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The map label for this gene is ltrA [H]

Identifier: 94314824

GI number: 94314824

Start: 105084

End: 106037

Strand: Reverse

Name: ltrA [H]

Synonym: Rmet_5905

Alternate gene names: 94314824

Gene position: 106037-105084 (Counterclockwise)

Preceding gene: 94314825

Following gene: 94314823

Centisome position: 4.11

GC content: 63.94

Gene sequence:

>954_bases
ATGGATCTCAACGCCCTGCGCCTGTTCGTCGATATCGTCGACGCTGGCAATCTCAGCGCCGCCGCGCGCAAGCTCAAGAT
GACGCGCGCCAACGTCAGCTACCACCTCAAGGCTCTGGAGGAGGAACTCGGCGTGCAACTGCTGCGCCGGACGACCCGGC
ACGTGGAACCGACGCCGGTGGGCGCCGGACTGTACGAGCACGGCAAAAACATCCTGGGCGAAGTGGCTGCGGCCAACGCG
CTGATCAGCAGCATGGGCAAGAGCCTCCAGGGCCATGTGCGGCTGTCGGTACCCACCGGTCTGGGTCACACGATGATCTC
GCCGCTGCTGGTGCGCTTCAAGCAGCGCTATCCCGATATCACGCTCGACGTCGTCTTTGACAACCGCATCCACAACCTCG
TCTCCGAGGATGTGGAAGTGGCGTTGCGCATCATCTCCACGCCTCCCGACTCGGTCGTTGCCACCGAAATCGGCGGGGTG
GACTGGCTGCTTTGCGCCGCGCCGTCGTATCTGGCCGGACGCACGCCGCCCGCGCACCTTGCCGACCTGACGACCCATGC
GATCGTGTGCGCGTCGCCGATCGGGCAGAAACTCAAGGTGTCAGGCACGCGCGACGGCACCGCCGACCGCGAACAGGTGG
TACTGGAGCCAACCCTGAGCTCCGAGAACTTCGCGTTCCTCAAGGAGGCCGTGGTCGGCGGGCTCGGCATCGGCATTTTT
CCGCTCTATGCGGTGGACAAGGAACTGGCCAGCGGCGCGCTGGAATCGCTGCTCGGCGACTATCAGATCAGCGCGTTCGG
CAGCAAGCTGTACATGCTGACCATGCCCAATCGCTACCAGACCATGGCAACGCGCTACCTGCTTACGTTCCTGAGAACAG
AGCTGCAGGCGATCTGGCCGCGCATTCGTGCCGGCGGTGCCGACAGTGCCTATAGTGAGAACACTCAGGACTAA

Upstream 100 bases:

>100_bases
GCATCACGAGCACTGACCGGCCACCCGCCGCAGTCATGGCAAACTGAGGGGCCTTCGGGCCCCTTTTTATTTGCACGCGC
CCTTCGCTCTCCTCCCCGCC

Downstream 100 bases:

>100_bases
ACTGCGCGTGGCTCGCGTAGGAAGGAAGGCAATCATGGCAATGGCAGGCACTCTGGCTGGCCGGCTCAGCCGTATGAACA
GCCAGTTCGACATCATTCGT

Product: LysR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MDLNALRLFVDIVDAGNLSAAARKLKMTRANVSYHLKALEEELGVQLLRRTTRHVEPTPVGAGLYEHGKNILGEVAAANA
LISSMGKSLQGHVRLSVPTGLGHTMISPLLVRFKQRYPDITLDVVFDNRIHNLVSEDVEVALRIISTPPDSVVATEIGGV
DWLLCAAPSYLAGRTPPAHLADLTTHAIVCASPIGQKLKVSGTRDGTADREQVVLEPTLSSENFAFLKEAVVGGLGIGIF
PLYAVDKELASGALESLLGDYQISAFGSKLYMLTMPNRYQTMATRYLLTFLRTELQAIWPRIRAGGADSAYSENTQD

Sequences:

