEGEA
>Mature_228_residues
MIVCVGAGPGHLDFLTRRGAELVSNADVVAGFAAVVDVVRPLLLADQQVVTMGYRDQVAKLAEVAALHHAGKNCVVVFMG
DIHFSGFQFLERVETACGHPVETVPGISSAQLLASRGRVCFDETTFLTFHRRGDLTPFKTHLRDVLRAGRNAIVIPRPWD
FMPGDVAAYLLAHGASPAHRAEVWENLSRDEAAWRGTLGDLEGRAFSDMSILLIRALTPLPTGLEGEA

Specific function: Unknown

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.13

Molecular weight: Translated: 24680; Mature: 24680

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVCVGAGPGHLDFLTRRGAELVSNADVVAGFAAVVDVVRPLLLADQQVVTMGYRDQVAK
CEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHEECCHHHHHHH
LAEVAALHHAGKNCVVVFMGDIHFSGFQFLERVETACGHPVETVPGISSAQLLASRGRVC
HHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEE
FDETTFLTFHRRGDLTPFKTHLRDVLRAGRNAIVIPRPWDFMPGDVAAYLLAHGASPAHR
ECCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCCHHH
AEVWENLSRDEAAWRGTLGDLEGRAFSDMSILLIRALTPLPTGLEGEA
HHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIVCVGAGPGHLDFLTRRGAELVSNADVVAGFAAVVDVVRPLLLADQQVVTMGYRDQVAK
CEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHEECCHHHHHHH
LAEVAALHHAGKNCVVVFMGDIHFSGFQFLERVETACGHPVETVPGISSAQLLASRGRVC
HHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEE
FDETTFLTFHRRGDLTPFKTHLRDVLRAGRNAIVIPRPWDFMPGDVAAYLLAHGASPAHR
ECCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCCHHH
AEVWENLSRDEAAWRGTLGDLEGRAFSDMSILLIRALTPLPTGLEGEA
HHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-methyltetrahydrofolate; L-homocysteine

Specific reaction: 5-methyltetrahydrofolate + L-homocysteine = tetrahydrofolate + L-methionine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA