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The map label for this gene is lldR [H]

Identifier: 94314451

GI number: 94314451

Start: 2279057

End: 2279860

Strand: Direct

Name: lldR [H]

Synonym: Rmet_5532

Alternate gene names: 94314451

Gene position: 2279057-2279860 (Clockwise)

Preceding gene: 94314450

Following gene: 94314455

Centisome position: 88.33

GC content: 57.34

Gene sequence:

>804_bases
ATGACCACCACTGTGAAAACTGCGGACACGCCTTTGGAAACGAATACGCCGCGCTTCGAGGCGGTACGCTCGGCACGTGC
GTTTGAAGAGATTGCAGATCAGATCCGAGCCGAGCTAGCCCAGGGGAGATTGAAGGTTGGCAGTCGACTCCCCGCTGAGC
GAGCCTTGGCCGTTCAGTTCGGCGTATCCCGGAACACGCTGCGAGAAGCGCTTAGATCCCTTGAGCACTCGGGACTTGTG
CGACTTCAAAAAGGTGCAAGCGGCGGTGCGTTTATCAGTGAAGGCTCCGGACTCGCTATCTCGAATAGCCTGATGGACCT
TTACCACGTAGGATCCATCACGCCCGACCAACTGACTCAGGCGCGGATCTGGCTGGAGTCAGTTATTGTCCGCGAGGCGT
GCGAGCGAGCGACTGCCGACGACCTGGCCGCCCTCGAGAGGAACATCGAAGAAGCGGCGCGTGCCTCGGAAGAAGGCGAC
TTTCCCCGTCGGGCAGAGCTTCACTTCGACTTTCACCGAACGCTTGCCAAGATGTCGGGCAATCCCATCATGGTCATCAT
GATGAATGGGCTGCTTGCCGTACTGGCTAACTTCGTAAATAGCATTGGAGAATACGAAAACAATTTCGTACTTCCGTCCC
GAAAGCGTTTCATGAAGCATATGCACGCGAAGGATGCCGAAGCGGCCGTAGCTGAAATGGAAGCCAGTCTCAAACGGCTT
CAACAAGCATATCTCTCGCGCGTAACGGAAAGCGACGCGGAACGGACGGTTCGACGCCGTGCCGCTCCCCGCAAGGGCAC
TTGA

Upstream 100 bases:

>100_bases
CGACTCATCTCCGTCACGTCAGCGACTACCTAGAAAGCGAAAGTAAGAAATCTGCGCGTAAGAAGAAGATTGCCGCATGA
CCCAGGCTGAGAAGGACACA

Downstream 100 bases:

>100_bases
TCAGGCATCAAGCCATTTGACTGCGGACGACAACTCGGCACGACTAGTCCGAAAGCCGTTTGCAGGATGGTGGGTGTCGG
GGTAGCCAAATGAGATCCCG

Product: putative GntR-family transcriptional regulator (HTH)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTTTVKTADTPLETNTPRFEAVRSARAFEEIADQIRAELAQGRLKVGSRLPAERALAVQFGVSRNTLREALRSLEHSGLV
RLQKGASGGAFISEGSGLAISNSLMDLYHVGSITPDQLTQARIWLESVIVREACERATADDLAALERNIEEAARASEEGD
FPRRAELHFDFHRTLAKMSGNPIMVIMMNGLLAVLANFVNSIGEYENNFVLPSRKRFMKHMHAKDAEAAVAEMEASLKRL
QQAYLSRVTESDAERTVRRRAAPRKGT

Sequences:

>Translated_267_residues
MTTTVKTADTPLETNTPRFEAVRSARAFEEIADQIRAELAQGRLKVGSRLPAERALAVQFGVSRNTLREALRSLEHSGLV
RLQKGASGGAFISEGSGLAISNSLMDLYHVGSITPDQLTQARIWLESVIVREACERATADDLAALERNIEEAARASEEGD
FPRRAELHFDFHRTLAKMSGNPIMVIMMNGLLAVLANFVNSIGEYENNFVLPSRKRFMKHMHAKDAEAAVAEMEASLKRL
QQAYLSRVTESDAERTVRRRAAPRKGT
>Mature_266_residues
TTTVKTADTPLETNTPRFEAVRSARAFEEIADQIRAELAQGRLKVGSRLPAERALAVQFGVSRNTLREALRSLEHSGLVR
LQKGASGGAFISEGSGLAISNSLMDLYHVGSITPDQLTQARIWLESVIVREACERATADDLAALERNIEEAARASEEGDF
PRRAELHFDFHRTLAKMSGNPIMVIMMNGLLAVLANFVNSIGEYENNFVLPSRKRFMKHMHAKDAEAAVAEMEASLKRLQ
QAYLSRVTESDAERTVRRRAAPRKGT

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=179, Percent_Identity=34.0782122905028, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789621, Length=156, Percent_Identity=34.6153846153846, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790780, Length=242, Percent_Identity=27.6859504132231, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786303, Length=201, Percent_Identity=26.865671641791, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789353, Length=208, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082208, Length=170, Percent_Identity=31.1764705882353, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29551; Mature: 29420

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTVKTADTPLETNTPRFEAVRSARAFEEIADQIRAELAQGRLKVGSRLPAERALAVQF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GVSRNTLREALRSLEHSGLVRLQKGASGGAFISEGSGLAISNSLMDLYHVGSITPDQLTQ
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHH
ARIWLESVIVREACERATADDLAALERNIEEAARASEEGDFPRRAELHFDFHRTLAKMSG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
NPIMVIMMNGLLAVLANFVNSIGEYENNFVLPSRKRFMKHMHAKDAEAAVAEMEASLKRL
CCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QQAYLSRVTESDAERTVRRRAAPRKGT
HHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTTVKTADTPLETNTPRFEAVRSARAFEEIADQIRAELAQGRLKVGSRLPAERALAVQF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GVSRNTLREALRSLEHSGLVRLQKGASGGAFISEGSGLAISNSLMDLYHVGSITPDQLTQ
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHH
ARIWLESVIVREACERATADDLAALERNIEEAARASEEGDFPRRAELHFDFHRTLAKMSG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
NPIMVIMMNGLLAVLANFVNSIGEYENNFVLPSRKRFMKHMHAKDAEAAVAEMEASLKRL
CCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QQAYLSRVTESDAERTVRRRAAPRKGT
HHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]