>Translated_317_residues
MDLNALRLFVDIVDAGNLSAAARKLKMTRANVSYHLKALEEELGVQLLRRTTRHVEPTPVGAGLYEHGKNILGEVAAANA
LISSMGKSLQGHVRLSVPTGLGHTMISPLLVRFKQRYPDITLDVVFDNRIHNLVSEDVEVALRIISTPPDSVVATEIGGV
DWLLCAAPSYLAGRTPPAHLADLTTHAIVCASPIGQKLKVSGTRDGTADREQVVLEPTLSSENFAFLKEAVVGGLGIGIF
PLYAVDKELASGALESLLGDYQISAFGSKLYMLTMPNRYQTMATRYLLTFLRTELQAIWPRIRAGGADSAYSENTQD
>Mature_317_residues
MDLNALRLFVDIVDAGNLSAAARKLKMTRANVSYHLKALEEELGVQLLRRTTRHVEPTPVGAGLYEHGKNILGEVAAANA
LISSMGKSLQGHVRLSVPTGLGHTMISPLLVRFKQRYPDITLDVVFDNRIHNLVSEDVEVALRIISTPPDSVVATEIGGV
DWLLCAAPSYLAGRTPPAHLADLTTHAIVCASPIGQKLKVSGTRDGTADREQVVLEPTLSSENFAFLKEAVVGGLGIGIF
PLYAVDKELASGALESLLGDYQISAFGSKLYMLTMPNRYQTMATRYLLTFLRTELQAIWPRIRAGGADSAYSENTQD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693193, Length=269, Percent_Identity=30.1115241635688, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786401, Length=258, Percent_Identity=31.3953488372093, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789440, Length=307, Percent_Identity=27.0358306188925, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=28.4280936454849, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789639, Length=260, Percent_Identity=25.7692307692308, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=24.3243243243243, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787589, Length=273, Percent_Identity=23.4432234432234, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788297, Length=123, Percent_Identity=35.7723577235772, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=136, Percent_Identity=25, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788706, Length=289, Percent_Identity=25.2595155709343, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082132, Length=273, Percent_Identity=24.1758241758242, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786713, Length=248, Percent_Identity=25, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789173, Length=262, Percent_Identity=24.0458015267176, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34352; Mature: 34352

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNALRLFVDIVDAGNLSAAARKLKMTRANVSYHLKALEEELGVQLLRRTTRHVEPTPV
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GAGLYEHGKNILGEVAAANALISSMGKSLQGHVRLSVPTGLGHTMISPLLVRFKQRYPDI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCE
TLDVVFDNRIHNLVSEDVEVALRIISTPPDSVVATEIGGVDWLLCAAPSYLAGRTPPAHL
EEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEHHHCCCHHHCCCCCCHHH
ADLTTHAIVCASPIGQKLKVSGTRDGTADREQVVLEPTLSSENFAFLKEAVVGGLGIGIF
HHHHHHHHEECCCCCCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHH
PLYAVDKELASGALESLLGDYQISAFGSKLYMLTMPNRYQTMATRYLLTFLRTELQAIWP
HHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
RIRAGGADSAYSENTQD
HHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLNALRLFVDIVDAGNLSAAARKLKMTRANVSYHLKALEEELGVQLLRRTTRHVEPTPV
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GAGLYEHGKNILGEVAAANALISSMGKSLQGHVRLSVPTGLGHTMISPLLVRFKQRYPDI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCE
TLDVVFDNRIHNLVSEDVEVALRIISTPPDSVVATEIGGVDWLLCAAPSYLAGRTPPAHL
EEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEHHHCCCHHHCCCCCCHHH
ADLTTHAIVCASPIGQKLKVSGTRDGTADREQVVLEPTLSSENFAFLKEAVVGGLGIGIF
HHHHHHHHEECCCCCCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHH
PLYAVDKELASGALESLLGDYQISAFGSKLYMLTMPNRYQTMATRYLLTFLRTELQAIWP
HHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
RIRAGGADSAYSENTQD
HHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]